J. Singhal

发表

RLIP76 Inhibition: A Promising Developmental Therapy for Neuroblastoma

S. Awasthi, S. Singhal, P. Singhal, 2017, Pharmaceutical Research.

Decay-Accelerating Factor and Cytoskeleton Redistribution Pattern in HeLa Cells Infected with RecombinantEscherichia coli Strains Expressing Dr Family of Adhesins

R. Selvarangan, V. Popov, P. Goluszko, 1999, Infection and Immunity.

Oxidative stress and dietary phytochemicals: Role in cancer chemoprevention and treatment.

S. Awasthi, S. Singhal, Shireen Chikara, 2018, Cancer letters.

Prevention of mammary carcinogenesis in MMTV‐neu mice by targeting RLIP

Prakash Kulkarni, R. Salgia, S. Awasthi, 2021, Molecular carcinogenesis.

The determination of glutathione-4-hydroxynonenal (GSHNE), E-4-hydroxynonenal (HNE), and E-1-hydroxynon-2-en-4-one (HNO) in mouse liver tissue by LC-ESI-MS

D. Armstrong, S. Awasthi, Eranda Wanigasekara, 2008, Analytical and bioanalytical chemistry.

Metastasis of breast tumor cells to brain is suppressed by targeting RLIP alone and in combination with 2'-Hydroxyflavanone.

R. Salgia, S. Awasthi, S. Singhal, 2018, Cancer letters.

2′‐Hydroxyflavanone inhibits in vitro and in vivo growth of breast cancer cells by targeting RLIP76

R. Salgia, S. Awasthi, S. Singhal, 2018, Molecular carcinogenesis.

LR-90 prevents methylglyoxal-induced oxidative stress and apoptosis in human endothelial cells

S. Awasthi, S. Rahbar, S. Singhal, 2014, Apoptosis.

1,3-Bis(3,5-dichlorophenyl) urea compound 'COH-SR4' inhibits proliferation and activates apoptosis in melanoma.

R. Jove, S. Awasthi, S. Rahbar, 2012, Biochemical pharmacology.

RLIP76, a Glutathione-Conjugate Transporter, Plays a Major Role in the Pathogenesis of Metabolic Syndrome

R. Vatsyayan, S. Awasthi, S. Singhal, 2011, PloS one.

RLIP76: a target for kidney cancer therapy.

Y. Awasthi, M. Sahu, S. Awasthi, 2009, Cancer research.

Antioxidant role of glutathione S-transferases: 4-Hydroxynonenal, a key molecule in stress-mediated signaling.

S. Awasthi, Sharda P. Singh, S. Singhal, 2015, Toxicology and applied pharmacology.

Glutathione-Conjugate Transport by RLIP76 Is Required for Clathrin-Dependent Endocytosis and Chemical Carcinogenesis

Sumihiro Suzuki, R. Vatsyayan, Y. Awasthi, 2011, Molecular Cancer Therapeutics.

Purification and characterization of glutathione S-transferases of rat uterus.

C. Yallampalli, S. Awasthi, S. Singhal, 1996, The international journal of biochemistry & cell biology.

Targeting p 53-Null Neuroblastomas through RLIP 76

R. Vatsyayan, S. Awasthi, S. Singhal, 2011 .

Targeting p53-Null Neuroblastomas through RLIP76

R. Vatsyayan, S. Awasthi, S. Singhal, 2011, Cancer Prevention Research.

A Central Role of RLIP76 in Regulation of Glycemic Control

R. Vatsyayan, Y. Awasthi, S. Awasthi, 2009, Diabetes.

Synergistic efficacy of RLIP inhibition and 2′‐hydroxyflavanone against DMBA‐induced mammary carcinogenesis in SENCAR mice

R. Salgia, S. Awasthi, S. Vonderfecht, 2019, Molecular carcinogenesis.

RLIP76 transports vinorelbine and mediates drug resistance in non-small cell lung cancer.

