F. Fruttarolo

发表

Design, synthesis, and biological evaluation of C9- and C2-substituted pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidines as new A2A and A3 adenosine receptors antagonists.

Pier Andrea Borea, K. Varani, S. Merighi, 2003, Journal of medicinal chemistry.

New heterocyclic ligands for the adenosine receptors P1 and for the ATP receptors P2.

P. Borea, P. Baraldi, R. Romagnoli, 2005, Farmaco.

Novel 8-heterocyclyl xanthine derivatives in drug development – an update

P. Baraldi, R. Romagnoli, D. Preti, 2007, Expert opinion on drug discovery.

[3H]-MRE 2029-F20, a selective antagonist radioligand for the human A2B adenosine receptors.

K. Varani, S. Merighi, S. Gessi, 2004, Bioorganic & medicinal chemistry letters.

New strategies for the synthesis of A3 adenosine receptor antagonists.

K. Varani, P. Borea, P. Baraldi, 2003, Bioorganic & medicinal chemistry.

Microwave-assisted synthesis of thieno[2,3-c]pyridine derivatives as a new series of allosteric enhancers at the adenosine A1 receptor

K. Varani, P. Borea, P. Baraldi, 2006 .

Hybrid molecules between distamycin A and active moieties of antitumor agents.

P. Baraldi, R. Romagnoli, D. Preti, 2007, Bioorganic & medicinal chemistry.

Design, synthesis, and biological evaluation of new 8-heterocyclic xanthine derivatives as highly potent and selective human A2B adenosine receptor antagonists.

K. Varani, S. Merighi, S. Gessi, 2004, Journal of medicinal chemistry.

Pharmacophore based receptor modeling: the case of adenosine A3 receptor antagonists. An approach to the optimization of protein models.

M. Botta, T. Tuccinardi, A. Martinelli, 2006, Journal of medicinal chemistry.

Synthesis and biological evaluation of novel 1-deoxy-1-[6-[((hetero)arylcarbonyl)hydrazino]- 9H-purin-9-yl]-N-ethyl-beta-D-ribofuranuronamide derivatives as useful templates for the development of A2B adenosine receptor agonists.

K. Varani, P. Borea, P. Baraldi, 2007, Journal of medicinal chemistry.

Allosteric enhancers for A1 adenosine receptor.

P. Baraldi, R. Romagnoli, D. Preti, 2007, Mini reviews in medicinal chemistry.

Synthesis of a new series of pyrazolo[1,5-a]pyrimidines structurally related to zaleplon

E. Ongini, P. Borea, P. Baraldi, 2007 .

DNA minor groove binders as potential antitumor and antimicrobial agents

P. Baraldi, M. Pavani, R. Romagnoli, 2004, Medicinal research reviews.

Hybrid molecules containing benzo[4,5]imidazo[1,2-d][1,2,4]thiadiazole and alpha-bromoacryloyl moieties as potent apoptosis inducers on human myeloid leukaemia cells.

O. Cruz-López, J. Heilmann, P. Baraldi, 2007, Bioorganic & medicinal chemistry letters.

Synthesis and biological evaluation of 2-amino-3-(3',4',5'-trimethoxybenzoyl)-5-aryl thiophenes as a new class of potent antitubulin agents.

R. Gambari, M. Borgatti, P. Baraldi, 2006, Journal of medicinal chemistry.

Synthesis and biological effects of a new series of 2-amino-3-benzoylthiophenes as allosteric enhancers of A1-adenosine receptor.

I. Lampronti, A. Zaid, J. Shryock, 2000, Bioorganic & medicinal chemistry letters.

Synthesis and biological evaluation of 2- and 3-aminobenzo[b]thiophene derivatives as antimitotic agents and inhibitors of tubulin polymerization.

Jan Balzarini, John A Hadfield, Andrea Brancale, 2007, Journal of medicinal chemistry.

