C. Dzierba

发表

Ti-Catalyzed Enantioselective Addition of Cyanide to Imines. A Practical Synthesis of Optically Pure α-Amino Acids

Clinton A. Krueger, M. Snapper, A. Hoveyda, 1999 .

Dihydropyridopyrazinones and dihydropteridinones as corticotropin-releasing factor-1 receptor antagonists: structure-activity relationships and computational modeling.

G. Trainor, T. Molski, M. Rafalski, 2007, Journal of medicinal chemistry.

An Ascending Synthesis of Adrenalcorticosteroids. The Total Synthesis of (+)-Adrenosterone

K. Shea, K. Zandi, C. Dzierba, 1996 .

Design, synthesis, and evaluation of phenylglycinols and phenyl amines as agonists of GPR88.

Alan G. E. Wilson, Vijay T. Ahuja, Y. Liu, 2015, Bioorganic & medicinal chemistry letters.

The discovery of potent agonists for GPR88, an orphan GPCR, for the potential treatment of CNS disorders.

Y. Liu, A. Cacace, J. Macor, 2015, Bioorganic & medicinal chemistry letters.

Chapter 1 Recent Advances in Corticotropin-Releasing Factor Receptor Antagonists

J. Bronson, C. Dzierba, R. Hartz, 2008 .

In vitro Characterization of a small molecule inhibitor of the alanine serine cysteine transporter ‐1 (SLC7A10)

J. Macor, A. Hendricson, L. Hunihan, 2014, Journal of neurochemistry.

Chapter 25. Microwave-assisted chemistry as a tool for drug discovery

A. Combs, Carolyn Diane Dzierba, Andrew P. Combs, 2002 .

Discovery of Indole- and Indazole-acylsulfonamides as Potent and Selective NaV1.7 Inhibitors for the Treatment of Pain.

N. Meanwell, J. Herrington, D. Post‐Munson, 2018, Journal of medicinal chemistry.

Synthesis and structure-activity relationships of pyrido[3,2-b]pyrazin-3(4H)-ones and pteridin-7(8H)-ones as corticotropin-releasing factor-1 receptor antagonists.

J. Macor, G. Trainor, H. Wong, 2012, Bioorganic & medicinal chemistry letters.

Bicyclic Heterocyclic Replacement of an Aryl Amide Leading to Potent and Kinase-Selective Adaptor Protein 2-Associated Kinase 1 Inhibitors.

Vijay T. Ahuja, J. Macor, S. E. Kiefer, 2022, Journal of medicinal chemistry.

Inhibition of AAK1 Kinase as a Novel Therapeutic Approach to Treat Neuropathic Pain

Alan G. E. Wilson, G. Shankar, S. Mandlekar, 2016, The Journal of Pharmacology and Experimental Therapeutics.

Parallel synthesis of acylsemicarbazide libraries: preparation of potent cyclin dependent kinase (cdk) inhibitors.

C. Dzierba, D. Nugiel, A. Vidwans, 2004, Bioorganic & medicinal chemistry letters.

Discovery and Optimization of Biaryl Alkyl Ethers as a Novel Class of Highly Selective, CNS-Penetrable, and Orally Active Adaptor Protein-2-Associated Kinase 1 (AAK1) Inhibitors for the Potential Treatment of Neuropathic Pain.

G. Shankar, J. Macor, C. Albright, 2022, Journal of medicinal chemistry.

Discovery, Structure-Activity Relationships, and In Vivo Evaluation of Novel Aryl Amides as Brain Penetrant Adaptor Protein 2-Associated Kinase 1 (AAK1) Inhibitors for the Treatment of Neuropathic Pain.

Vijay T. Ahuja, J. Macor, L. Bristow, 2021, Journal of medicinal chemistry.

Discovery of non-zwitterionic aryl sulfonamides as Nav1.7 inhibitors with efficacy in preclinical behavioral models and translational measures of nociceptive neuron activation.

Andrea Mcclure, Ping Chen, N. Meanwell, 2017, Bioorganic & medicinal chemistry.

Discovery of (S)-1-((2',6-Bis(difluoromethyl)-[2,4'-bipyridin]-5-yl)oxy)-2,4-dimethylpentan-2-amine (BMS-986176/LX-9211): A Highly Selective, CNS Penetrable, and Orally Active Adaptor Protein-2 Associated Kinase 1 Inhibitor in Clinical Trials for the Treatment of Neuropathic Pain.

Alan G. E. Wilson, G. Shankar, J. Macor, 2022, Journal of medicinal chemistry.

Small molecule receptor protein tyrosine phosphatase γ (RPTPγ) ligands that inhibit phosphatase activity via perturbation of the tryptophan-proline-aspartate (WPD) loop.

V. Goldfarb, B. Beno, J. Macor, 2011, Journal of medicinal chemistry.

Development of a Rapid Scale-Up Synthesis of (S)-N-(8-((2-Amino-2,4-dimethylpentyl)oxy)-5H-chromeno[3,4-c]pyridin-2-yl)acetamide, a Potent Adaptor-Associated Kinase 1 Inhibitor

J. Macor, A. Mathur, Jianqing Li, 2022, Organic Process Research & Development.