D. Stuckler, Y. Awasthi, S. Awasthi, 2005, Cancer research.

RLIP 76 Transports Vinorelbine and Mediates Drug Resistance in Non – Small Cell Lung Cancer

D. Stuckler, Y. Awasthi, S. Awasthi, 2005 .

Effects of mGST A4 transfection on 4-hydroxynonenal-mediated apoptosis and differentiation of K562 human erythroleukemia cells.

F. V. van Kuijk, Y. Awasthi, S. Awasthi, 1999, Archives of biochemistry and biophysics.

Interaction of Dr Adhesin with Collagen Type IV Is a Critical Step in Escherichia coli Renal Persistence

R. Selvarangan, S. Moseley, B. Nowicki, 2004, Infection and Immunity.

Inverse Relationship between Severity of Experimental Pyelonephritis and Nitric Oxide Production in C3H/HeJ Mice

C. Yallampalli, S. Nowicki, L. Fang, 1999, Infection and Immunity.

Inverse Relationship between Severity of Experimental Pyelonephritis and Nitric Oxide Production in C 3 H / HeJ Mice

C. Yallampalli, B. Nowicki, S. Nowicki, 1999 .

Determinants of differential doxorubicin sensitivity between SCLC and NSCLC

Y. Awasthi, S. Awasthi, S. Singhal, 2006, FEBS letters.

Didymin Induces Apoptosis by Inhibiting N-Myc and Upregulating RKIP in Neuroblastoma

Ashutosh, R. Vatsyayan, S. Awasthi, 2011, Cancer Prevention Research.

RLIP76 Knockdown Attenuates Obesity Due to High-Fat Diet*

R. Natarajan, S. Awasthi, S. Singhal, 2013 .

Diminished drug transport and augmented radiation sensitivity caused by loss of RLIP76

M. Sahu, S. Awasthi, S. Singhal, 2008, FEBS letters.

RLIP76: A novel glutathione-conjugate and multi-drug transporter.

S. Singhal, Sushma Yadav, J. Singhal, 2009, Biochemical pharmacology.

Hsf-1 and POB1 Induce Drug Sensitivity and Apoptosis by Inhibiting Ralbp1*

S. Awasthi, S. Singhal, Sushma Yadav, 2008, Journal of Biological Chemistry.

Lethal Outcome of Uterine Infection in Pregnant but Not in Nonpregnant Rats and Increased Death Rate With Inhibition of Nitric Oxide

C. Yallampalli, B. Nowicki, S. Nowicki, 1997, American journal of reproductive immunology.

A Central Role of RLIP 76 in Regulation of Glycemic Control Running Title : Mechanisms of Insulin Resistance

R. Vatsyayan, Y. Awasthi, S. Awasthi, 2009 .

Role of Decay-Accelerating Factor Domains and Anchorage in Internalization of Dr-Fimbriated Escherichia coli

R. Selvarangan, B. Nowicki, D. Lublin, 2000, Infection and Immunity.

Elimination of human folypolyglutamate synthetase alters programming and plasticity of somatic cells

A. Riggs, T. O'Connor, Juan Du, 2019, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Rlip Depletion Suppresses Growth of Breast Cancer

S. Rehman, Jihyun Lee, S. Awasthi, 2020, Cancers.

Targeting RLIP with CRISPR/Cas9 controls tumor growth.

R. Salgia, S. Awasthi, S. Singhal, 2020, Carcinogenesis.

SOX9: The Master Regulator of Cell Fate in Breast Cancer.

R. Salgia, S. Awasthi, S. Singhal, 2020, Biochemical pharmacology.

Didymin: an orally active citrus flavonoid for targeting neuroblastoma

David Horne, Sanjay Awasthi, S. Awasthi, 2017, Oncotarget.

Notch Signaling in Breast Cancer: From Pathway Analysis to Therapy.

R. Salgia, S. Awasthi, S. Singhal, 2019, Cancer letters.

2’-Hydroxyflavanone effectively targets RLIP76-mediated drug transport and regulates critical signaling networks in breast cancer

R. Salgia, S. Awasthi, Hongzhi Li, 2018, Oncotarget.

Targeting the mercapturic acid pathway and vicenin-2 for prevention of prostate cancer.

