Yanhao Lai

发表

Resveratrol protects against arsenic trioxide‐induced oxidative damage through maintenance of glutathione homeostasis and inhibition of apoptotic progression

Yuan Liu, Zunzhen Zhang, Xuejun Jiang, 2015, Environmental and molecular mutagenesis.

Dynamic single-cell intracellular pH sensing using a SERS-active nanopipette.

Jin He, Xuewen Wang, Yanhao Lai, 2020, The Analyst.

The role of NF-κB in PARP-inhibitor-mediated sensitization and detoxification of arsenic trioxide in hepatocellular carcinoma cells.

Yang Li, Zunzhen Zhang, Yanhao Lai, 2015, The Journal of toxicological sciences.

Protection of Nrf2 against arsenite‐induced oxidative damage is regulated by the cyclic guanosine monophosphate‐protein kinase G signaling pathway

Yuan Liu, Zunzhen Zhang, Xuejun Jiang, 2017, Environmental toxicology.

R-loops promote trinucleotide repeat deletion through DNA base excision repair enzymatic activities

F. Leng, Yuan Liu, Lata Balakrishnan, 2020, The Journal of Biological Chemistry.

Oxidative DNA Damage Modulates DNA Methylation Pattern in Human Breast Cancer 1 (BRCA1) Gene via the Crosstalk between DNA Polymerase β and a de novo DNA Methyltransferase

Samuel H. Wilson, J. Horton, I. Agoulnik, 2020, Cells.

Bypass of a 5',8-cyclopurine-2'-deoxynucleoside by DNA polymerase β during DNA replication and base excision repair leads to nucleotide misinsertions and DNA strand breaks.

Michael A. Terzidis, A. Masi, C. Chatgilialoglu, 2015, DNA repair.

Tyrosyl-DNA Phosphodiesterase 1 and Topoisomerase I Activities as Predictive Indicators for Glioblastoma Susceptibility to Genotoxic Agents

W. Reinhold, Y. Pommier, Y. Tse‐Dinh, 2019, bioRxiv.

Scanning Ion Conductance Microscopy Study Reveals the Disruption of the Integrity of the Human Cell Membrane Structure by Oxidative DNA Damage.

Jin He, Yuan Liu, J. Hutcheson, 2021, ACS applied bio materials.

Diastereomeric Recognition of 5’,8-cyclo-2’-Deoxyadenosine Lesions by Human Poly(ADP-ribose) Polymerase 1 in a Biomimetic Model

A. Masi, C. Chatgilialoglu, C. Ferreri, 2018, Cells.

A 5′, 8-cyclo-2′-deoxypurine lesion induces trinucleotide repeat deletion via a unique lesion bypass by DNA polymerase β

Michael A. Terzidis, A. Masi, C. Chatgilialoglu, 2014, Nucleic acids research.

AP endonuclease 1 prevents the extension of a T/G mismatch by DNA polymerase β to prevent mutations in CpGs during base excision repair.

Yuan Liu, Zhongliang Jiang, Yanhao Lai, 2016, DNA repair.

Replication Stress and Consequential Instability of the Genome and Epigenome

Yuan Liu, Yanhao Lai, Pawlos S. Tsegay, 2019, Molecules.

N6-methyladenosine mediates arsenite-induced human keratinocyte transformation by suppressing p53 activation.

Yuan Liu, Tianhe Zhao, Donglei Sun, 2020, Environmental pollution.

Androgen Receptor and Poly(ADP-ribose) Glycohydrolase Inhibition Increases Efficiency of Androgen Ablation in Prostate Cancer Cells

I. Agoulnik, D. Ogilvie, I. Waddell, 2020, Scientific Reports.

Inhibition of base excision repair by natamycin suppresses prostate cancer cell proliferation.

I. Agoulnik, Y. Tse‐Dinh, Yuan Liu, 2019, Biochimie.

Base Excision Repair of Chemotherapeutically-Induced Alkylated DNA Damage Predominantly Causes Contractions of Expanded GAA Repeats Associated with Friedreich's Ataxia

I. Agoulnik, Yuan Liu, Zunzhen Zhang, 2014, PloS one.

Crosstalk between MSH2–MSH3 and polβ promotes trinucleotide repeat expansion during base excision repair

C. McMurray, Helen Budworth, Yuan Liu, 2016, Nature Communications.

Base excision repair of oxidative DNA damage coupled with removal of a CAG repeat hairpin attenuates trinucleotide repeat expansion

Yanbin Zhang, Yuan Liu, Zunzhen Zhang, 2014, Nucleic acids research.

