Hongyu Yang

发表

The Development of Pharmacophore Modeling: Generation and Recent Applications in Drug Discovery.

Xin Lu, Hongyu Yang, Wei Qu, 2018, Current pharmaceutical design.

Expansion of the scaffold diversity for the development of highly selective butyrylcholinesterase (BChE) inhibitors: Discovery of new hits through the pharmacophore model generation, virtual screening and molecular dynamics simulation.

Q. Guo, Wenyuan Liu, F. Feng, 2019, Bioorganic chemistry.

Small molecular Nrf2 inhibitors as chemosensitizers for cancer therapy.

Wenyuan Liu, F. Feng, Y. Qiao, 2020, Future medicinal chemistry.

Design, synthesis and 3D-QSAR study of cytotoxic flavonoid derivatives

Y. Lou, Yongping Yu, Jian-zhong Chen, 2011, Molecular Diversity.

N-Benzyl Benzamide Derivatives as Selective Sub-Nanomolar Butyrylcholinesterase Inhibitors for Possible Treatment in Advanced Alzheimer's Disease.

W. Li, Wenyuan Liu, F. Feng, 2022, Journal of medicinal chemistry.

Cysteinyl leukotrienes synthesis is involved in aristolochic acid I-induced apoptosis in renal proximal tubular epithelial cells.

Y. Lou, Jia-jun Cheng, Yun Tan, 2011, Toxicology.

Dual GSK-3β/AChE Inhibitors as a New Strategy for Multitargeting Anti-Alzheimer's Disease Drug Discovery.

F. Feng, Haopeng Sun, Wei Qu, 2018, ACS medicinal chemistry letters.

Design, synthesis and evaluation of fused hybrids with acetylcholinesterase inhibiting and Nrf2 activating functions for Alzheimer's disease.

Wenyuan Liu, F. Feng, Y. Qiao, 2022, European journal of medicinal chemistry.

Discovery and biological evaluation of a novel highly potent selective butyrylcholinsterase inhibitor.

Wenyuan Liu, F. Feng, Shuaishuai Xing, 2020, Journal of medicinal chemistry.

1 Synthesis and Structure-Activity Relationships of 2 Resorcinol Derivatives as Highly Potent Tyrosinase 3 Inhibitors 4

Q. Xia, Yao Chen, Hongyu Yang, 2018 .

Anti-tumor effects of B-2, a novel 2,3-disubstituted 8-arylamino-3H-imidazo[4,5-g]quinazoline derivative, on the human lung adenocarcinoma A549 cell line in vitro and in vivo.

Y. Lou, Xin Huang, Lingyan Gao, 2011, Chemico-biological interactions.

Discovery of a Selective 6-Hydroxy-1, 4-Diazepan-2-one Containing Butyrylcholinesterase Inhibitor by Virtual Screening and MM-GBSA Rescoring

Xin Lu, Haopeng Sun, K. H. Hong, 2020, Dose-response : a publication of International Hormesis Society.

Discovery of Selective Butyrylcholinesterase (BChE) Inhibitors through a Combination of Computational Studies and Biological Evaluations

Q. Xia, Xin Lu, Li Xu, 2019, Molecules.

Recent progress in the identification of selective butyrylcholinesterase inhibitors for Alzheimer's disease.

Haopeng Sun, Yao Chen, Hongyu Yang, 2017, European journal of medicinal chemistry.

Synthesis and activity of miconazole derivatives as dual BChE/IDO1 inhibitors for the treatment of Alzheimer's disease.

Wenyuan Liu, F. Feng, Yijun Liu, 2021, Future medicinal chemistry.

Investigation of multi-target-directed ligands (MTDLs) with butyrylcholinesterase (BuChE) and indoleamine 2,3-dioxygenase 1 (IDO1) inhibition: The design, synthesis of miconazole analogues targeting Alzheimer's disease.

F. Feng, Yaoyao Bian, Xin Lu, 2018, Bioorganic & medicinal chemistry.

Identification by shape-based virtual screening and evaluation of new tyrosinase inhibitors

Haopeng Sun, Yuan Sun, Chen Kang, 2018, PeerJ.

Design and evaluation of Nrf2 activators with 1,3,4-oxa/thiadiazole core as neuro-protective agents against oxidative stress in PC-12 cells.

Wenyuan Liu, F. Feng, Y. Qiao, 2019, Bioorganic & medicinal chemistry letters.

Small molecule modulators targeting protein kinase CK1 and CK2.

Q. Guo, Wenyuan Liu, F. Feng, 2019, European journal of medicinal chemistry.

Discovery of new acetylcholinesterase and butyrylcholinesterase inhibitors through structure-based virtual screening

Yuqiong Pei, R. Tan, Wei Li, 2017 .

Design, synthesis, biological evaluation, and molecular modeling studies of quinoline-ferulic acid hybrids as cholinesterase inhibitors.

Q. Guo, Wenyuan Liu, F. Feng, 2019, Bioorganic chemistry.

Discovery, molecular dynamic simulation and biological evaluation of structurally diverse cholinesterase inhibitors with new scaffold through shape-based pharmacophore virtual screening.

Wenyuan Liu, F. Feng, Xin Lu, 2019, Bioorganic chemistry.

Design, Synthesis, and Evaluation of Acetylcholinesterase and Butyrylcholinesterase Dual-Target Inhibitors against Alzheimer’s Diseases

Zhongwei Huang, Yan Guo, Zongliang Liu, 2020, Molecules.

Small molecule PROTACs in targeted therapy: An emerging strategy to induce protein degradation.

Bin Chen, Haopeng Sun, Kui Du, 2019, European journal of medicinal chemistry.

Synthesis and bioevaluation of new tacrine-cinnamic acid hybrids as cholinesterase inhibitors against Alzheimer’s disease

Yuqiong Pei, R. Tan, Yaoyao Bian, 2017, Journal of enzyme inhibition and medicinal chemistry.

Synthesis, pharmacology and molecular docking on multifunctional tacrine-ferulic acid hybrids as cholinesterase inhibitors against Alzheimer’s disease

Yuqiong Pei, Yaoyao Bian, Haopeng Sun, 2018, Journal of enzyme inhibition and medicinal chemistry.

XJW20, a novel oxoindole derivative, induces G2/M arrest and apoptosis selectively in K562 leukemia cell line.

Y. Lou, Wenteng Chen, Yongping Yu, 2010, Chemico-biological interactions.

Design, synthesis, in vitro and in vivo evaluation of benzylpiperidine-linked 1,3-dimethylbenzimidazolinones as cholinesterase inhibitors against Alzheimer’s disease

Wenyuan Liu, F. Feng, Yan Guo, 2019, Journal of enzyme inhibition and medicinal chemistry.

Dual GSK-3β/AChE Inhibitors as a New Strategy for Multitargeting Anti-Alzheimer's Disease Drug Discovery.

F. Feng, Haopeng Sun, Wei Qu, 2018, ACS medicinal chemistry letters.