P. Jakobs

Ca2+ coordination controls sonic hedgehog structure and its Scube2-regulated release

D. Hoffmann, D. Seidler, K. Grobe, 2017, Journal of Cell Science.

Conserved cholesterol-related activities of Dispatched 1 drive Sonic hedgehog shedding from the cell membrane

U. Rescher, K. Grobe, U. Kirchhefer, 2021, Journal of cell science.

Conserved cholesterol-related activities of Dispatched drive Sonic hedgehog shedding from the cell membrane

U. Rescher, K. Grobe, D. Manikowski, 2020, bioRxiv.

Hedgehog lipids: Promotors of alternative morphogen release and signaling?

K. Grobe, D. Manikowski, P. Jakobs, 2021, BioEssays : news and reviews in molecular, cellular and developmental biology.

Hedgehog lipids: Promotors of alternativemorphogen release and signaling? Conflicting findings on lipidated Hedgehog transport and signaling can be explained by alternative regulatedmechanisms to release themorphogen

K. Grobe, P. Jakobs, K. Ehring, 2021 .

Scube 2 enhances proteolytic Shh processing from the surface of producing cells 1 2

Ute Pickhinke, K. Grobe, S. Exner, 2014 .

Soluble Heparin and Heparan Sulfate Glycosaminoglycans Interfere with Sonic Hedgehog Solubilization and Receptor Binding

K. Grobe, D. Manikowski, P. Jakobs, 2019, Molecules.

Scube2 enhances proteolytic Shh processing from the surface of Shh-producing cells

D. Seidler, Ute Pickhinke, K. Grobe, 2014, Journal of Cell Science.

C-Terminal Peptide Modifications Reveal Direct and Indirect Roles of Hedgehog Morphogen Cholesteroylation

Georg Steffes, K. Grobe, D. Manikowski, 2021, Frontiers in Cell and Developmental Biology.

Bridging the gap: heparan sulfate and Scube2 assemble Sonic hedgehog release complexes at the surface of producing cells

D. Seidler, R. Dreier, K. Grobe, 2016, Scientific Reports.