Meng Wang

发表

A Naturally-Occurring Dominant-Negative Inhibitor of Keap1 Competitively against Its Negative Regulation of Nrf2

Yiguo Zhang, Yu-ping Zhu, L. Qiu, 2018, International journal of molecular sciences.

Distinct isoforms of Nrf1 diversely regulate different subsets of its cognate target genes

Yiguo Zhang, Xufang Ru, L. Qiu, 2018, Scientific Reports.

Distinct isoforms of Nrf1 diversely regulate different subsets of its cognate target genes

Yiguo Zhang, Xufang Ru, L. Qiu, 2018, bioRxiv.

Nrf1 is an indispensable redox-determining factor for mitochondrial homeostasis by integrating multi-hierarchical regulatory networks

Yiguo Zhang, Shaofan Hu, Reziyamu Wufuer, 2022, bioRxiv.

Nrf1 is an indispensable redox-determining factor for mitochondrial homeostasis by integrating multi-hierarchical regulatory networks

Yiguo Zhang, Shaofan Hu, Reziyamu Wufuer, 2022, bioRxiv.

Activation of the membrane-bound Nrf1 transcription factor by USP19, a ubiquitin-specific protease C-terminally anchored in the endoplasmic reticulum.

Yiguo Zhang, Shaofan Hu, L. Qiu, 2022, Biochimica et biophysica acta. Molecular cell research.

Activation of the membrane-bound Nrf1 transcription factor by USP19, a ubiquitin-specific protease C-terminally tail-anchored in the endoplasmic reticulum

Yiguo Zhang, Shaofan Hu, L. Qiu, 2020, bioRxiv.

Nrf1D Is the First Candidate Secretory Transcription Factor in the Blood Plasma, Its Precursor Existing as a Unique Redox-Sensitive Transmembrane CNC-bZIP Protein in Hemopoietic and Somatic Tissues

Yiguo Zhang, Shaofan Hu, L. Qiu, 2018, bioRxiv.

The inflammatory accumulation of lipids and ROS in human Nrf1α-deficient hepatoma cells is ameliorated by 2-bromopalmitate

Yiguo Zhang, Shaofan Hu, Ze Zheng, 2021 .

Nrf1 is not a direct target gene of SREBP1, albeit both are integrated into the rapamycin-responsive regulatory network in human hepatoma cells

Yiguo Zhang, Shaofan Hu, L. Qiu, 2022, bioRxiv.

Nrf1 Is Endowed with a Dominant Tumor-Repressing Effect onto the Wnt/β-Catenin-Dependent and Wnt/β-Catenin-Independent Signaling Networks in the Human Liver Cancer

Yiguo Zhang, Jiayu Chen, Xufang Ru, 2020, Oxidative medicine and cellular longevity.

Nrf1 Is Endowed with a Dominant Tumor-Repressing Effect onto the Wnt/β-Catenin-Dependent and Wnt/β-Catenin-Independent Signaling Networks in the Human Liver Cancer

Yiguo Zhang, Jiayu Chen, Xufang Ru, 2019, bioRxiv.

A naturally-occurring dominant-negative competitor of Keap1 against its inhibition of Nrf2

Yiguo Zhang, Yu-ping Zhu, L. Qiu, 2018, bioRxiv.

Nach Is a Novel Subgroup at an Early Evolutionary Stage of the CNC-bZIP Subfamily Transcription Factors from the Marine Bacteria to Humans

Xiaomei Zhu, Yiguo Zhang, P. Mattjus, 2018, International journal of molecular sciences.

Nach is a novel ancestral subfamily ofthe CNC-bZIP transcription factors selected during evolution from the marine bacteria to human

Yiguo Zhang, P. Mattjus, Shaofan Hu, 2018, bioRxiv.

TCF11 Has a Potent Tumor-Repressing Effect Than Its Prototypic Nrf1α by Definition of Both Similar Yet Different Regulatory Profiles, With a Striking Disparity From Nrf2

Yiguo Zhang, Shaofan Hu, L. Qiu, 2021, bioRxiv.

Nrf1D is the first candidate secretory transcription factor in the blood plasma, with its precursor existing as a unique redox-sensitive transmembrane CNC-bZIP protein in somatic tissues

Yiguo Zhang, Shaofan Hu, L. Qiu, 2018, bioRxiv.

Mechanisms controlling the multistage post‐translational processing of endogenous Nrf1&agr;/TCF11 proteins to yield distinct isoforms within the coupled positive and negative feedback circuits

J. Pi, Yiguo Zhang, Siwang Yu, 2018, Toxicology and applied pharmacology.

Molecular mechanisms controlling the multistage post-translational processing of endogenous Nrf1α/TCF11 proteins to yield distinct proteoforms within the coupled positive and negative feedback circuits

J. Pi, Yiguo Zhang, Siwang Yu, 2018, bioRxiv.

Oncogenic Activation of Nrf2, Though as a Master Antioxidant Transcription Factor, Liberated by Specific Knockout of the Full-Length Nrf1α that Acts as a Dominant Tumor Repressor

Yiguo Zhang, Siwang Yu, Shaofan Hu, 2018, Cancers.

Oncogenic activation of Nrf2 by specific knockout of Nrf1α that acts as a dominant tumor repressor

Yiguo Zhang, Siwang Yu, Shaofan Hu, 2018, bioRxiv.

Ketogenic diet: new avenues to overcome colorectal cancer

Yuancai Xiang, Hongming Miao, Meng Wang, 2022, Signal Transduction and Targeted Therapy.

Topovectorial mechanisms control the juxtamembrane proteolytic processing of Nrf1 to remove its N-terminal polypeptides during maturation of the CNC-bZIP factor

Yiguo Zhang, P. Mattjus, Shaofan Hu, 2018, bioRxiv.

Topovectorial mechanisms control the juxtamembrane proteolytic processing of Nrf1 to remove its N-terminal polypeptides during maturation of the CNC-bZIP factor

Yiguo Zhang, P. Mattjus, Shaofan Hu, 2018, bioRxiv.

A potent tumour-suppressor TCF11, than its prototypic Nrf1, is defined by similar yet different regulatory profiles of both isoforms, with a striking disparity from Nrf2

Yiguo Zhang, Shaofan Hu, L. Qiu, 2021 .

Distinct mechanisms by which antioxidant transcription factors Nrf1 and Nrf2 as drug targets contribute to the anticancer efficacy of Cisplatin on hepatoma cells

Jingfeng, Yiguo Zhang, Shaofan Hu, 2023, bioRxiv.

Loss of Nrf1 rather than Nrf2 leads to inflammatory accumulation of lipids and reactive oxygen species (ROS) in human hepatoma cells, which is alleviated by 2-bromopalmitate

Shaofan Hu, Ze Zheng, Meng Wang, 2021, bioRxiv.

Distinct mechanisms by which Nrf1 and Nrf2 as drug targets contribute to the anticancer efficacy of cisplatin on hepatoma cells.

Shaofan Hu, Reziyamu Wufuer, Meng Wang, 2024, Free radical biology & medicine.

Genetic loss of Nrf1 and Nrf2 leads to distinct metabolism reprogramming of HepG2 cells by opposing regulation of the PI3K-AKT-mTOR signalling pathway.

Shaofan Hu, Yu-ping Zhu, Meng Wang, 2024, Bioorganic chemistry.

Deletion of Nrf1 exacerbates oxidative stress-induced cellular senescence by disrupting the cell homeostasis

Shaofan Hu, L. Qiu, Meng Wang, 2024, bioRxiv.