E. Tonner

发表

Suppression of epithelial apoptosis and delayed mammary gland involution in mice with a conditional knockout of Stat3.

S. Akira, D. Flint, C. Watson, 1999, Genes & development.

The role of Stat3 in apoptosis and mammary gland involution. Conditional deletion of Stat3.

S. Akira, D. Flint, C. Watson, 2000, Advances in experimental medicine and biology.

IGFBP-5 enhances epithelial cell adhesion and protects epithelial cells from TGFβ1-induced mesenchymal invasion.

J. Beattie, D. Flint, J. Edwards, 2013, The international journal of biochemistry & cell biology.

Relative Roles of TGF-β and IGFBP-5 in Idiopathic Pulmonary Fibrosis

D. Flint, A. Sureshbabu, G. Allan, 2011, Pulmonary medicine.

Insulin-Like Growth Factor Binding Proteins: IGF-Dependent and -Independent Effects in the Mammary Gland

D. Flint, G. Allan, E. Tonner, 2004, Journal of Mammary Gland Biology and Neoplasia.

The role of prolactin and growth hormone in the regulation of casein gene expression and mammary cell survival: relationships to milk synthesis and secretion.

D. Flint, L. Quarrie, C. Wilde, 1996, Endocrinology.

Amino acids within the extracellular matrix (ECM) binding region (201-218) of rat insulin-like growth factor binding protein (IGFBP)-5 are important determinants in binding IGF-I.

J. Beattie, D. Flint, H. Song, 1999, Journal of molecular endocrinology.

Effects of a polyclonal antiserum to rat growth hormone on circulating insulin-like growth factor (IGF)-I and IGF-binding protein concentrations and the growth of muscle and bone.

D. Flint, B. Thomson, N. Loveridge, 1994, The Journal of endocrinology.

Insulin-like growth factor binding proteins and mammary gland development.

D. Flint, A. Sureshbabu, E. Tonner, 2011, The International journal of developmental biology.

Control of mammary involution by insulin-like growth factor binding proteins: role of prolactin

D. Flint, C. Whitelaw, C. Knight, 2001 .

Insulin-like growth factor binding protein-5 (IGFBP-5) potentially regulates programmed cell death and plasminogen activation in the mammary gland.

D. Flint, L. Shkreta, C. Whitelaw, 2000, Advances in experimental medicine and biology.

Insulin-like growth factor binding proteins initiate cell death and extracellular matrix remodeling in the mammary gland.

J. Beattie, D. Flint, W. Hurley, 2005, Domestic animal endocrinology.

Several insulin-like growth factor-I analogues and complexes of insulin-like growth factors-I and -II with insulin-like growth factor-binding protein-3 fail to mimic the effect of growth hormone upon lactation in the rat.

J. Beattie, D. Flint, E. Tonner, 1994, The Journal of endocrinology.

Regulation of Apoptosis in Cultured Mammary Epithelial Cells

D. Flint, L. Quarrie, C. Wilde, 1997 .

Growth hormone, acting in part through the insulin-like growth factor axis, rescues developmental, but not metabolic, activity in the mammary gland of mice expressing a single allele of the prolactin receptor.

J. Shand, D. Flint, P. Kelly, 2002, Endocrinology.

IGFBP-5 induces epithelial and fibroblast responses consistent with the fibrotic response.

J. Shand, J. Beattie, D. Flint, 2009, Biochemical Society transactions.

Production of insulin-like growth factor binding protein (IGFBP), IGFBP-3 protease, and expression of IGF-I receptors by cells of the sheep immune system.

J. Beattie, D. Flint, E. Tonner, 1995, European journal of endocrinology.

Investigation of the mechanism of action of growth hormone in stimulating lactation in the rat.

J. Beattie, D. Flint, E. Tonner, 1992, The Journal of endocrinology.

A novel role for IRF-1 as a suppressor of apoptosis

D. Flint, C. Watson, A. Clarke, 2000, Oncogene.

Does an IGF-binding protein (IGFBP) present in involuting rat mammary gland regulate apoptosis?

D. Flint, L. Quarrie, C. Wilde, 1995, Progress in growth factor research.

Hormonal control of plasmin and tissue-type plasminogen activator activity in rat milk during involution of the mammary gland.

D. Flint, G. Allan, E. Tonner, 2000, The Journal of endocrinology.

Effects of growth hormone and ovariectomy on performance, serum hormones, insulin-like growth factor-binding proteins, and muscle fiber properties of prepubertal Friesian heifers.

D. Flint, M. Vestergaard, K. Sejrsen, 1995, Journal of animal science.

Cumulative mutagenesis of the basic residues in the 201-218 region of insulin-like growth factor (IGF)-binding protein-5 results in progressive loss of both IGF-I binding and inhibition of IGF-I biological action.

Sharon M Kelly, Iain F Gow, James Beattie, 2006, Endocrinology.

IGFBP5 induces cell adhesion, increases cell survival and inhibits cell migration in MCF-7 human breast cancer cells

J. Shand, J. Beattie, D. Flint, 2012, Journal of Cell Science.

Insulin-like growth factor binding protein-5 (IGFBP-5) induces premature cell death in the mammary glands of transgenic mice.

J. Beattie, D. Flint, C. Whitelaw, 2002, Development.

Insulin‐like growth factor binding protein (IGFBP)‐5 is upregulated during both differentiation and apoptosis in primary cultures of mouse mammary epithelial cells

J. Beattie, D. Flint, K. Phillips, 2006, Journal of cellular physiology.

Decreased fat content and increased lean in pigs treated with antibodies to adipocyte plasma membranes.

D. Flint, S. Butterwith, S. Kestin, 1993, Journal of animal science.

D. Flint, A. Logan, E. Tonner, 2022 .

Role of Insulin-Like Growth Factor Binding Proteins in Mammary Gland Development

J. Beattie, D. Flint, G. Allan, 2008, Journal of Mammary Gland Biology and Neoplasia.

Insulin-like Growth Factor-binding Protein-5 Activates Plasminogen by Interaction with Tissue Plasminogen Activator, Independently of Its Ability to Bind to Plasminogen Activator Inhibitor-1, Insulin-like Growth Factor-I, or Heparin*

James Beattie, J. Shand, J. Beattie, 2006, Journal of Biological Chemistry.

Influence of microenvironment on mammary epithelial cell survival in primary culture

D. Flint, L. Quarrie, C. Wilde, 1999, Journal of cellular physiology.

IGFBP-5 induces epithelial and fibroblast responses consistent with the fibrotic response.

J. Shand, J. Beattie, D. Flint, 2009, Biochemical Society transactions.