D. Brown

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Crystal structure of a berenil-d(CGCAAATTTGCG) complex. An example of drug-DNA recognition based on sequence-dependent structural features.

E. Garman, S. Neidle, M. Sanderson, 1992, Journal of molecular biology.

Spectrophotometric assay of POE nonionic surfactants and its application to surfactant sorption isotherms.

P. Jaffé, D. Brown, 2001, Environmental science & technology.

Formation of large molecular weight fragments of DNA is a key committed step of apoptosis in thymocytes.

X. M. Sun, G. Cohen, D. Dinsdale, 1994, Journal of immunology.

Dexamethasone-induced apoptosis involves cleavage of DNA to large fragments prior to internucleosomal fragmentation.

X. M. Sun, G. Cohen, David G. Brown, 1993, The Journal of biological chemistry.

STRUCTURAL ALTERATION IN ISOLATED RAT LIVER NUCLEI AFTER REMOVAL OF TEMPLATE RESTRICTION BY POLYANIONS

D. S. Coffey, E. Arnold, D. Yawn, 1972, The Journal of cell biology.

Friends in Low Places: Intestinal Commensals Limit Colitis through Molecular Mimicry

J. Round, D. Brown, 2017, Cell.

Kinetics of iron-catalyzed decomposition of hydrogen peroxide in alkaline solution

J. Abbot, D. Brown, 1990 .

Effects of chrysotile asbestos on mononuclear cells in vitro.

S. Kagamimori, R. E. Edwards, M. Scott, 1980, British journal of experimental pathology.

Effects of polyamines and methylglyoxal bis(guanylhydrazone) on hepatic nuclear structure and deoxyribonucleic acid template activity.

K. B. Brown, D. Brown, N. Nelson, 1975, The Biochemical journal.

Crystallography in the study of protein-DNA interactions.

P. Freemont, D. Brown, 1996, Methods in molecular biology.

Caspase activation involves the formation of the aposome, a large (approximately 700 kDa) caspase-activating complex.

G. Cohen, K. Cain, C. Langlais, 1999, The Journal of biological chemistry.

The proteins in membrane and cytoplasmic ribosomes of Streptococcus fecalis. An extra protein in the 50-S subparticles of cytoplasmic ribosomes.

A. Abrams, D. Brown, 1970, Biochimica et biophysica acta.

Effects of polyamines and methylglyoxal bis(guanylhydrazone) on Escherichia coli ribonucleic acid polymerase and the template activity of hepatic cell nuclei in vitro.

K. B. Brown, G. Stewart, D. Brown, 1978, Biochimica et biophysica acta.

The release of chromatin template restrictions by natural polyribonucleotides.

D. S. Coffey, D. Brown, 1971, Biochemical and biophysical research communications.

Sequence-dependent effects in drug-DNA interaction: the crystal structure of Hoechst 33258 bound to the d(CGCAAATTTGCG)2 duplex.

S. Neidle, N. Spink, J. V. Skelly, 1994, Nucleic acids research.

Size requirement of polyinosinic acid for DNA synthesis, viral resistance, and increased survival of leukaemic mice.

D. S. Coffey, S. J. Mohr, D. Brown, 1972, Nature: New biology.

Unsymmetrically disubstituted ferrocenes II. The addition of o- and p-quinones to [(dimethylamino)methyl] ferrocene through lithiation

R. Moore, D. Brown, B. W. Rocket, 1967 .

Effects of nonionic surfactants on the UV/visible absorption of bacterial cells.

P. Jaffé, D. Brown, 2001, Biotechnology and bioengineering.

Crystal structures of the thymidine kinase from herpes simplex virus type-I in complex with deoxythymidine and Ganciclovir

W. Summers, P. Rizkallah, R. Visse, 1995, Nature Structural Biology.

Effects of polyinosinic acid and polycytidylic acid on the deoxyribonucleic acid template activity of isolated nuclei and soluble chromatin from rat liver.

D. S. Coffey, D. Brown, 1972, The Journal of biological chemistry.

Crystal structure of a disulfide-linked "trefoil" motif found in a large family of putative growth factors.

P. Freemont, A. De, M. Gorman, 1994, Proceedings of the National Academy of Sciences of the United States of America.

Expansion of Bacteriophages Is Linked to Aggravated Intestinal Inflammation and Colitis.

Ryan M. O’Connell, N. Ajami, J. Round, 2019, Cell host & microbe.

Molecular patterns from a human gut-derived Lactobacillus strain suppress pathogenic infiltration of leukocytes into the central nervous system

D. J. Doty, J. Round, J. Libbey, 2020, Journal of neuroinflammation.

The microbiota protects from viral-induced neurologic damage through microglia-intrinsic TLR signaling

Ryan M. O’Connell, J. Round, R. Fujinami, 2019, eLife.

Apaf-1 oligomerizes into biologically active approximately 700-kDa and inactive approximately 1.4-MDa apoptosome complexes.

G M Cohen, C Langlais, K Cain, 2000, The Journal of biological chemistry.

Direct sulfide oxidation in the solubilization of sulfide ores by Thiobacillus ferrooxidans

D. Brown, J. V. Beck, 1968, Journal of bacteriology.

Effects of nonionic surfactants on bacterial transport through porous media.

P. Jaffé, D G Brown, P R Jaffé, 2001, Environmental science & technology.

Crystal and solution structures of the oligonucleotide d(ATGCGCAT)2: a combined X-ray and NMR study.

R. L. Jones, G. Zon, E. Garman, 1990, Nucleic acids research.

4.29 – Enzymes: Insights for Drug Design from Structure

A. Pannifer, M. Flocco, D. Brown, 2007 .

Effects of Metal Ions and Stabilisers on Peroxide Decomposition During Bleaching

J. Abbot, D. Brown, 1995 .

Magnesium as a stabilizer for peroxide bleaching of mechanical pulp

J. Abbot, D. Brown, 1994 .

The separation of the ribosomal proteins of Streptococcus fecalis by isoelectric focusing. Amino acid composition of the total ribosomal proteins and of an acidic fraction.

C. Baron, A. Abrams, D. Brown, 1968, Biochimica et biophysica acta.

Molecular structure of the B-DNA dodecamer d(CGCAAATTTGCG)2. An examination of propeller twist and minor-groove water structure at 2.2 A resolution.

S Neidle, S. Neidle, K. J. Edwards, 1992, Journal of molecular biology.

NMR and molecular modeling studies of the interaction of berenil and pentamidine with d(CGCAAATTTGCG)2.

S Neidle, A. Lane, S. Neidle, 1993, European journal of biochemistry.

The interaction between vitamin B-12 and micelles in aqueous solution.

D. Brown, L. S. Beckmann, 1976, Biochimica et biophysica acta.

Drug-DNA Recognition: Sequence-Specificity of the DNA Minor Groove Binder Berenil

S. Neidle, C. Laughton, T. C. Jenkins, 1990 .

Transforming growth factor-beta(1) induces apoptosis in rat FaO hepatoma cells via cytochrome c release and oligomerization of Apaf-1 to form a approximately 700-kd apoptosome caspase-processing complex.

K. Cain, R. Roberts, D. Brown, 2000, Hepatology.