Synthesis of new pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidines and related heterocycles

P. Baraldi, H. El-Kashef, P. Vanelle, 2004 .

New pyrrolo[2,1-f]purine-2,4-dione and imidazo[2,1-f]purine-2,4-dione derivatives as potent and selective human A3 adenosine receptor antagonists.

K. Varani, S. Merighi, P. Borea, 2005, Journal of medicinal chemistry.

Synthesis and biological evaluation of 2-(3',4',5'-trimethoxybenzoyl)-3-amino 5-aryl thiophenes as a new class of tubulin inhibitors.

J. Balzarini, M. Jordan, P. Baraldi, 2006, Journal of medicinal chemistry.

Recent developments in the field of A3 adenosine receptor antagonists

K. Varani, S. Merighi, S. Gessi, 2003 .

Synthesis of a New Series of Pyrazolo[1,5-a]pyrimidines Structurally Related to Zaleplon.

E. Ongini, P. Borea, P. Baraldi, 2007 .

DNA minor groove binders as potential antitumor and antimicrobial agents

P. Baraldi, M. Pavani, R. Romagnoli, 2004, Medicinal research reviews.

Hybrid molecules based on distamycin A as potential antitumor agents

A. Zaid, P. Baraldi, M. Pavani, 2005 .

Recent improvements in the development of A2B adenosine receptor agonists

P. Baraldi, R. Romagnoli, D. Preti, 2009, Purinergic Signalling.

Recent improvements in the development of A2B adenosine receptor agonists

P. Baraldi, R. Romagnoli, D. Preti, 2008, Purinergic Signalling.

Recent developments in the field of A2A and A3 adenosine receptor antagonists.

K. Varani, P. Borea, P. Baraldi, 2003, European journal of medicinal chemistry.

Synthesis and biological evaluation of novel N6-[4-(substituted)sulfonamidophenylcarbamoyl]adenosine-5'-uronamides as A3 adenosine receptor agonists.

K. Varani, P. Borea, P. Baraldi, 2004, Journal of medicinal chemistry.

N6-[(Hetero)aryl/(cyclo)alkyl-carbamoyl-methoxy-phenyl]-(2-chloro)-5′-N-ethylcarboxamido-adenosines: The first example of adenosine-related structures with potent agonist activity at the human A2B adenosine receptor

K. Varani, S. Gessi, P. Borea, 2007 .

N(6)-[(hetero)aryl/(cyclo)alkyl-carbamoyl-methoxy-phenyl]-(2-chloro)-5'-N-ethylcarboxamido-adenosines: the first example of adenosine-related structures with potent agonist activity at the human A(2B) adenosine receptor.

K. Varani, S. Gessi, P. Borea, 2007, Bioorganic & Medicinal Chemistry.

DNA minor-groove binders. Design, synthesis and biological evaluation of ligands structurally related to CC-1065, distamycin, and anthramycin

P. Baraldi, R. Romagnoli, D. Preti, 2003 .

Pyrazolo[4,3-e][1,2,4]Triazolo[1,5-c]Pyrimidine Template: Organic and Medicinal Chemistry Approach

P. Borea, P. Baraldi, R. Romagnoli, 2006 .

Pyrazolo[4,3‐e][1,2,4]triazolo[1,5‐c]pyrimidine Template: Organic and Medicinal Chemistry Approach

P. Borea, P. Baraldi, R. Romagnoli, 2007 .

Pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidine ligands, new tools to characterize A3 adenosine receptors in human tumor cell lines.

K. Varani, S. Merighi, S. Gessi, 2005, Current medicinal chemistry.

New 2-arylpyrazolo[4,3-c]quinoline derivatives as potent and selective human A3 adenosine receptor antagonists.

K. Varani, P. Borea, P. Baraldi, 2005, Journal of medicinal chemistry.

Recent improvements in the field of A3 adenosine receptor ligands

P. Borea, P. Baraldi, R. Romagnoli, 2005 .

Ligands for A2B adenosine receptor subtype.

P. Baraldi, R. Romagnoli, D. Preti, 2006, Current medicinal chemistry.