C. Simm

发表

High-Throughput Screen for Identifying Small Molecules That Target Fungal Zinc Homeostasis

C. Luan, T. O’Halloran, E. Weiss, 2011, PloS one.

Disruption of Iron Homeostasis and Mitochondrial Metabolism Are Promising Targets to Inhibit Candida auris

A. Traven, T. Beilharz, P. Harrison, 2022, Microbiology spectrum.

Zinc and Iron Homeostasis: Target-Based Drug Screening as New Route for Antifungal Drug Development

R. May, C. Simm, 2019, Front. Cell. Infect. Microbiol..

Zinc and Iron Homeostasis

R. May, C. Simm, 2019 .

Schizosaccharomyces pombe as a model for metal homeostasis in plant cells: the phytochelatin-dependent pathway is the main cadmium detoxification mechanism.

S. Clemens, C. Simm, 2003, The New phytologist.

Saccharomyces cerevisiae Vacuole in Zinc Storage and Intracellular Zinc Distribution

B. Yandell, D. Eide, D. Salt, 2007, Eukaryotic Cell.

Candida auris evades innate immunity by using metabolic strategies to escape and kill macrophages while avoiding antimicrobial inflammation

R. Ben-Ami, D. Shasha, M. Speir, 2023, bioRxiv.

Heavy Metal‐binding Proteins and Peptides

T. Maier, S. Clemens, C. Simm, 2003 .

Candida auris uses metabolic strategies to escape and kill macrophages while avoiding robust activation of the NLRP3 inflammasome response.

R. Ben-Ami, D. Shasha, Daniel S. Simpson, 2023, Cell reports.

Loss of Zhf and the tightly regulated zinc-uptake system SpZrt1 in Schizosaccharomyces pombe reveals the delicacy of cellular zinc balance.

Ute Krämer, S. Clemens, C. Simm, 2008, FEMS yeast research.

Leveraging the MMV Pathogen Box to Engineer an Antifungal Compound with Improved Efficacy and Selectivity against Candida auris.

C. Simm, Harshini Weerasinghe, Ana Traven, 2023, ACS infectious diseases.