C. Kwok

发表

Mosaic Epigenetic Inheritance as a Cause of Early-Onset Colorectal Cancer.

M. A. Sloane, L. Hesson, R. Ward, 2015, JAMA oncology.

De novo constitutional MLH1 epimutations confer early‐onset colorectal cancer in two new sporadic Lynch syndrome cases, with derivation of the epimutation on the paternal allele in one

C. Boland, L. Lipton, R. Ward, 2011, International journal of cancer.

Detection of allelic imbalance in MLH1 expression by pyrosequencing serves as a tool for the identification of germline defects in Lynch syndrome

R. Ward, N. Hawkins, M. Hitchins, 2010, Familial Cancer.

Epigenetic changes associated with disease progression in a mouse model of childhood allergic asthma

Rakesh K. Kumar, P. Foster, J. Mattes, 2013, Disease Models & Mechanisms.

Epigenetic changes associated with disease progression in a model of childhood allergic asthma

Rakesh K. Kumar, P. Foster, J. Mattes, 2013 .

Macrophage development and activation involve coordinated intron retention in key inflammatory regulators

U. Schmitz, J. Rasko, S. Clark, 2020, Nucleic acids research.

Lynch Syndrome Associated with Two MLH1 Promoter Variants and Allelic Imbalance of MLH1 Expression

M. A. Sloane, L. Hesson, J. W. Wong, 2015, Human mutation.

Dominantly inherited constitutional epigenetic silencing of MLH1 in a cancer-affected family is linked to a single nucleotide variant within the 5'UTR.

R. Ward, J. Goldblatt, L. Khachigian, 2011, Cancer cell.

Genetic alterations of m6A regulators predict poorer survival in acute myeloid leukemia

John E. J. Rasko, J. Rasko, J. Wong, 2017, Journal of Hematology & Oncology.

MGMT methylation is associated primarily with the germline C>T SNP (rs16906252) in colorectal cancer and normal colonic mucosa

R. Ward, N. Hawkins, J. Wong, 2009, Modern Pathology.

The MLH1 c.-27C>A and c.85G>T variants are linked to dominantly inherited MLH1 epimutation and are borne on a European ancestral haplotype

U. Ladabaum, R. Ward, M. Ligtenberg, 2013, European Journal of Human Genetics.

Intron retention is regulated by altered MeCP2-mediated splicing factor recruitment

W. Ritchie, J. Rasko, T. Nguyen, 2017, Nature Communications.

Allele Quantification Pyrosequencing® at Designated SNP Sites to Detect Allelic Expression Imbalance and Loss-of-Heterozygosity.

M. Hitchins, C. Kwok, 2015, Methods in molecular biology.

Epigenetic inactivation of a cluster of genes flanking MLH1 in microsatellite-unstable colorectal cancer.

S. Clark, R. Ward, N. Hawkins, 2007, Cancer research.

Integrated Genetic, Epigenetic, and Transcriptional Profiling Identifies Molecular Pathways in the Development of Laterally Spreading Tumors

M. A. Sloane, L. Hesson, D. Beck, 2016, Molecular Cancer Research.

RBM3 regulates temperature sensitive miR-142–5p and miR-143 (thermomiRs), which target immune genes and control fever

Amy Y. M. Au, U. Schmitz, W. Ritchie, 2016, Nucleic acids research.

Dominantly inherited constitutional epigenetic silencing of MLH1 in a cancer-affected family is linked to a single nucleotide variant within the 5'UTR.

R. Ward, J. Goldblatt, L. Khachigian, 2011, Cancer cell.