A. Scott

发表

4-Amino-2-[4-[1-(benzyloxycarbonyl)-2(S)- [[(1,1-dimethylethyl)amino]carbonyl]-piperazinyl]-6, 7-dimethoxyquinazoline (L-765,314): a potent and selective alpha1b adrenergic receptor antagonist.

M. Bock, R. Chang, M. Patane, 1998, Journal of medicinal chemistry.

Cyclic food restriction, insulin and mammary cell proliferation in the rat.

L. Meeker, H. Thompson, A. Scott, 1997, Carcinogenesis.

BRL 34915 (cromakalim) activates ATP-sensitive K+ current in cardiac muscle.

M. Sanguinetti, P. Siegl, A. Scott, 1988, Proceedings of the National Academy of Sciences of the United States of America.

4-Oxospiro[benzopyran-2,4′-piperidines] as selective α1a-adrenergic receptor antagonists

M. Bock, R. Chang, T. Broten, 1999 .

Design and synthesis of N-alkylated saccharins as selective α-1a adrenergic receptor antagonists☆

R. Chang, Tsing-bau Chen, J. Huff, 1998 .

Leukotriene D4 increases both the force of contraction and polyphosphoinositide formation in guinea-pig papillary muscle.

P. Siegl, D. Aharony, A. Scott, 1991, European journal of pharmacology.

Enhanced release of atrial natriuretic factor by endothelin in atria from hypertensive rats.

G. Vlasuk, R. Winquist, A. Scott, 1989, Hypertension.

Cardiac angiotensin receptors: effects of selective angiotensin II receptor antagonists, DUP 753 and PD 121981, in rabbit heart.

R. Chang, P. Siegl, V. Lotti, 1992, The Journal of pharmacology and experimental therapeutics.

Mechanism of Action

M. Sanguinetti, N. Jurkiewicz, P. Siegl, 2005 .

Isoproterenol antagonizes prolongation of refractory period by the class III antiarrhythmic agent E-4031 in guinea pig myocytes. Mechanism of action.

M. Sanguinetti, N. Jurkiewicz, P. Siegl, 1991, Circulation research.

Interactions of DPI 201-106, a novel cardiotonic agent, with cardiac calcium channels

G. Kaczorowski, P. Siegl, G. Morgan, 1988, Naunyn-Schmiedeberg's Archives of Pharmacology.

Negative lusitropic effect of DPI 201-106 and E4031. Possible role of prolonging action potential duration.

H. Cingolani, J. Lynch, P. Siegl, 1990, Journal of molecular and cellular cardiology.

Cyclic food restriction alters substrate utilization and abolishes protection from mammary carcinogenesis female rats.

L. Meeker, H. Thompson, D. Sinha, 1996, The Journal of nutrition.

3-(1-piperazinyl)-4,5-dihydro-1H-benzo[g]indazoles: high affinity ligands for the human dopamine D4 receptor with improved selectivity over ion channels.

P. Leeson, I. Collins, M. Rowley, 1998, Bioorganic & medicinal chemistry.

Cardiac angiotensin receptors: effects of selective angiotensin II receptor antagonists, DUP 753 and PD 121981, in rabbit heart.

V. Lotti, A. Scott, Peter K. S. Siegl, 1992, The Journal of pharmacology and experimental therapeutics.