Yunjie Zhao

发表

Kaempferol attenuates hyperglycemia-induced cardiac injuries by inhibiting inflammatory responses and oxidative stress

G. Liang, Jianchang Qian, Xuemei Chen, 2018, Endocrine.

11β-HSD1 inhibition ameliorates diabetes-induced cardiomyocyte hypertrophy and cardiac fibrosis through modulation of EGFR activity

G. Liang, Yi Wang, Weixin Li, 2017, Oncotarget.

New EGFR inhibitor, 453, prevents renal fibrosis in angiotensin II-stimulated mice.

Xiaokun Li, G. Liang, Peng Zhong, 2016, European journal of pharmacology.

Inhibition of high glucose-induced inflammation and fibrosis by a novel curcumin derivative prevents renal and heart injury in diabetic mice.

G. Liang, Xi Yang, Suqing Zheng, 2017, Toxicology letters.

EGFR inhibition attenuates diabetic nephropathy through decreasing ROS and endoplasmic reticulum stress

G. Liang, Peng Zhong, C. Zou, 2017, Oncotarget.

Curcumin protects hearts from FFA-induced injury by activating Nrf2 and inactivating NF-κB both in vitro and in vivo.

S. Chakrabarti, G. Liang, Peng Zhong, 2015, Journal of molecular and cellular cardiology.

Design, synthesis, and structure–activity relationships of 2-benzylidene-1-indanone derivatives as anti-inflammatory agents for treatment of acute lung injury

G. Liang, Lingfeng Chen, Zhiguo Liu, 2018, Drug design, development and therapy.

11β-Hydroxysteroid Dehydrogenase Type 1(11β-HSD1) mediates insulin resistance through JNK activation in adipocytes

G. Liang, Z. Khan, Haimin Yin, 2016, Scientific Reports.

Macrophage-specific MyD88 deletion and pharmacological inhibition prevents liver damage in non-alcoholic fatty liver disease via reducing inflammatory response.

Yi Wang, Weiwei Zhu, Wu Luo, 2022, Biochimica et biophysica acta. Molecular basis of disease.

CDK9 inhibition improves diabetic nephropathy by reducing inflammation in the kidneys.

Xiang Hu, G. Liang, X. Guan, 2021, Toxicology and applied pharmacology.

Development of resveratrol-curcumin hybrids as potential therapeutic agents for inflammatory lung diseases.

Fengli Xu, G. Liang, Weitao Fu, 2017, European journal of medicinal chemistry.

Synthesis and anti-inflammatory evaluation of novel mono-carbonyl analogues of curcumin in LPS-stimulated RAW 264.7 macrophages.

Chengguang Zhao, Xiaokun Li, G. Liang, 2010, European journal of medicinal chemistry.

Inhibition of JNK by novel curcumin analog C66 prevents diabetic cardiomyopathy with a preservation of cardiac metallothionein expression.

Wanqing Sun, L. Cai, G. Liang, 2014, American journal of physiology. Endocrinology and metabolism.

A novel monocarbonyl analogue of curcumin, (1E,4E)-1,5-bis(2,3-dimethoxyphenyl)penta-1,4-dien-3-one, induced cancer cell H460 apoptosis via activation of endoplasmic reticulum stress signaling pathway.

Jian Xiao, Xiaokun Li, G. Liang, 2011, Journal of medicinal chemistry.

Discovery of new MD2-targeted anti-inflammatory compounds for the treatment of sepsis and acute lung injury.

Xiaokun Li, Gaozhi Chen, Lili Fu, 2017, European journal of medicinal chemistry.

New MD2 inhibitors derived from curcumin with improved anti-inflammatory activity.

H. Lum, Zhongxiang Xiao, G. Liang, 2018, European journal of medicinal chemistry.

Discovery of a New Inhibitor of Myeloid Differentiation 2 from Cinnamamide Derivatives with Anti-Inflammatory Activity in Sepsis and Acute Lung Injury.

Xiaokun Li, Gaozhi Chen, Lili Fu, 2016, Journal of medicinal chemistry.

Inhibition Of JNK Phosphorylation By Curcumin Analog C66 Protects LPS-Induced Acute Lung Injury

Bing Zhang, Zhongxiang Xiao, Fengli Xu, 2019, Drug design, development and therapy.

Design and synthesis novel di-carbonyl analogs of curcumin (DACs) act as potent anti-inflammatory agents against LPS-induced acute lung injury (ALI).

G. Liang, Jianchang Qian, Zhiguo Liu, 2019, European journal of medicinal chemistry.

DDDT_A_215712 4161..4171

Bing Zhang, Zhongxiang Xiao, Fengli Xu, 2019 .

Synthesis and Anti-inflammatory Evaluation of Novel Benzimidazole and Imidazopyridine Derivatives.

Gaozhi Chen, G. Liang, Shulin Yang, 2013, ACS medicinal chemistry letters.

Design, Synthesis, and Structure–Activity Relationship Analysis of Thiazolo[3,2‐a]pyrimidine Derivatives with Anti‐inflammatory Activity in Acute Lung Injury

G. Liang, Weitao Fu, Lingfeng Chen, 2017, ChemMedChem.

Palladium-catalyzed ortho C–H bond alkylation of benzylamides with α-bromo ketones

Chenglong Li, Guang Liang, Yunjie Zhao, 2016 .

One-step construction of unsymmetrical thioureas and oxazolidinethiones from amines and carbon disulfide via a cascade reaction sequence

Guang Liang, Q. Dai, Yunjie Zhao, 2019, RSC advances.

