Fang Liu

发表

Identification, Design and Bio-Evaluation of Novel Hsp90 Inhibitors by Ligand-Based Virtual Screening

Q. You, Meng-Chen Lu, Shengmiao Zhang, 2013, PloS one.

Hybrids of the Benzofuran Core from Natural Products and the 2,4‐Dihydroxy‐5‐isopropylbenzene Fragment as Potent Hsp90 Inhibitors: Design, Synthesis and Bioevaluation

Q. You, Haopeng Sun, Xiaoli Xu, 2014, Molecular informatics.

Discovery and Bioevaluation of Novel Pyrazolopyrimidine Analogs as Competitive Hsp90 Inhibitors Through Shape‐Based Similarity Screening

Q. You, Haopeng Sun, Xiaoli Xu, 2014, Molecular informatics.

Synthesis and evaluation of 4-(2-hydroxypropyl)piperazin-1-yl) derivatives as Hsp90 inhibitors.

Q. You, Haopeng Sun, Xiaoli Xu, 2016, Bioorganic & medicinal chemistry.

CPUY201112, a novel synthetic small-molecule compound and inhibitor of heat shock protein Hsp90, induces p53-mediated apoptosis in MCF-7 cells

Q. You, Meng-Chen Lu, Haopeng Sun, 2016, Scientific Reports.

Novel 5-carboxy-8-HQ based histone demethylase JMJD2A inhibitors: introduction of an additional carboxyl group at the C-2 position of quinoline.

Q. You, J. Zhuang, Dongdong Li, 2015, European journal of medicinal chemistry.

Design, synthesis and biological activity evaluation of novel 2,6-difluorobenzamide derivatives through FtsZ inhibition.

Fang Liu, S. Semple, H. Venter, 2017, Bioorganic & medicinal chemistry letters.

Synthesis and Cytotoxic Activity of Novel C-23-Modified Asiatic Acid Derivatives

Cheng-gang Huang, Ming-cang Chen, Xiaoting Tian, 2020, Molecules.

Identification and optimization of novel Hsp90 inhibitors with tetrahydropyrido[4,3-d]pyrimidines core through shape-based screening.

Hao-Ze Huang, Fang Liu, Xiao-Li Xu, 2014, European journal of medicinal chemistry.

Discovery and Design of Tricyclic Scaffolds as Protein Kinase CK2 (CK2) Inhibitors through a Combination of Shape-Based Virtual Screening and Structure-Based Molecular Modification

Fang Liu, Xiaoli Xu, Xiaowen Wu, 2013, J. Chem. Inf. Model..

Indenoisoquinoline derivatives as topoisomerase I inhibitors that suppress angiogenesis by affecting the HIF signaling pathway.

F. Liu, Yong Yang, Q. You, 2013, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Discovery and Modification of in Vivo Active Nrf2 Activators with 1,2,4-Oxadiazole Core: Hits Identification and Structure-Activity Relationship Study.

Q. You, Meng-Chen Lu, Zhengyu Jiang, 2015, Journal of medicinal chemistry.

Synthesis and evaluation of (±)-dunnione and its ortho-quinone analogues as substrates for NAD(P)H:quinone oxidoreductase 1 (NQO1).

Q. You, Jinlei Bian, Haopeng Sun, 2015, Bioorganic & medicinal chemistry letters.

Identification of novel JMJD2A inhibitor scaffold using shape and electrostatic similarity search combined with docking method and MM-GBSA approach

Fang Liu, Q. You, Dongdong Li, 2015 .

Novel Tetrahydropyrido[4,3-d]pyrimidines as Potent Inhibitors of Chaperone Heat Shock Protein 90.

Lei Wang, Q. You, Dongdong Li, 2016, Journal of medicinal chemistry.

Effective Screening Strategy Using Ensembled Pharmacophore Models Combined with Cascade Docking: Application to p53-MDM2 Interaction Inhibitors

Fang Liu, Xiaoli Xu, Lei Wang, 2013, J. Chem. Inf. Model..

Synthesis and evaluation of a novel class Hsp90 inhibitors containing 1-phenylpiperazine scaffold.

Q. You, Haopeng Sun, Xiaoli Xu, 2014, Bioorganic & medicinal chemistry letters.

Synthesis and antibacterial activity of 5-methylphenanthridium derivatives as FtsZ inhibitors.

S. Semple, H. Venter, Jingru Liu, 2017, Bioorganic & medicinal chemistry letters.

Discovery and Modification of in Vivo Active Nrf2 Activators with 1,2,4-Oxadiazole Core: Hits Identification and Structure-Activity Relationship Study.

Q. You, Meng-Chen Lu, Zhengyu Jiang, 2015, Journal of Medicinal Chemistry.