Thulasi Warrier

发表

Differentially Detectable Mycobacterium tuberculosis Cells in Sputum from Treatment-Naive Subjects in Haiti and Their Proportionate Increase after Initiation of Treatment

C. Nathan, J. Pape, L. Mathurin, 2018, mBio.

Benzimidazole-based compounds kill Mycobacterium tuberculosis.

C. Nathan, Xiuju Jiang, Gang Liu, 2014, European journal of medicinal chemistry.

Nonsteroidal anti-inflammatory drug sensitizes Mycobacterium tuberculosis to endogenous and exogenous antimicrobials

C. Nathan, O. Ouerfelli, H. Deng, 2012, Proceedings of the National Academy of Sciences.

Integrated genomics and chemical biology herald an era of sophisticated antibacterial discovery, from defining essential genes to target elucidation.

A. Clatworthy, D. Hung, Thulasi Warrier, 2022, Cell chemical biology.

Antigen 85C Inhibition Restricts Mycobacterium tuberculosis Growth through Disruption of Cord Factor Biosynthesis

S. Kaufmann, B. Schlegel, A. Diehl, 2012, Antimicrobial Agents and Chemotherapy.

New Evidence for the Complexity of the Population Structure of Mycobacterium tuberculosis Increases the Diagnostic and Biologic Challenges.

C. Nathan, V. Dartois, Kohta Saito, 2016, American journal of respiratory and critical care medicine.

A Multistress Model for High Throughput Screening Against Nonreplicating Mycobacterium tuberculosis.

C. Nathan, Thulasi Warrier, B. Gold, 2021, Methods in molecular biology.

A multi-stress model for high throughput screening against non-replicating Mycobacterium tuberculosis.

C. Nathan, Thulasi Warrier, B. Gold, 2015, Methods in molecular biology.

Novel Cephalosporins Selectively Active on Nonreplicating Mycobacterium tuberculosis

C. Nathan, M. Zimmerman, J. Aubé, 2016, Journal of medicinal chemistry.

Synthetic calanolides with bactericidal activity against replicating and nonreplicating Mycobacterium tuberculosis.

C. Nathan, Gang Liu, S. J. Brickner, 2014, Journal of medicinal chemistry.

Novel small molecules targeting Ag85C, mycolyl transferase of Mycobacterium tuberculosis

Thulasi Warrier, 2010 .

X-ray Structure of 4,4′-Dihydroxybenzophenone Mimicking Sterol Substrate in the Active Site of Sterol 14α-Demethylase (CYP51)*♦

S. Kaufmann, J. V. von Kries, L. Podust, 2008, Journal of Biological Chemistry.

Rifamycin congeners kanglemycins are active against rifampicin-resistant bacteria via a distinct mechanism

Paula Y. Calle, M. Glickman, S. Brady, 2018, Nature Communications.

Mutations in pmrB Confer Cross-Resistance between the LptD Inhibitor POL7080 and Colistin in Pseudomonas aeruginosa

Bradley E. Poulsen, D. Hung, B. Pentelute, 2019, Antimicrobial Agents and Chemotherapy.

Mutations in pmrB confer cross-resistance to the LptD inhibitor POL7080 and colistin in Pseudomonas aeruginosa

Bradley E. Poulsen, D. Hung, B. Pentelute, 2019, bioRxiv.

Rifamycin action on RNA polymerase in antibiotic-tolerant Mycobacterium tuberculosis results in differentially detectable populations

W. Jacobs, C. Nathan, Lina Kaminski, 2017, Proceedings of the National Academy of Sciences.

Oxidative damage and delayed replication allow viable Mycobacterium tuberculosis to go undetected

C. Nathan, Xiuju Jiang, Kohta Saito, 2021, Science Translational Medicine.

Identification of a Mycothiol-Dependent Nitroreductase from Mycobacterium tuberculosis

J. Sacchettini, T. Ioerger, J. Vendôme, 2018, ACS infectious diseases.

Small-Molecule Scaffolds for CYP51 Inhibitors Identified by High-Throughput Screening and Defined by X-Ray Crystallography

M. Waterman, S. Kaufmann, H. Oschkinat, 2007, Antimicrobial Agents and Chemotherapy.

N-methylation of a bactericidal compound as a resistance mechanism in Mycobacterium tuberculosis

T. Ioerger, C. Nathan, M. Luo, 2016, Proceedings of the National Academy of Sciences.

Rifamycin congeners kanglemycins are active against rifampicin-resistant bacteria via a distinct mechanism

Paula Y. Calle, M. Glickman, S. Brady, 2018, Nature Communications.

Rapid, Semiquantitative Assay To Discriminate among Compounds with Activity against Replicating or Nonreplicating Mycobacterium tuberculosis

C. Nathan, J. Warren, Thulasi Warrier, 2015, Antimicrobial Agents and Chemotherapy.

Identification of Novel Anti-mycobacterial Compounds by Screening a Pharmaceutical Small-Molecule Library against Nonreplicating Mycobacterium tuberculosis.

Gonzalo Colmenarejo, A. Álvarez-Pedraglio, C. Nathan, 2015, ACS infectious diseases.

Identification of Small‐Molecule Scaffolds for P450 Inhibitors

J. V. Kries, L. Podust, Thulasi Warrier, 2010, Current protocols in microbiology.

N,C-Capped dipeptides with selectivity for mycobacterial proteasome over human proteasomes: role of S3 and S1 binding pockets.

M. Sintchak, L. Dick, C. Nathan, 2013, Journal of the American Chemical Society.

Visualization of the Charcoal Agar Resazurin Assay for Semi-quantitative, Medium-throughput Enumeration of Mycobacteria

C. Nathan, Thulasi Warrier, Julia Roberts, 2016, Journal of visualized experiments : JoVE.

Nonsteroidal anti-inflammatory drug sensitizes Mycobacterium tuberculosis to endogenous and exogenous antimicrobials

C. Nathan, O. Ouerfelli, Ronald B. Realubit, 2012 .

Old fold in a new X‐ray diffraction dataset? Low‐resolution molecular replacement using representative structural templates can provide phase information

B. Gopal, M. Rajavel, Thulasi Warrier, 2006, Proteins.

Nonsteroidal anti-inflammatory drug sensitizes Mycobacterium tuberculosis to endogenous and exogenous antimicrobials

C. Nathan, O. Ouerfelli, Ronald B. Realubit, 2012, Proceedings of the National Academy of Sciences.