Y. Saitoh

发表

Super-highly hydroxylated fullerene derivative protects human keratinocytes from UV-induced cell injuries together with the decreases in intracellular ROS generation and DNA damages.

N. Miwa, H. Aoshima, Y. Saitoh, 2011, Journal of photochemistry and photobiology. B, Biology.

Fullerene-C60 incorporated in liposome exerts persistent hydroxyl radical-scavenging activity and cytoprotection in UVA/B-irradiated keratinocytes.

N. Miwa, H. Aoshima, Y. Saitoh, 2011, Journal of nanoscience and nanotechnology.

Clinical evaluation of fullerene-C60 dissolved in squalane for anti-wrinkle cosmetics.

N. Miwa, H. Aoshima, Y. Saitoh, 2010, Journal of Nanoscience and Nanotechnology.

Fullerene-C60/liposome complex: Defensive effects against UVA-induced damages in skin structure, nucleus and collagen type I/IV fibrils, and the permeability into human skin tissue.

N. Miwa, H. Aoshima, Y. Saitoh, 2010, Journal of photochemistry and photobiology. B, Biology.

Highly hydroxylated or gamma-cyclodextrin-bicapped water-soluble derivative of fullerene: the antioxidant ability assessed by electron spin resonance method and beta-carotene bleaching assay.

N. Miwa, H. Aoshima, Y. Saitoh, 2009, Bioorganic & medicinal chemistry letters.

Repressive effects of a capacitive-resistive electric transfer (CRet) hyperthermic apparatus combined with provitamin C on intracellular lipid-droplets formation in adipocytes

N. Miwa, Y. Saitoh, S. Kato, 2013, International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group.

Oleic acid promotes adaptability against oxidative stress in 3T3-L1 cells through lipohormesis

N. Miwa, Y. Saitoh, T. Fujita, 2013, Molecular and Cellular Biochemistry.

Anticancer effects of 6-o-palmitoyl-ascorbate combined with a capacitive-resistive electric transfer hyperthermic apparatus as compared with ascorbate in relation to ascorbyl radical generation

N. Miwa, R. Asada, Y. Saitoh, 2011, Cytotechnology.

The effect of squalane-dissolved fullerene-C60 on adipogenesis-accompanied oxidative stress and macrophage activation in a preadipocyte-monocyte co-culture system.

Li Xiao, N. Miwa, H. Aoshima, 2010, Biomaterials.

Comments to the article “Artefacts with ascorbate and other redox-active compounds in cell culture: epigenetic modifications, and cell killing due to hydrogen peroxide generation in cell culture media”

Y. Saitoh, 2018, Free radical research.

Electrolytically generated hydrogen warm water cleanses the keratin-plug-clogged hair-pores and promotes the capillary blood-streams, more markedly than normal warm water does

Yoshiharu Tanaka, N. Miwa, Y. Saitoh, 2018, Medical gas research.

High-dose ascorbic acid induces carcinostatic effects through hydrogen peroxide and superoxide anion radical generation-induced cell death and growth arrest in human tongue carcinoma cells

Y. Saitoh, Ryouhei Ohwada, Y. Ozeki, 2017, Free radical research.

Administration with telomeric DNA telomere-like oligonucleotides induces enhancement of telomerase activity and resistance against oxidative stress in telomere reverse transcriptase gene-transfected human fibroblasts.

M. Namba, N. Miwa, Shin‐ichi Watanabe, 2010, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Highly hydroxylated fullerene localizes at the cytoskeleton and inhibits oxidative stress in adipocytes and a subcutaneous adipose-tissue equivalent.

Li Xiao, N. Miwa, H. Aoshima, 2011, Free radical biology & medicine.

Transient generation of hydrogen peroxide is responsible for carcinostatic effects of hydrogen combined with platinum nanocolloid, together with increases intracellular ROS, DNA cleavages, and proportion of G2/M-phase

N. Miwa, Y. Saitoh, Minoru Ikeshima, 2016, Free radical research.

Senescence-induced increases in intracellular oxidative stress and enhancement of the need for ascorbic acid in human fibroblasts

N. Miwa, Y. Saitoh, Aiko Morishita, 2013, Molecular and Cellular Biochemistry.

Effects of Platinum Nanocolloid in Combination with Gamma Irradiation on Normal Human Esophageal Epithelial Cells.

Yoshiharu Tanaka, Qiang Li, N. Miwa, 2016, Journal of nanoscience and nanotechnology.

