R. Wolin

发表

Optimization of triaryl bis-sulfones as cannabinoid-2 receptor ligands.

Jie Wu, C. Lunn, S. Mccombie, 2007, Bioorganic & medicinal chemistry letters.

Dual binding site inhibitors of B-RAF kinase.

Jianmei Wei, L. Karlsson, J. Edwards, 2008, Bioorganic & medicinal chemistry letters.

A novel B-RAF inhibitor blocks interleukin-8 (IL-8) synthesis in human melanoma xenografts, revealing IL-8 as a potential pharmacodynamic biomarker

Jianmei Wei, L. Karlsson, J. Edwards, 2008, Molecular Cancer Therapeutics.

Inhibitors of farnesyl protein transferase. Synthesis and biological activity of amide and cyanoguanidine derivatives containing a 5,11-dihydro[1]benzthiepin, benzoxepin, and benzazepin [4,3-b]pyridine ring system.

W. R. Bishop, P. Kirschmeier, J. Weinstein, 1998, Bioorganic & medicinal chemistry letters.

Triaryl bis-sulfones as cannabinoid-2 receptor ligands: SAR studies.

Jie Wu, C. Lunn, N. Shih, 2005, Bioorganic & medicinal chemistry letters.

6-Substituted quinolines as RORγt inverse agonists.

J. Edwards, J. Spurlino, M. Cummings, 2017, Bioorganic & medicinal chemistry letters.

Synthesis and evaluation of pyrazolo[3,4-b]quinoline ribofuranosides and their derivatives as inhibitors of oncogenic Ras

P. Kirschmeier, A. McPhail, J. Kelly, 1996 .

Analogues of 1-(3,10-dibromo-8-chloro-6,11-dihydro-5H-benzo-[5,6]-cyclohepta [1,2-b]pyridin-11-yl)piperidine as inhibitors of farnesyl protein transferase.

W. R. Bishop, T. Guzi, A. Nomeir, 1999, Bioorganic & medicinal chemistry.

Synthesis of isomeric 3-piperidinyl and 3-pyrrolidinyl benzo[5,6]cyclohepta[1,2-b]pyridines: sulfonamido derivatives as inhibitors of Ras prenylation.

W. R. Bishop, A. McPhail, L. James, 1998, Bioorganic & medicinal chemistry.

Identification and structure activity relationships of quinoline tertiary alcohol modulators of RORγt.

J. Edwards, J. Spurlino, M. Cummings, 2017, Bioorganic & medicinal chemistry letters.

Pyrrolidino-tetrahydroisoquinolines as potent dual H3 antagonist and serotonin transporter inhibitors.

Sandy J. Wilson, T. Lovenberg, N. Carruthers, 2007, Bioorganic & medicinal chemistry letters.

Pyrrolidino-tetrahydroisoquinolines as potent dual H3 antagonist and serotonin transporter inhibitors.

Sandy J. Wilson, T. Lovenberg, N. Carruthers, 2007, Bioorganic & medicinal chemistry letters.

Novel pyrazole derivatives as potent inhibitors of type II topoisomerases. Part 1: synthesis and preliminary SAR analysis.

John J. M. Wiener, Cheryl A. Grice, M. Hack, 2007, Bioorganic & medicinal chemistry letters.

New Sequential Carbon-Carbon Bond Forming Reactions. A Samarium(II) Iodide Mediated Vinylogous Barbier Reaction Followed by an Aldol Reaction

D. Curran, R. Wolin, 1991 .

Electroreductive cyclization reactions. Stereoselection, creation of quaternary centers in bicyclic frameworks, and a formal total synthesis of quadrone.

R. Little, R. Wolin, C. G. Sowell, 1990 .

Electroreductive cyclization. Ketones and aldehydes tethered to .alpha.,.beta.-unsaturated esters (nitriles). Fundamental investigations

L. Moens, R. Little, R. Dannecker, 1988 .

Novel glycine transporter type-2 reuptake inhibitors. Part 1: alpha-amino acid derivatives.

Sandy J. Wilson, T. Lovenberg, A. Santillán, 2004, Bioorganic & medicinal chemistry.

Novel glycine transporter type-2 reuptake inhibitors. Part 2: beta- and gamma-amino acid derivatives.

Sandy J. Wilson, T. Lovenberg, A. Santillán, 2004, Bioorganic & medicinal chemistry.

Discovery and SAR of 6-alkyl-2,4-diaminopyrimidines as histamine H₄ receptor antagonists.

R. Thurmond, J. Edwards, M. Hack, 2014, Journal of medicinal chemistry.

Pharmacological characterization of oxime agonists of the histamine h 4 receptor

P. Desai, R. Thurmond, L. Karlsson, 2009 .

Novel H3 receptor antagonists. Sulfonamide homologs of histamine.

J. Hey, M. Connolly, R. West, 1998, Bioorganic & Medicinal Chemistry Letters.

Novel H3 Receptor Antagonists. Sulfonamide Homologues of Histamine.

J. Hey, M. Connolly, R. West, 1999 .

(+)-4-[2-[4-(8-Chloro-3,10-dibromo-6,11-dihydro-5H-benzo[5, 6]cyclohepta[1,2-b]- pyridin-11(R)-yl)-1-piperidinyl]-2-oxo-ethyl]-1-piperidinecarboxamid e (SCH-66336): a very potent farnesyl protein transferase inhibitor as a novel antitumor agent.

W. R. Bishop, P. Kirschmeier, L. Wang, 1998, Journal of medicinal chemistry.

Inhibitors of the glycine transporter type-2 (GlyT-2): synthesis and biological activity of benzoylpiperidine derivatives.

T. Lovenberg, Charles Q. Huang, A. Santillán, 2004, Bioorganic & medicinal chemistry.