Farooqi Is

Human gain-of-function MC4R variants show signaling bias and protect against obesity

Lotta La, M. J, Mendes de Oliveira E, 2020, Yearbook of Paediatric Endocrinology.

Genetic aspects of severe childhood obesity.

Farooqi Is, 2006 .

Human MC4R variants affect endocytosis, trafficking and dimerization revealing multiple cellular mechanisms involved in weight regulation

M. Babu, I. Farooqi, M. Bouvier, 2021, Cell reports.

Genetic architecture of human thinness compared to severe obesity

E. Zeggini, S. O’Rahilly, I. Barroso, 2019, PLoS genetics.

Rare Antagonistic Leptin Variants and Severe, Early-Onset Obesity.

S. Savvides, P. Fischer-Posovszky, I. Farooqi, 2023, The New England journal of medicine.

MC4R agonism promotes durable weight loss in patients with leptin receptor deficiency

M. J, Farooqi Is, Krude H, 2018, Nature Medicine.

Oral glutamine increases circulating glucagon-like peptide 1, glucagon, and insulin concentrations in lean, obese, and type 2 diabetic subjects.

J. Holst, A. M. Habib, F. Reimann, 2009, The American journal of clinical nutrition.

Obesity-Associated GNAS Mutations and the Melanocortin Pathway.

I. Barroso, I. Farooqi, P. Clayton, 2021, The New England journal of medicine.