Polyhydroxylated fullerene C60(OH)44 suppresses intracellular lipid accumulation together with repression of intracellular superoxide anion radicals and subsequent PPARγ2 expression during spontaneous differentiation of OP9 preadipocytes into adipocytes

Li Xiao, N. Miwa, Y. Saitoh, 2012, Molecular and Cellular Biochemistry.

Novel polyhydroxylated fullerene suppresses intracellular oxidative stress together with repression of intracellular lipid accumulation during the differentiation of OP9 preadipocytes into adipocytes

Li Xiao, N. Miwa, H. Aoshima, 2010, Free radical research.

Fucoidan-Vitamin C complex suppresses tumor invasion through the basement membrane, with scarce injuries to normal or tumor cells, via decreases in oxidative stress and matrix metalloproteinases.

N. Miwa, Y. Nagai, Y. Saitoh, 2009, International journal of oncology.

Neutral pH hydrogen-enriched electrolyzed water achieves tumor-preferential clonal growth inhibition over normal cells and tumor invasion inhibition concurrently with intracellular oxidant repression.

Li Xiao, N. Miwa, Y. Saitoh, 2008, Oncology research.

Repressive effects of oat extracts on intracellular lipid-droplet formation in adipocytes and a three-dimensional subcutaneous adipose tissue model.

N. Miwa, Y. Kato, Y. Saitoh, 2015, Materials science & engineering. C, Materials for biological applications.

Combined treatment with dissolved hydrogen molecule and platinum nanocolloid exerts carcinostatic/carcinocidal effects by increasing hydrogen peroxide generation and cell death in the human gastric cancer cell line NUGC-4

Y. Saitoh, Minoru Ikeshima, Naho Kawasaki, 2021, Free radical research.

Cytoprotection of vascular endotheliocytes by phosphorylated ascorbate through suppression of oxidative stress that is generated immediately after post‐anoxic reoxygenation or with alkylhydroperoxides

N. Miwa, Y. Saitoh, 2004, Journal of cellular biochemistry.

Resveratrol potentiates intracellular ascorbic acid enrichment through dehydroascorbic acid transport and/or its intracellular reduction in HaCaT cells

Y. Saitoh, Taiki Umezaki, Nene Yonekura, 2020, Molecular and Cellular Biochemistry.

The influence of cellular senescence on intracellular vitamin C transport, accumulation, and function

T. Akiyama, Y. Saitoh, Atsushi Nakawa, 2018, Molecular and Cellular Biochemistry.

Carcinostatic effects of alkanoyl ascorbate plus platinum nano-colloid and stabilization of the esterolytically resultant ascorbate by hydrogen

N. Miwa, Y. Saitoh, S. Kato, 2021, Human Cell.

Platinum nanocolloid-supplemented hydrogendissolved water inhibits growth of human tongue carcinoma cells preferentially over normal cells.

Y. Saitoh, Y. Yoshimura, K. Nakano, 2009, Experimental oncology.

Antitumor and anti-invasive effects of diverse musk-fragrant macrocyclic ketones and their enhancement by hyperthermia.

N. Miwa, R. Asada, Y. Saitoh, 2011, Molecular medicine reports.

Anti‐apoptotic defense of bcl‐2 gene against hydroperoxide‐induced cytotoxicity together with suppressed lipid peroxidation, enhanced ascorbate uptake, and upregulated Bcl‐2 protein

N. Miwa, R. Ouchida, Y. Saitoh, 2003, Journal of cellular biochemistry.

Fish collagen-containing drink is subcutaneously absorbed and attenuates the UVA-induced tissue-integrity destruction and DNA damages in 3D-human skin tissue model

N. Miwa, Y. Saitoh, S. Kato, 2011 .

Carcinostatic effects of diverse ascorbate derivatives in comparison with aliphatic chain moiety structures: Promotion by combined hyperthermia and reduced cytotoxicity to normal cells.

N. Miwa, R. Asada, Y. Saitoh, 2012, Oncology letters.

Resveratrol potentiates intracellular ascorbic acid enrichment through dehydroascorbic acid transport and/or its intracellular reduction in HaCaT cells

Y. Saitoh, Taiki Umezaki, Nene Yonekura, 2020, Molecular and Cellular Biochemistry.

Cytoprotective effects of the lipoidic‐liquiform pro‐vitamin C tetra‐isopalmitoyl‐ascorbate (VC‐IP) against ultraviolet‐A ray‐induced injuries in human skin cells together with collagen retention, MMP inhibition and p53 gene repression

Li Xiao, N. Miwa, Y. Saitoh, 2009, Journal of cellular biochemistry.

