C. Rath

发表

Biocatalytic synthesis of pikromycin, methymycin, neomethymycin, novamethymycin, and ketomethymycin.

Alison R. H. Narayan, D. Sherman, Y. Yoon, 2013, Journal of the American Chemical Society.

Acyl-CoA subunit selectivity in the pikromycin polyketide synthase PikAIV: steady-state kinetics and active-site occupancy analysis by FTICR-MS.

K. Reynolds, D. Sherman, K. Håkansson, 2011, Chemistry & biology.

Structural and functional analysis of AsbF: Origin of the stealth 3,4-dihydroxybenzoic acid subunit for petrobactin biosynthesis

Brian F. Pfleger, N. Bergman, A. Joachimiak, 2008, Proceedings of the National Academy of Sciences.

Optimization of CoaD Inhibitors against Gram-Negative Organisms through Targeted Metabolomics.

Brian Y Feng, Lisha Wang, Mei Geng, 2017, ACS infectious diseases.

Interplay of Klebsiella pneumoniae fabZ and lpxC Mutations Leads to LpxC Inhibitor-Dependent Growth Resulting from Loss of Membrane Homeostasis

Lisha Wang, C. Dean, A. Ruzin, 2018, mSphere.

Biochemical and structural characterization of the tautomycetin thioesterase: analysis of a stereoselective polyketide hydrolase.

Janet L. Smith, D. Sherman, D. Akey, 2010, Angewandte Chemie.

Biochemical and structural characterization of germicidin synthase: analysis of a type III polyketide synthase that employs acyl-ACP as a starter unit donor.

Janet L. Smith, G. Chlipala, D. Sherman, 2012, Journal of the American Chemical Society.

NRPS/PKS hybrid enzymes and their natural products

D. Sherman, J. D. Kittendorf, Jeffrey D. Kittendorf, 2010 .

Structures and cytotoxic properties of trichoverroids and their macrolide analogues produced by saltwater culture of Myrothecium verrucaria.

F. Valeriote, P. Crews, K. Tenney, 2003, Journal of medicinal chemistry.

Toxic Accumulation of LPS Pathway Intermediates Underlies the Requirement of LpxH for Growth of Acinetobacter baumannii ATCC 19606

C. Dean, D. Richie, Jun-Rong Wei, 2016, PloS one.

Chemoenzymatic synthesis of cryptophycin anticancer agents by an ester bond-forming non-ribosomal peptide synthetase module.

D. Sherman, K. Håkansson, Yousong Ding, 2011, Journal of the American Chemical Society.

Structure-guided enzymology of the lipid A acyltransferase LpxM reveals a dual activity mechanism

Qijun Hu, M. Knapp, S. Shia, 2016, Proceedings of the National Academy of Sciences.

Characterization of an Acinetobacter baumannii lptD Deletion Strain: Permeability Defects and Response to Inhibition of Lipopolysaccharide and Fatty Acid Biosynthesis

C. Dean, Qijun Hu, D. Richie, 2015, Journal of bacteriology.

Biosynthetic principles in marine natural product systems

D. Sherman, J. D. Kittendorf, Jeffrey D. Kittendorf, 2012 .

Rapid analysis of protein expression and solubility with the SpyTag-SpyCatcher system.

William S. Sawyer, C. Rath, L. Metzger, 2016, Protein expression and purification.

Two distinct mechanisms of small molecule inhibition of LpxA acyltransferase essential for lipopolysaccharide biosynthesis

C. Ho, M. Li, S. Subramanian, 2019, bioRxiv.

Assessing Antibiotic Permeability of Gram-Negative Bacteria via Nanofluidics.

Luke P. Lee, SoonGweon Hong, P. Lee, 2017, ACS nano.

In vivo and in vitro trans-acylation by BryP, the putative bryostatin pathway acyltransferase derived from an uncultured marine symbiont.

David H Sherman, Kristina Håkansson, Christopher M Thomas, 2008, Chemistry & biology.

Meta-omic characterization of the marine invertebrate microbial consortium that produces the chemotherapeutic natural product ET-743.

Hye Kyong Kweon, Robert M. Williams, D. Sherman, 2011, ACS chemical biology.

LpxK Is Essential for Growth of Acinetobacter baumannii ATCC 19606: Relationship to Toxic Accumulation of Lipid A Pathway Intermediates

C. Dean, D. Richie, Jun-Rong Wei, 2017, mSphere.

Polyketide β-branching in bryostatin biosynthesis: identification of surrogate acetyl-ACP donors for BryR, an HMG-ACP synthase.

D. Sherman, K. Håkansson, C. Rath, 2010, Chemistry & biology.

SSHSH O ATKS TEACP module 6 end PikAIV SHSH OH ATKS TEACP module 6 end PikAIV SSH OH ATKS TEACP module 6 end PikAIV OH ATKS TEACP module 6 end PikAIV

K. Reynolds, D. Sherman, K. Håkansson, 2011 .

In vivo and in vitro trans-acylation by BryP, the putative bryostatin pathway acyltransferase derived from an uncultured marine symbiont.

Christopher M Thomas, D. Sherman, K. Håkansson, 2008, Chemistry & biology.