H. Kadowaki

发表

Role of Apoptosis Signal-regulating Kinase 1 (ASK1) as an Activator of the GAPDH-Siah1 Stress-Signaling Cascade*

Carlos A. Tristan, A. Sawa, H. Ichijo, 2014, The Journal of Biological Chemistry.

Pre-emptive Quality Control Protects the ER from Protein Overload via the Proximity of ERAD Components and SRP.

Takashi Sato, H. Kai, T. Natsume, 2015, Cell reports.

Amyloid β induces neuronal cell death through ROS-mediated ASK1 activation

F. Urano, H. Masutani, J. Yodoi, 2005, Cell Death and Differentiation.

ER Quality Control and ER Stress-induced Cell Death in Neurodegenerative Diseases

H. Nishitoh, H. Kadowaki, Atsushi Nagai, 2007 .

Survival and apoptosis signals in ER stress: the role of protein kinases

H. Ichijo, H. Nishitoh, H. Kadowaki, 2004, Journal of Chemical Neuroanatomy.

The Cytoplasmic Domain of Alzheimer's Amyloid-β Protein Precursor Causes Sustained Apoptosis Signal-Regulating Kinase 1/c-Jun NH2-Terminal Kinase-Mediated Neurotoxic Signal via Dimerization

I. Nishimoto, H. Ichijo, H. Nishitoh, 2003, Journal of Pharmacology and Experimental Therapeutics.

ER-resident sensor PERK is essential for mitochondrial thermogenesis in brown adipose tissue

Katsuaki Sato, S. Torii, H. Ichijo, 2020, Life Science Alliance.

A systematic immunoprecipitation approach reinforces the concept of common conformational alterations in amyotrophic lateral sclerosis-linked SOD1 mutants

S. Tsuji, H. Ichijo, H. Nishitoh, 2015, Neurobiology of Disease.

A novel monoclonal antibody reveals a conformational alteration shared by amyotrophic lateral sclerosis‐linked SOD1 mutants

S. Tsuji, H. Ichijo, H. Nishitoh, 2012, Annals of neurology.

Endoplasmic reticulum quality control by garbage disposal

H. Nishitoh, H. Kadowaki, 2018, The FEBS journal.

Involvement of ASK1-p38 pathway in the pathogenesis of diabetes triggered by pancreatic ß cell exhaustion.

Y. Ouchi, H. Ichijo, K. Takeda, 2013, Biochimica et biophysica acta.

USP14 inhibits ER-associated degradation via interaction with IRE1alpha.

H. Ichijo, K. Takeda, H. Nishitoh, 2009, Biochemical and biophysical research communications.

The cytoplasmic domain of Alzheimer’s amyloid- protein precursor causes sustained ASK1/JNK mediated neurotoxic signal via dimerization

I. Nishimoto, H. Ichijo, H. Nishitoh, 2003 .

Chemical chaperones ameliorate neurodegenerative disorders in Derlin-1-deficient mice via improvement of cholesterol biosynthesis

H. Nishitoh, H. Kadowaki, Takashi Sugiyama, 2022, Scientific reports.

Molecular mechanism of ER stress-induced pre-emptive quality control involving association of the translocon, Derlin-1, and HRD1

H. Nishitoh, Y. Takami, H. Kadowaki, 2018, Scientific Reports.

CHIP‐dependent termination of MEKK2 regulates temporal ERK activation required for proper hyperosmotic response

H. Shibuya, Keiji Tanaka, H. Ichijo, 2010, The EMBO journal.

SOD1 as a molecular switch for initiating the homeostatic ER stress response under zinc deficiency.

H. Ichijo, K. Takeda, H. Nishitoh, 2013, Molecular cell.

Amyloid beta induces neuronal cell death through ROS-mediated ASK1 activation.

F. Urano, H. Masutani, J. Yodoi, 2005, Cell death and differentiation.

Signaling Pathways from the Endoplasmic Reticulum and Their Roles in Disease

H. Nishitoh, Hisae Kadowaki, Hideki Nishitoh, 2013, Genes.

Als-linked Mutant Sod1 Induces Er Stress-and Ask1-dependent Motor Neuron Death by Targeting Derlin-1 -induced Cell Death Remains Controversial. Here We Show That Sod1 Mut Specifically Interacted with Derlin-1, a Component of Endoplasmic Reticulum (er)-associated Degradation (erad) Machinery and Trig

Takanori Yokota, H. Ichijo, K. Takeda, 2022 .

Molecular mechanism of ER stress-induced pre-emptive quality control involving association of the translocon, Derlin-1, and HRD1

H. Nishitoh, Y. Takami, H. Kadowaki, 2018, Scientific Reports.

Homeostatic Regulation of Seizure Susceptibility and Cognitive Function by ER Quality Controller Derlin-1 through Maintenance of Adult Neurogenesis

T. Katagiri, H. Nishitoh, K. Tanimoto, 2023, bioRxiv.

ERAD components Derlin-1 and Derlin-2 are essential for postnatal brain development and motor function

K. Mikoshiba, A. Futatsugi, T. Katagiri, 2021, iScience.

Homeostatic Regulation of Seizure Susceptibility and Cognitive Function by Derlin-1 through Maintenance of Adult Neurogenesis

T. Katagiri, H. Nishitoh, K. Tanimoto, 2023, bioRxiv.

A subtype of diabetes mellitus associated with a mutation in the mitochondrial gene

Y. Yazaki, T. Kadowaki, Y. Akanuma, 1995, Muscle & nerve. Supplement.

ALS-linked mutant SOD1 induces ER stress- and ASK1-dependent motor neuron death by targeting Derlin-1.

H. Ichijo, K. Takeda, H. Nishitoh, 2008, Genes & development.

The Derlin-1-Stat5b axis maintains homeostasis of adult hippocampal neurogenesis

H. Kadowaki, Taito Matsuda, Naoya Murao, 2024, EMBO reports.