S. Awasthi, D. Jain, S. Singhal, 2017, Biochimica et biophysica acta. Reviews on cancer.

Anti-cancer effects of novel flavonoid vicenin-2 as a single agent and in synergistic combination with docetaxel in prostate cancer.

R. Roby, R. Vatsyayan, S. Awasthi, 2011, Biochemical pharmacology.

RALBP1/RLIP76 mediates multidrug resistance.

S. Awasthi, S. Singhal, Sushma Yadav, 2007, International journal of oncology.

Ral-Binding Protein is Required for the Maturation and Function of Dendritic Cells

Y. Awasthi, M. Sahu, S. Awasthi, 2010 .

Translational opportunities for broad‐spectrum natural phytochemicals and targeted agent combinations in breast cancer

S. Awasthi, S. Singhal, Shireen Chikara, 2018, International journal of cancer.

Therapeutic targeting of miRNA-216b in cancer.

R. Salgia, S. Awasthi, S. Singhal, 2020, Cancer letters.

Bioenergetic modulation with the mitochondria uncouplers SR4 and niclosamide prevents proliferation and growth of treatment-naïve and vemurafenib-resistant melanomas

A. Riggs, J. Kusari, S. Singhal, 2018, Oncotarget.

Rlip depletion prevents spontaneous neoplasia in TP53 null mice

Zheng Liu, Meenakshi Awasthi, Sanjay Awasthi, 2018, Proceedings of the National Academy of Sciences.

Novel compound 1,3-bis (3,5-dichlorophenyl) urea inhibits lung cancer progression.

S. Awasthi, S. Rahbar, S. Singhal, 2013, Biochemical pharmacology.

2'-Hydroxyflavanone: A promising molecule for kidney cancer prevention.

A. Riggs, S. Awasthi, S. Singhal, 2015, Biochemical pharmacology.

RLIP76 Targeted Therapy for Kidney Cancer

S. Awasthi, S. Singhal, J. Figarola, 2015, Pharmaceutical Research.

Regression of prostate cancer xenografts by RLIP76 depletion.

S. Awasthi, S. Singhal, Kathryn L. Leake, 2009, Biochemical pharmacology.

Nutlin‐3 enhances sorafenib efficacy in renal cell carcinoma

R. Vatsyayan, S. Awasthi, S. Singhal, 2013, Molecular carcinogenesis.

Apoptosis and Differentiation of K562 Cells by Targeting GST-O1 to Inhibit 4-HNE Metabolism

S. Awasthi, S. Singhal, Kathryn L. Leake, 2014 .

2'-hydroxyflavanone inhibits proliferation, tumor vascularization and promotes normal differentiation in VHL-mutant renal cell carcinoma.

R. Vatsyayan, L. Prokai, S. Awasthi, 2011, Carcinogenesis.

RLIP76 in defense of radiation poisoning.

Sumihiro Suzuki, D. Armstrong, P. Dent, 2008, International journal of radiation oncology, biology, physics.

RLIP76 is a major determinant of radiation sensitivity.

P. Dent, A. Yacoub, P. Boor, 2005, Cancer research.

RLIP76 Regulates PI3K/Akt Signaling and Chemo-Radiotherapy Resistance in Pancreatic Cancer

S. Awasthi, S. Singhal, Kathryn L. Leake, 2012, PloS one.

Doxorubicin transport by RALBP 1 and ABCG 2 in lung and breast cancer

Y. Awasthi, S. Awasthi, A. Lacko, 2022 .

Activating p53 function by targeting RLIP.

R. Salgia, S. Awasthi, S. Singhal, 2021, Biochimica et biophysica acta. Reviews on cancer.

2'-Hydroxyflavanone: A novel strategy for targeting breast cancer

S. Awasthi, S. Singhal, Shireen Chikara, 2017, Oncotarget.

Regression of lung and colon cancer xenografts by depleting or inhibiting RLIP76 (Ral-binding protein 1).

P. Boor, Y. Awasthi, S. Awasthi, 2007, Cancer research.

hSET1: a novel approach for colon cancer therapy.