Brevetoxin‐2, is a unique inhibitor of the C‐terminal redox center of mammalian thioredoxin reductase‐1

Yuan Liu, K. Rein, Wei Chen, 2017, Toxicology and applied pharmacology.

Crosstalk between MSH2–MSH3 and polβ promotes trinucleotide repeat expansion during base excision repair

C. McMurray, Helen Budworth, Yuan Liu, 2016, Nature Communications.

Instability of CTG Repeats is Governed by the Position of a DNA Base Lesion through Base Excision Repair

Yuan Liu, Zunzhen Zhang, Yanhao Lai, 2013, PloS one.

Involvement of DNA polymerase β overexpression in the malignant transformation induced by benzo[a]pyrene.

Yuan Liu, Mei Wu, Zunzhen Zhang, 2013, Toxicology.

Deregulated expression of DNA polymerase β is involved in the progression of genomic instability

Yuan Liu, Mei Wu, Zunzhen Zhang, 2012, Environmental and molecular mutagenesis.

Role of DNA polymerase beta in the genotoxicity of arsenic

Mei Wu, Zunzhen Zhang, Wei Zhao, 2011, Environmental and molecular mutagenesis.

Links between DNA polymerase beta expression and sensitivity to bleomycin.

Mei Wu, Zunzhen Zhang, Wei Zhao, 2011, Toxicology.

Antioxidant activities of Ganoderma lucidum polysaccharides and their role on DNA damage in mice induced by cobalt-60 gamma-irradiation.

Mei Wu, Zunzhen Zhang, Wei Zhao, 2012, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Proliferating cell nuclear antigen prevents trinucleotide repeat expansions by promoting repeat deletion and hairpin removal.

Yuan Liu, Yanhao Lai, Jill M. Beaver, 2016, DNA repair.

Modulation of trinucleotide repeat instability by DNA polymerase β polymorphic variant R137Q

Yuan Liu, Yanhao Lai, R. Lei, 2017, PloS one.

AP endonuclease 1 prevents trinucleotide repeat expansion via a novel mechanism during base excision repair

Yuan Liu, Yanhao Lai, A. Casin, 2015, Nucleic acids research.

miR-155 mediates arsenic trioxide resistance by activating Nrf2 and suppressing apoptosis in lung cancer cells

Yuan Liu, Hongyu Chen, Zunzhen Zhang, 2017, Scientific Reports.

A partial Drp1 knockout improves autophagy flux independent of mitochondrial function

S. Luo, K. Tieu, J. Richardson, 2023, bioRxiv.

Androgen Receptor and Poly(ADP-ribose) Glycohydrolase Inhibition Increases Efficiency of Androgen Ablation in Prostate Cancer Cells

I. Agoulnik, D. Ogilvie, I. Waddell, 2020, Scientific Reports.

The deoxyribose phosphate lyase of DNA polymerase β suppresses a processive DNA synthesis to prevent trinucleotide repeat instability

Y. Weizmann, Yuan Liu, Yanhao Lai, 2018, Nucleic acids research.

miR-155 mediates arsenic trioxide resistance by activating Nrf2 and suppressing apoptosis in lung cancer cells

Yuan Liu, Hongyu Chen, Zunzhen Zhang, 2017, Scientific Reports.

Trinucleotide repeat instability via DNA base excision repair.

Yuan Liu, Yanhao Lai, Eduardo E. Laverde, 2020, DNA repair.

An oxidized abasic lesion inhibits base excision repair leading to DNA strand breaks in a trinucleotide repeat tract

M. Greenberg, Yuan Liu, Liwei Weng, 2018, PloS one.

Role of DNA polymerase beta in the genotoxicity of arsenic

Mei Wu, Zunzhen Zhang, Wei Zhao, 2011, Environmental and molecular mutagenesis.

Involvement of DNA polymerase β overexpression in the malignant transformation induced by benzo[a]pyrene.

Yuan Liu, Mei Wu, Zunzhen Zhang, 2013, Toxicology.

Deregulated expression of DNA polymerase β is involved in the progression of genomic instability

Yuan Liu, Mei Wu, Zunzhen Zhang, 2012, Environmental and Molecular Mutagenesis.

Crosstalk between MSH2–MSH3 and polβ promotes trinucleotide repeat expansion during base excision repair

Helen Budworth, Yuan Liu, Zunzhen Zhang, 2016, Nature Communications.

Obesity increases genomic instability at DNA repeat-mediated endogenous mutation hotspots

Guliang Wang, Yuan Liu, Yanhao Lai, 2024, Nature communications.