Yongxue Huang

发表

Design, Synthesis, and Biological Evaluation of Pyrazoline‐Based Hydroxamic Acid Derivatives as Aminopeptidase N (APN) Inhibitors

B. Wang, Wenfang Xu, Yingjie Zhang, 2018, ChemMedChem.

Discovery of a novel chimeric ubenimex-gemcitabine with potent oral antitumor activity.

Jingde Wu, Xuejian Wang, Jian Zhang, 2016, Bioorganic & medicinal chemistry.

Discovery of BC-01, a novel mutual prodrug (hybrid drug) of ubenimex and fluorouracil as anticancer agent.

Xuejian Wang, Yuping Jia, Jian Zhang, 2016, European journal of medicinal chemistry.

Enhanced anticancer activity of 5-FU in combination with Bestatin: Evidence in human tumor-derived cell lines and an H22 tumor-bearing mouse.

Xuejian Wang, Wenfang Xu, Yingjie Zhang, 2015, Drug discoveries & therapeutics.

LJNK, an indoline-2,3-dione-based aminopeptidase N inhibitor with promising antitumor potency

Xuejian Wang, Wenfang Xu, Yingjie Zhang, 2016, Anti-cancer drugs.

Synthesis and biological characterization of ubenimex-fluorouracil conjugates for anti-cancer therapy.

Xuejian Wang, Yuping Jia, Jian Zhang, 2018, European journal of medicinal chemistry.

Novel leucine ureido derivatives as aminopeptidase N inhibitors. Design, synthesis and activity evaluation.

Ping Wu, Yingxia Li, Wenfang Xu, 2016, European journal of medicinal chemistry.

Design, synthesis and preliminary biological evaluation of 4-aminopyrazole derivatives as novel and potent JAKs inhibitors.

B. Wang, Wenfang Xu, Yingjie Zhang, 2016, Bioorganic & medicinal chemistry.

Synthesis and testing of chromogenic phenoxazinone substrates for beta-alanyl aminopeptidase.

Rosaleen J. Anderson, P. Groundwater, J. Perry, 2008, Organic and biomolecular chemistry.

CD13 Inhibition Enhances Cytotoxic Effect of Chemotherapy Agents

Lihong Shi, S. Liang, Weiguo Song, 2018, Front. Pharmacol..

Selective HDAC inhibitors with potent oral activity against leukemia and colorectal cancer: Design, structure-activity relationship and anti-tumor activity study.

Jingde Wu, Wenfang Xu, Yingjie Zhang, 2017, European journal of medicinal chemistry.

Discovery of Novel Pazopanib-Based HDAC and VEGFR Dual Inhibitors Targeting Cancer Epigenetics and Angiogenesis Simultaneously.

Yuping Jia, Wenfang Xu, Yingjie Zhang, 2018, Journal of medicinal chemistry.

Design, synthesis, and antitumor evaluation of histone deacetylase inhibitors with l-phenylglycine scaffold

Wenfang Xu, Yingjie Zhang, Xiaoguang Li, 2015, Drug Design, Development and Therapy.

Synthesis and biological evaluation of novel benzofuroxan-based pyrrolidine hydroxamates as matrix metalloproteinase inhibitors with nitric oxide releasing activity.

Xuejian Wang, Jian Zhang, Wenfang Xu, 2018, Bioorganic & medicinal chemistry.