Doris Riether

发表

Epigenetic Modification 6‐Methyladenosine Can Impact the Potency and Specificity of siRNA

E. Simon, Anna M. Rydzik, J. Rippmann, 2020, Chembiochem : a European journal of chemical biology.

Selective CB2 receptor agonists. Part 1: the identification of novel ligands through computer-aided drug design (CADD) approaches.

P. Cirillo, E. Hickey, M. Gemkow, 2015, Bioorganic & medicinal chemistry letters.

5-Aminomethylbenzimidazoles as potent ITK antagonists.

J. Woska, D. Jeanfavre, M. Kashem, 2009, Bioorganic & medicinal chemistry letters.

Optimization of drug-like properties of nonsteroidal glucocorticoid mimetics and identification of a clinical candidate.

U. Patel, Yancey D. Ward, Alison J Kukulka, 2014, ACS medicinal chemistry letters.

Identification of highly efficacious glucocorticoid receptor agonists with a potential for reduced clinical bone side effects.

M. Emmanuel, Alison J Kukulka, G. Nabozny, 2014, Journal of medicinal chemistry.

Nonsteroidal dissociated glucocorticoid agonists containing azaindoles as steroid A-ring mimetics.

T. Gilmore, C. Torcellini, Alison J Kukulka, 2010, Journal of medicinal chemistry.

Selective CB2 receptor agonists. Part 3: the optimization of a piperidine-based series that demonstrated efficacy in an in vivo neuropathic pain model.

P. Cirillo, E. Hickey, A. Bartolozzi, 2015, Bioorganic & medicinal chemistry letters.

Selective cannabinoid receptor 2 modulators: a patent review 2009 – present

Doris Riether, 2012, Expert opinion on therapeutic patents.

Selective CB2 receptor agonists. Part 2: Structure-activity relationship studies and optimization of proline-based compounds.

E. Hickey, M. Gemkow, A. Ceci, 2015, Bioorganic & medicinal chemistry letters.

Aryl 1,4-diazepane compounds as potent and selective CB2 agonists: optimization of drug-like properties and target independent parameters.

Sabine Löbbe, M. Gemkow, Mita Patel, 2011, Bioorganic & medicinal chemistry letters.

1,4-Diazepane compounds as potent and selective CB2 agonists: optimization of metabolic stability.

Daniel R. Albaugh, P. Cirillo, Sabine Löbbe, 2011, Bioorganic & medicinal chemistry letters.

Morpholine containing CB2 selective agonists.

Sabine Löbbe, A. Ebneth, M. Gemkow, 2009, Bioorganic & medicinal chemistry letters.

Arylsulfonamide CB2 receptor agonists: SAR and optimization of CB2 selectivity.

B. Dymock, Sabine Löbbe, M. Brewer, 2008, Bioorganic & medicinal chemistry letters.

Discovery and optimization of oxadiazole-based FLAP inhibitors.

Asitha Abeywardane, J. M. Hutzler, A. Bartolozzi, 2017, Bioorganic & medicinal chemistry letters.

Synthesis of 2'-modified N6-methyladenosine phosphoramidites and their incorporation into siRNA.

Anna M. Rydzik, D. Gottschling, Doris Riether, 2023, Bioorganic & medicinal chemistry letters.

Synthesis of the C-ring fragment of cobyric acid

J. Mulzer, Doris Riether, 1999 .

Access to 1'-Amino Carbocyclic Phosphoramidite to Enable Postsynthetic Functionalization of Oligonucleotides.

Anna M. Rydzik, D. Gottschling, Doris Riether, 2021, Organic letters.

Discovery of a Novel Potent and Selective HSD17B13 Inhibitor, BI-3231, a Well-Characterized Chemical Probe Available for Open Science

T. Fox, C. Tautermann, C. Hoenke, 2023, Journal of medicinal chemistry.

Synthesis, SAR, and series evolution of novel oxadiazole-containing 5-lipoxygenase activating protein inhibitors: discovery of 2-[4-(3-{(r)-1-[4-(2-amino-pyrimidin-5-yl)-phenyl]-1-cyclopropyl-ethyl}-[1,2,4]oxadiazol-5-yl)-pyrazol-1-yl]-N,N-dimethyl-acetamide (BI 665915).

M. Hao, Asitha Abeywardane, T. Morwick, 2015, Journal of medicinal chemistry.

Reactivity of functional groups on the protein surface: development of epoxide probes for protein labeling.

Doris Riether, D. Sames, Dalibor Sames, 2003, Journal of the American Chemical Society.

Electrochemical Synthesis and Structure Analysis of Neocoenzyme B12 – An Epimer of Coenzyme B12 with a Remarkably Flexible Organometallic Group

B. Kräutler, M. Tollinger, G. Kontaxis, 1999 .

Discovery of a potent and dissociated non-steroidal glucocorticoid receptor agonist containing an alkyl carbinol pharmacophore.

J. Proudfoot, C. Torcellini, Alison J Kukulka, 2014, Bioorganic & medicinal chemistry letters.

Identification of Highly Selective Orexin 1 Receptor Antagonists Driven by Structure-Based Design

Roland Pfau, Uta Lessel, Marco Ferrara, 2021, J. Chem. Inf. Model..

Total Synthesis of Cobyric Acid: Historical Development and Recent Synthetic Innovations

J. Mulzer, Doris Riether, 2003 .