Zhi-yuan Zhu

发表

Blockage of progesterone receptor effectively protects pancreatic islet beta cell viability

Xu Shen, Jing Chen, Li-li Chen, 2013, Steroids.

Statistical molecular identification of kinase inhibitors to disrupt c‐Jun N‐terminal protein kinase involved in paraquat‐mediated toxicological effects

Yu-Ping Yang, Zhi-yuan Zhu, Yu‐Mei Jin, 2017 .

Arctigenin enhances swimming endurance of sedentary rats partially by regulation of antioxidant pathways

Xu Shen, Li-Hong Hu, Ruo-ming Wu, 2014, Acta Pharmacologica Sinica.

Structural Basis for Small Molecule NDB (N-Benzyl-N-(3-(tert-butyl)-4-hydroxyphenyl)-2,6-dichloro-4-(dimethylamino) Benzamide) as a Selective Antagonist of Farnesoid X Receptor α (FXRα) in Stabilizing the Homodimerization of the Receptor*

Peng Liu, Xin Xu, Xing Xu, 2015, The Journal of Biological Chemistry.

ETA as a novel Kv2.1 inhibitor ameliorates β‐cell dysfunction and hyperglycaemia

Jing Chen, L. Quan, Zhi-yuan Zhu, 2018, Clinical and experimental pharmacology & physiology.

Structure-based analysis and rational design of human peroxiredoxin-1's C-terminus-derived peptides to target sulfiredoxin-1 in pancreatic cancer.

Zhou Zhang, Zhi-yuan Zhu, Rong-yuan Qiu, 2022, Biophysical chemistry.

Small molecule TBTC as a new selective retinoid X receptor α agonist improves behavioral deficit in Alzheimer's disease model mice.

W. Duan, Yanyan Sun, Xu Shen, 2015, European journal of pharmacology.

Design, synthesis and SAR study of hydroxychalcone inhibitors of human β-secretase (BACE1)

Chenjing Li, Xu Shen, Lihong Hu, 2011, Journal of enzyme inhibition and medicinal chemistry.

Aβ regulation-based multitarget strategy for drug discovery against Alzheimer’s disease

Chenjing Li, Wei Jiang, Xu Shen, 2015, Reviews in the neurosciences.

Arctigenin Effectively Ameliorates Memory Impairment in Alzheimer's Disease Model Mice Targeting Both β-Amyloid Production and Clearance

Hualiang Jiang, Chenjing Li, Xu Shen, 2013, The Journal of Neuroscience.

L655,240, acting as a competitive BACE1 inhibitor, efficiently decreases β-amyloid peptide production in HEK293-APPswe cells

Xu Shen, Ye-chun Xu, Li-li Chen, 2012, Acta Pharmacologica Sinica.

Thamnolia vermicularis extract improves learning ability in APP/PS1 transgenic mice by ameliorating both Aβ and Tau pathologies

Xu Shen, Li-Hong Hu, V. Rukachaisirikul, 2016, Acta Pharmacologica Sinica.

Nitazoxanide, an anti-parasitic drug, efficiently ameliorates learning and memory impairments in AD model mice

Xu Shen, J. Chen, Jin Ren, 2019, Acta Pharmacologica Sinica.

Glaucocalyxin A as a natural product increases amyloid &bgr; clearance and decreases tau phosphorylation involving the mammalian target of rapamycin signaling pathway

Zhimin Wang, Zhi-yuan Zhu, Zhiwei Wang, 2019, Neuroreport.

LX2343 alleviates cognitive impairments in AD model rats by inhibiting oxidative stress-induced neuronal apoptosis and tauopathy

Xu Shen, Li-Hong Hu, V. Rukachaisirikul, 2017, Acta Pharmacologica Sinica.

NDB stabilizes hFXR homodimerization

Xu Shen, P. Liu, Jing Chen, 2015 .

Structural basis for small molecule NDB as a selective antagonist of Farnesoid X receptor ( FXR ) in stabilizing the homodimerization of the receptor

Xu Shen, Lihong Hu, Li-li Chen, 2015 .

Latanoprost effectively ameliorates glucose and lipid disorders in db/db and ob/ob mice

Xu Shen, Li-li Chen, Gaihong Wang, 2013, Diabetologia.

2,2′,4′‐Trihydroxychalcone from Glycyrrhiza glabra as a new specific BACE1 inhibitor efficiently ameliorates memory impairment in mice

Hualiang Jiang, Chenjing Li, Xu Shen, 2010, Journal of neurochemistry.

Synthesis and decreasing Aβ content evaluation of arctigenin-4-yl carbamate derivatives.

Xu Shen, Lihong Hu, Min Lei, 2016, Bioorganic & medicinal chemistry letters.