S. Awasthi, S. Singhal, Sushma Yadav, 2009, Biochemical pharmacology.

LR-90 prevents methylglyoxal-induced oxidative stress and apoptosis in human endothelial cells

S. Awasthi, S. Rahbar, S. Singhal, 2014, Apoptosis.

2'-Hydroxyflavanone induced changes in the proteomic profile of breast cancer cells.

R. Salgia, S. Awasthi, S. Singhal, 2019, Journal of proteomics.

Depletion of RLIP76 sensitizes lung cancer cells to doxorubicin.

Y. Awasthi, S. Awasthi, S. Singhal, 2005, Biochemical pharmacology.

Anticancer activity of 2’-hydroxyflavanone towards lung cancer

Yate-Ching Yuan, V. Tonk, Y. Awasthi, 2018, Oncotarget.

Mitogenic and drug-resistance mediating effects of PKCα require RLIP76

Y. Awasthi, S. Awasthi, S. Singhal, 2006 .

The role of PKCα and RLIP76 in transport‐mediated doxorubicin‐resistance in lung cancer

Y. Awasthi, S. Awasthi, S. Singhal, 2005, FEBS letters.

POB1 over-expression inhibits RLIP76-mediated transport of glutathione-conjugates, drugs and promotes apoptosis.

Y. Awasthi, S. Awasthi, S. Singhal, 2005, Biochemical and biophysical research communications.

Is a Major Determinant of Radiation Sensitivity

P. Dent, A. Yacoub, P. Boor, 2005 .

Purification and functional reconstitution of intact ral-binding Gtpase activating protein, RLIP76, in artificial liposomes.

Y. Awasthi, S. Awasthi, R. Sharma, 2001, Acta biochimica Polonica.

Proteomic Analysis of Signaling Network Regulation in Renal Cell Carcinomas with Differential Hypoxia-Inducible Factor-2α Expression

R. Vatsyayan, Jia Guo, L. Prokai, 2013, PloS one.

SR4 Uncouples Mitochondrial Oxidative Phosphorylation, Modulates AMP-dependent Kinase (AMPK)-Mammalian Target of Rapamycin (mTOR) Signaling, and Inhibits Proliferation of HepG2 Hepatocarcinoma Cells*

A. Riggs, S. Awasthi, G. Rogers, 2015, The Journal of Biological Chemistry.

Role of RLIP76 in lung cancer doxorubicin resistance: I. The ATPase activity of RLIP76 correlates with doxorubicin and 4-hydroxynonenal resistance in lung cancer cells.

Shivendra V. Singh, Y. Awasthi, Rajendra K. Sharma, 2003, International journal of oncology.

RLIP76 Inhibition: A Promising Developmental Therapy for Neuroblastoma

S. Awasthi, S. Singhal, P. Singhal, 2017, Pharmaceutical Research.

Increased expression of cdc2 inhibits transport function of RLIP76 and promotes apoptosis.

R. Vatsyayan, P. Chaudhary, S. Awasthi, 2009, Cancer letters.

Doxorubicin transport by RALBP1 and ABCG2 in lung and breast cancer.

Y. Awasthi, S. Awasthi, A. Lacko, 2007, International journal of oncology.

RLIP76 Protein Knockdown Attenuates Obesity Due to a High-fat Diet*

R. Natarajan, S. Awasthi, S. Singhal, 2013, The Journal of Biological Chemistry.

RLIP76 Targeted Therapy for Kidney Cancer

S. Awasthi, S. Singhal, J. Figarola, 2015, Pharmaceutical Research.

Identification of membrane-anchoring domains of RLIP76 using deletion mutant analyses.

T. Albrecht, Y. Awasthi, S. Awasthi, 2004, Biochemistry.

Role of RLIP76 in lung cancer doxorubicin resistance: III. Anti-RLIP76 antibodies trigger apoptosis in lung cancer cells and synergistically increase doxorubicin cytotoxicity.

Y. Awasthi, S. Awasthi, P. Zimniak, 2003, International journal of oncology.

Role of RLIP76 in lung cancer doxorubicin resistance: II. Doxorubicin transport in lung cancer by RLIP76.