R. Alexander

发表

Towards tumour targeting with copper-radiolabelled macrocycle–antibody conjugates: synthesis, antibody linkage, and complexation behaviour

M. Eaton, R. Kataky, C. Walker, 1990 .

Structure of an allosteric inhibitor of LFA-1 bound to the I-domain studied by crystallography, NMR, and calorimetry.

T. Ceska, L. Spyracopoulos, M. Robinson, 2004, Biochemistry.

AN-nitrosochloroethyl-cephalosporin carbamate prodrug for antibody-directed enzyme prodrug therapy (ADEPT)

J. A. Kraunsoe, A. J. Pratt, R. Alexander, 1996 .

Antibody labelling with functionalised cyclam macrocycles

R. Titmas, M. Eaton, A. Millican, 1988 .

The inhibition of antigen‐induced eosinophilia and bronchoconstriction by CDP840, a novel stereo‐selective inhibitor of phosphodiesterase type 4

R. Owens, M. Merriman, P. Hughes, 1996, British journal of pharmacology.

Correction to Small Molecule Inhibitors of Bromodomain-Acetyl-lysine Interactions.

M. Höss, R. Paton, D. Hewings, 2016, ACS chemical biology.

Investigation of the in vitro metabolism profile of a phosphodiesterase-IV inhibitor, CDP-840: leading to structural optimization.

H. Perrier, J. Yergey, J. Silva, 2001, Drug metabolism and disposition: the biological fate of chemicals.

Cephalosporin Nitrogen Mustard Carbamate prodrugs for “ADEPT”.

N. Beeley, F. Willenbrock, A. J. Pratt, 1991 .

The use of enantiomerically pure ketene dithioacetal bis(sulfoxides) in highly diastereoselective intramolecular nitrone cycloadditions. Application in the total synthesis of the beta-amino acid (-)-cispentacin and the first asymmetric synthesis of cis-(3R,4R)-4-amino-pyrrolidine-3-carboxylic acid.

V. Aggarwal, R. Alexander, S. Roseblade, 2003, Organic & biomolecular chemistry.

4-(1,3-Thiazol-2-yl)morpholine derivatives as inhibitors of phosphoinositide 3-kinase.

M. Batchelor, Andrew Gill, I. Whitcombe, 2008, Bioorganic & medicinal chemistry letters.

Direct measurement of the anomeric effect in sulfoxides: conformationalanalysis and X-ray crystal structures of 2-bromo- and2-chloro-1,3-dithiane trans-1,3-dioxides

B. F. Taylor, H. Adams, V. Aggarwal, 1997 .

2-Halogeno-1,3-dithiane 1,3-dioxide: a diastereoselective carbonyl anionequivalent in reactions with aldehydes

H. Adams, V. Aggarwal, R. Alexander, 1997 .

Alkene carbosulphenylation and carboselenylation: The use of allyltrimethylsilane and o-silylated enolates.

I. Paterson, R. Alexander, 1983 .

Highly diastereoselective nitrone cycloaddition onto a chiral ketene equivalent: asymmetric synthesis of cispentacin.

V. Aggarwal, R. Alexander, S. Roseblade, 2002, Organic letters.

Transition-metal mediated asymmetric synthesis. Part 5. Alternative methods for the formation of tricarbonyl(η5-cyclohexadienyl)iron(1+) salts

G. Stephenson, R. Alexander, 1987 .

Transition–metal mediated asymmetric synthesis. Part 6. Organometallic approaches to the enantiomer synthesis of tridachione: a role for planar chirality in synthesis design

C. Morley, G. Stephenson, R. Alexander, 1988 .

Transition‐Metal Mediated Asymmetric Synthesis. Part 6. Organometallic Approaches to the Enantiomer Synthesis of Tridachione: A Role for Planar Chirality in Synthesis Design.

C. Morley, G. Stephenson, R. Alexander, 1988 .

π-Complexes with Planar Chirality: Control Centers for Stereoselective Synthesis

C. Morley, G. Stephenson, P. Howard, 1989 .

Reversal of regiocontrol in the alkylation of an arene π-complex

G. Stephenson, R. Alexander, 1986 .

A superior method for the addition of cyanide to substituted tricarbonyl(η5-cyclohexadienyl)iron(1+) salts

G. Stephenson, R. Alexander, 1986 .

Reversal of Regiocontrol in the Alkylation of an Arene π-Complex.

G. Stephenson, R. Alexander, 1987 .

Small molecule inhibitors of bromodomain-acetyl-lysine interactions.

M. Höss, R. Paton, D. Hewings, 2015, ACS chemical biology.

CDP840. A prototype of a novel class of orally active anti-inflammatory phosphodiesterase 4 inhibitors.

R. Morphy, B. Mason, R. Allen, 2002, Bioorganic & medicinal chemistry letters.

Achieving multi-isoform PI3K inhibition in a series of substituted 3,4-dihydro-2H-benzo[1,4]oxazines.

T. Ceska, W. Pitt, H. Lightfoot, 2008, Bioorganic & medicinal chemistry letters.

Highly Diastereoselective Epoxidation of Ketene Dithioacetal Dioxides: A New Approach to the Asymmetric Synthesis of alpha-Amino Amides.

V. Aggarwal, R. Alexander, J. Worrall, 1998, Journal of Organic Chemistry.

Highly Diastereoselective Epoxidation of Ketene Dithioacetal Dioxides: A New Approach to the Asymmetric Synthesis of α-Amino Amides.

V. Aggarwal, R. Alexander, J. Worrall, 1999 .

Asymmetric alkylation and sulphenylation of chiral O-silylated imide enolates.

I. Paterson, R. Alexander, 1986 .