J. Shibata

发表

TAC-101, a benzoic acid derivative, inhibits liver metastasis of human gastrointestinal cancer and prolongs the life-span

K. Wierzba, Yuji Yamada, K. Murakami, 1998, Clinical & Experimental Metastasis.

A Potential Use of a Synthetic Retinoid TAC‐101 as an Orally Active Agent That Blocks Angiogenesis in Liver Metastases of Human Stomach Cancer Cells

K. Wierzba, Yuji Yamada, K. Murakami, 2001, Japanese journal of cancer research : Gann.

Both N- and C-terminal transactivation functions of DNA-bound ERalpha are blocked by a novel synthetic estrogen ligand.

S. Kato, J. Yanagisawa, O. Wada, 2003, Biochemical and biophysical research communications.

TAS-108, a novel oral steroidal antiestrogenic agent, is a pure antagonist on estrogen receptor alpha and a partial agonist on estrogen receptor beta with low uterotrophic effect.

A. Buzdar, Y. Aoyagi, K. Wierzba, 2005, Clinical cancer research : an official journal of the American Association for Cancer Research.

Inhibition of angiogenesis and intrahepatic growth of colon cancer by TAC-101.

I. Saiki, K. Murakami, Y. Yamada, 1999, Clinical cancer research : an official journal of the American Association for Cancer Research.

TAC‐101 (4‐[3,5‐bis(trimethylsilyl)benzamido]benzoic acid) Inhibits Spontaneous Mediastinal Lymph Node Metastasis Produced by Orthotopic Implantation of Lewis Lung Carcinoma

I. Saiki, Yuji Yamada, K. Murakami, 1999, Japanese journal of cancer research : Gann.

DISTRIBUTION OF (7α)-21-[4-[(DIETHYLAMINO) METHYL]-2-METHOXYPHENOXY]-7-METHYL-19-NORPREGNA-1,3,5(10)-TRIEN-3-OL-20-[14C]2-HYDROXY-1,2,3-PROPANETRICARBOXYLATE ([14C]TAS-108) AND ITS METABOLITES AFTER SINGLE ORAL ADMINISTRATION TO RATS BEARING 7,12-DIMETHYLBENZ(α)ANTHRACENE-INDUCED MAMMARY TUMOR

A. Buzdar, S. Nagayama, H. Yamaya, 2006, Drug Metabolism and Disposition.

2-HYDROXY-1 , 2 , 3-PROPANETRICARBOXYLATE ( [ 14 C ] TAS-108 ) AND ITS METABOLITES AFTER SINGLE ORAL ADMINISTRATION TO RATS BEARING 7 , 12-DIMETHYLBENZ ( ) ANTHRACENE-INDUCED MAMMARY TUMOR

A. Buzdar, Ken‐ichiro Yoshida, S. Nagayama, 2006 .

Comparative pharmacodynamic analysis of TAT-59 and tamoxifen in rats bearing DMBA-induced mammary carcinoma

Y. Sugimoto, E. Matsushima, H. Yamaya, 2004, Cancer Chemotherapy and Pharmacology.

Interaction of DP-TAT-59, an active metabolite of new triphenylethylene-derivative (TAT-59), with estrogen receptors

T. Hirose, K. Wierzba, Yuji Yamada, 1992, The Journal of Steroid Biochemistry and Molecular Biology.

Antitumor activity of a novel podophyllotoxin derivative (TOP-53) against lung cancer and lung metastatic cancer.

T. Tsuruo, Y. Sugimoto, K. Wierzba, 1996, Cancer research.

Oral fluoropyrimidine may augment the efficacy of aromatase inhibitor via the down-regulation of estrogen receptor in estrogen-responsive breast cancer xenografts

F. Nakagawa, S. Noguchi, J. Uchida, 2011, Breast Cancer Research and Treatment.

TAS-108, a Novel Oral Steroidal Antiestrogenic Agent, Is a Pure Antagonist on Estrogen Receptor α and a Partial Agonist on Estrogen Receptor β with Low Uterotrophic Effect

A. Buzdar, Y. Aoyagi, K. Wierzba, 2005 .

Antitumor agents. 3. Synthesis and biological activity of 4 beta-alkyl derivatives containing hydroxy, amino, and amido groups of 4'-O-demethyl-4-desoxypodophyllotoxin as antitumor agents.

Y. Sugimoto, K. Wierzba, T. Terada, 1993, Journal of medicinal chemistry.

Anticancer effect of 4-[3,5-bis(trimethylsilyl)benzamido] benzoic acid (TAC-101) against A549 non-small cell lung cancer cell line is related to its anti-invasive activity.

Y. Aoyagi, K. Wierzba, K. Murakami, 2000, Anticancer research.

Antiestrogenic activity of DP-TAT-59, an active metabolite of TAT-59 against human breast cancer

Yuji Yamada, M. Nukatsuka, J. Shibata, 1997, Cancer Chemotherapy and Pharmacology.

[Studies on fibrinolysis and ascites accumulation associated with peritonitis carcinomatosa--inducer of plasminogen activator (IPA) in malignant ascites tumor].

J. Shibata, 1986, Nihon Sanka Fujinka Gakkai zasshi.

Life prolonging effect of antitumor agents on postoperative adjuvant therapy in the lung spontaneous metastasis model in mice.

M. Fukushima, K. Murakami, T. Utsugi, 1998, Anticancer research.

Synthesis and antiestrogenic activity of the compounds related to the metabolites of (E)-4-[1-[4-[2-(dimethylamino)ethoxy]phenyl]- 2-(4-isopropylphenyl)-1-butenyl]phenyl monophosphate (TAT-59) [corrected].

T. Asao, J. Shibata, T. Toko, 1991, Chemical & pharmaceutical bulletin.

Detection and quantitation of thymidylate synthase mRNA in human colon adenocarcinoma cell line resistant to 5-fluorouracil by competitive PCR.

H. Shibata, K. Aiba, N. Horikoshi, 1998, Anticancer research.

Estrogen agonistic/antagonistic effects of miproxifene phosphate (TAT-59)

A. Fujioka, H. Saito, K. Wierzba, 2000, Cancer Chemotherapy and Pharmacology.