Biological safety of neutral-pH hydrogen-enriched electrolyzed water upon mutagenicity, genotoxicity and subchronic oral toxicity

N. Miwa, M. Nakajima, Y. Saitoh, 2010, Toxicology and industrial health.

Effects of hydrogen-rich water bath on visceral fat and skin blotch, with boiling-resistant hydrogen bubbles

N. Miwa, R. Asada, Y. Saitoh, 2019, Medical gas research.

Defensive effects of fullerene-C60/liposome complex against UVA-induced intracellular reactive oxygen species generation and cell death in human skin keratinocytes HaCaT, associated with intracellular uptake and extracellular excretion of fullerene-C60.

Shinya Kato, N. Miwa, Hisae Aoshima, 2010, Journal of photochemistry and photobiology. B, Biology.

Apoptosis prevention in neuronally differentiated PC 12 cells , by bcl-2 gene transfection in the non-proliferative and differentiated state , with retention of neuron-specific proteins and blockage of mitocondrion-relayed apoptotic pathway

S. Yanada, N. Miwa, Y. Saitoh, 2011 .

Bcl‐2 prevents hypoxia/reoxygenation‐induced cell death through suppressed generation of reactive oxygen species and upregulation of Bcl‐2 proteins

N. Miwa, R. Ouchida, Y. Saitoh, 2003, Journal of cellular biochemistry.

Transfection of the anti-apoptotic gene bcl-2 inhibits oxidative stress-induced cell injuries through delaying of NF-!B activation

Y. Kaneda, S. Yanada, N. Miwa, 2006 .

Cytoprotection by bcl‐2 gene transfer against ischemic liver injuries together with repressed lipid peroxidation and increased ascorbic acid in livers and serum

Y. Kaneda, S. Yanada, Y. Saitoh, 2004, Journal of cellular biochemistry.

Photodynamic anti-cancer effects of fullerene [C60]–PEG complex on fibrosarcomas preferentially over normal fibroblasts in terms of fullerene uptake and cytotoxicity

N. Miwa, R. Asada, Y. Saitoh, 2014, Molecular and Cellular Biochemistry.

Moderately controlled transport of ascorbate into aortic endothelial cells against slowdown of the cell cycle, decreasing of the concentration or increasing of coexistent glucose as compared with dehydroascorbate

T. Yamane, N. Nagao, N. Miwa, 1997, Molecular and Cellular Biochemistry.

Antitumor effects of nano-bubble hydrogen-dissolved water are enhanced by coexistent platinum colloid and the combined hyperthermia with apoptosis-like cell death.

N. Miwa, M. Kimura, R. Asada, 2010, Oncology reports.

Li Xiao, N. Miwa, Y. Saitoh, 2012, Molecular and Cellular Biochemistry.

alpha-tocopheryl phosphate suppresses tumor invasion concurrently with dynamic morphological changes and delocalization of cortactin from invadopodia.

N. Miwa, Atsushi Yumoto, Y. Saitoh, 2009, International journal of oncology.

Hydrogen-rich electrolyzed warm water represses wrinkle formation against UVA ray together with type-I collagen production and oxidative-stress diminishment in fibroblasts and cell-injury prevention in keratinocytes.

N. Miwa, Y. Saitoh, S. Kato, 2012, Journal of photochemistry and photobiology. B, Biology.

Carcinostatic effects of alkanoyl ascorbate plus platinum nano-colloid and stabilization of the esterolytically resultant ascorbate by hydrogen

N. Miwa, Y. Saitoh, S. Kato, 2021, Human Cell.

Protective effects of polyvinylpyrrolidone-wrapped fullerene against intermittent ultraviolet-A irradiation-induced cell injury in HaCaT cells.

H. Ohta, Y. Saitoh, Sayuri Hyodo, 2016, Journal of photochemistry and photobiology. B, Biology.

Hydrogen-bubbled platinum-colloid suppresses human esophagus- or tongue-carcinoma cells with intracellular platinum-uptake and the diminished normal-cell mortality

N. Miwa, Y. Saitoh, S. Kato, 2020, Human Cell.

Protective effects of dissolved molecular hydrogen against hydrogen peroxide-, hydroperoxide-, and glyoxal-induced injuries to human skin keratinocytes

Yuuki Yamaguchi, Y. Saitoh, Yuhei Okada, 2021, Molecular and Cellular Biochemistry.

Safety evaluation of highly purified fullerenes (HPFs): based on screening of eye and skin damage.