Synthesis, biological evaluation, and molecular docking study of novel allyl-retrochalcones as a new class of protein tyrosine phosphatase 1B inhibitors.

Ying Su, Suqing Zheng, Weiwei Zhu, 2019, Bioorganic & medicinal chemistry.

Synthesis and crystal structure of chalcones as well as on cytotoxicity and antibacterial properties

Yuepiao Cai, Shulin Yang, Xiao-ping Wu, 2011, Medicinal Chemistry Research.

Novel curcumin analog C66 prevents diabetic nephropathy via JNK pathway with the involvement of p300/CBP-mediated histone acetylation.

L. Cai, G. Liang, Y. Xin, 2015, Biochimica et biophysica acta.

Synthesis and Anti-inflammatory Evaluation of ( R)-, ( S)-, and (±)-Sanjuanolide Isolated from Dalea frutescens.

Zhongxiang Xiao, G. Liang, Zhiguo Liu, 2019, Journal of Natural Products.

cyy-287, a novel pyrimidine-2,4-diamine derivative, inhibits tumor growth of EGFR-driven non-small cell lung cancer via the ERK pathway

Jianchang Qian, Zhiguo Liu, Yunjie Zhao, 2022, Acta biochimica et biophysica Sinica.

Small molecule inhibition of fibroblast growth factor receptors in cancer.

Xiaokun Li, Gaozhi Chen, G. Liang, 2013, Cytokine & growth factor reviews.

Potent inhibition of gastric cancer cells by a natural compound via inhibiting TrxR1 activity and activating ROS-mediated p38 MAPK pathway

Wei He, P. Zou, Yiqun Xia, 2019, Free radical research.

Discovery of Potent and Orally Bioavailable Platelet-Derived Growth Factor Receptor (PDGFR) Inhibitors for the Treatment of Osteosarcoma.

P. Liu, Xiaokun Li, Jianchang Qian, 2022, Journal of medicinal chemistry.

The therapeutic potential of a novel non-ATP-competitive fibroblast growth factor receptor 1 inhibitor on gastric cancer

Xiaokun Li, G. Liang, Yiqun Xia, 2015, Anti-cancer drugs.

Discovery and identification of new non-ATP competitive FGFR1 inhibitors with therapeutic potential on non-small-cell lung cancer.

Chengguang Zhao, Xiaokun Li, J. Ji, 2014, Cancer letters.

Inhibition of JNK Phosphorylation by a Novel Curcumin Analog Prevents High Glucose–Induced Inflammation and Apoptosis in Cardiomyocytes and the Development of Diabetic Cardiomyopathy

Xiaokun Li, L. Cai, G. Liang, 2014, Diabetes.

Targeting JNK by a New Curcumin Analog to Inhibit NF-kB-Mediated Expression of Cell Adhesion Molecules Attenuates Renal Macrophage Infiltration and Injury in Diabetic Mice

Xiaokun Li, L. Cai, G. Liang, 2013, PloS one.

Evaluation and discovery of novel synthetic chalcone derivatives as anti-inflammatory agents.

F. Ye, Xiaokun Li, G. Liang, 2011, Journal of medicinal chemistry.

cyy260 suppresses the proliferation, migration and tumor growth of osteosarcoma by targeting PDGFR-β signaling pathway.

Xiaokun Li, Jianxia Zhang, Zhiguo Liu, 2022, Chemico-biological interactions.

Synthesis and biological evaluation of novel semi-conservative mono-carbonyl analogs of curcumin as anti-inflammatory agents

P. Zou, Zhe Wang, Yuepiao Cai, 2015 .

Synthesis and crystal structure of chalcones as well as on cytotoxicity and antibacterial properties

Xiaokun Li, G. Liang, Yuepiao Cai, 2012, Medicinal Chemistry Research.

Inhibition of MAPK-mediated ACE expression by compound C66 prevents STZ-induced diabetic nephropathy

Zhe Wang, L. Cai, G. Liang, 2013, Journal of cellular and molecular medicine.

Macrophage DCLK1 promotes obesity-induced cardiomyopathy via activating RIP2/TAK1 signaling pathway

Yi Wang, Weiwei Zhu, Bin Yang, 2023, Cell death & disease.

Targeting extracellular matrix through phytochemicals: a promising approach of multi-step actions on the treatment and prevention of cancer

D. Liang, Zhenyi Luo, Yunjie Zhao, 2023, Frontiers in pharmacology.

Curcumin protects hearts from FFA-induced injury by activating Nrf2 and inactivating NF-κB both in vitro and in vivo.

S. Chakrabarti, G. Liang, Peng Zhong, 2015, Journal of molecular and cellular cardiology.

Inhibition of JNK by novel curcumin analog C66 prevents diabetic cardiomyopathy with a preservation of cardiac metallothionein expression.

Wanqing Sun, L. Cai, G. Liang, 2014, American journal of physiology. Endocrinology and metabolism.

Dissolution changes in drug-amino acid/biotin co-amorphous systems: decreased/increased dissolution during storage without recrystallization.

Wenqi Wu, G. Liang, Lina Yin, 2023, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Synthesis and biological evaluation of novel semi-conservative monocarbonyl analogs of curcumin as anti-inflammatory agents

P. Zou, G. Liang, Zhe Wang, 2015 .

Scholarship@Western Scholarship@Western

Haimin Yin, Kesong Peng, Yong Pan, 2022 .