Shinobu Ito, N. Miwa, Hisae Aoshima, 2009, The Journal of toxicological sciences.

The influence of cellular senescence on intracellular vitamin C transport, accumulation, and function

T. Akiyama, Y. Saitoh, Atsushi Nakawa, 2018, Molecular and Cellular Biochemistry.

Senescence-induced increases in intracellular oxidative stress and enhancement of the need for ascorbic acid in human fibroblasts

N. Miwa, Y. Saitoh, Aiko Morishita, 2013, Molecular and Cellular Biochemistry.

Resveratrol Oligosaccharide Induces mRNA Expression for SIRT

K. Shimoda, H. Hamada, Y. Saitoh, 2018 .

Carcinostatic effects of platinum nanocolloid combined with gamma irradiation on human esophageal squamous cell carcinoma.

Yoshiharu Tanaka, Qiang Li, N. Miwa, 2015, Life sciences.

Colloidal platinum in hydrogen-rich water exhibits radical-scavenging activity and improves blood fluidity.

N. Miwa, Y. Saitoh, S. Kato, 2012, Journal of nanoscience and nanotechnology.

Biological safety of LipoFullerene composed of squalane and fullerene-C60 upon mutagenesis, photocytotoxicity, and permeability into the human skin tissue.

Shinya Kato, N. Miwa, Hisae Aoshima, 2009, Basic & clinical pharmacology & toxicology.

Protective Effects of Polyvinylpyrrolidone-Wrapped Fullerene Against Nitric Oxide/Peroxynitrite-Induced Cellular Injury in Human Skin Keratinocytes.

Asuka Tanaka, Y. Saitoh, Sayuri Hyodo, 2021, Journal of nanoscience and nanotechnology.

Fullerene–polyvinylpyrrolidone clathrate localizes in the cytoplasm to prevent Ultraviolet‐A ray‐induced DNA‐fragmentation and activation of the transcriptional factor NF‐kappaB

Li Xiao, N. Miwa, H. Aoshima, 2010, Journal of cellular biochemistry.

Hydrogen-Nano-Bubble-Rich Water in Bucket/Bathtub Improves Intractable Skin Roughness

N. Miwa, Y. Saitoh, Y. Takada, 2023, Hydrogen.

Suppressive effects of phosphorylated ascorbate on ultraviolet B radiation-induced DNA damage and differential expression of the wild-type and mutated p53 tumor-suppressor gene in keratinocytes.

M. Ichihashi, N. Miwa, M. Sugimoto, 2009, Molecular medicine reports.

Molecular hydrogen suppresses Porphyromonas gingivalis lipopolysaccharide-induced increases in interleukin-1 alpha and interleukin-6 secretion in human gingival cells

A. Matsumoto, Y. Saitoh, Daigo Matsuoka, 2021, Molecular and Cellular Biochemistry.

Molecular hydrogen suppresses Porphyromonas gingivalis lipopolysaccharide-induced increases in interleukin-1 alpha and interleukin-6 secretion in human gingival cells

Y. Saitoh, Daigo Matsuoka, Nene Yonekura, 2021, Molecular and Cellular Biochemistry.

Novel polyhydroxylated fullerene suppresses intracellular oxidative stress together with repression of intracellular lipid accumulation during the differentiation of OP9 preadipocytes into adipocytes

Li Xiao, N. Miwa, H. Aoshima, 2010, Free radical research.

Defensive effects of fullerene-C60 dissolved in squalane against the 2,4-nonadienal-induced cell injury in human skin keratinocytes HaCaT and wrinkle formation in 3D-human skin tissue model.

N. Miwa, H. Aoshima, Y. Saitoh, 2010, Journal of biomedical nanotechnology.

Biological safety of liposome-fullerene consisting of hydrogenated lecithin, glycine soja sterols, and fullerene-C60 upon photocytotoxicity and bacterial reverse mutagenicity

H. Aoshima, S Kato, H Aoshima, 2009, Toxicology and industrial health.

N. Miwa, Y. Saitoh, S. Kato, 2012, Journal of photochemistry and photobiology. B, Biology.

Li Xiao, N. Miwa, Y. Saitoh, 2009, Journal of cellular biochemistry.

Anticancer effects of fullerene [C60] included in polyethylene glycol combined with visible light irradiation through ROS generation and DNA fragmentation on fibrosarcoma cells with scarce cytotoxicity to normal fibroblasts.

N. Miwa, Yasukazu Saitoh, Nobuhiko Miwa, 2011, Oncology research.