W. Schrader

发表

Molecular actions of steroid hormones.

B. O’Malley, M. Tsai, W. Schrader, 1986, Advances in Experimental Medicine and Biology.

Meclizine is an agonist ligand for mouse constitutive androstane receptor (CAR) and an inverse agonist for human CAR.

D. Moore, P. Wei, Wendong Huang, 2004, Molecular endocrinology.

Photocytotoxicity of the Fluorescent Nonsteroidal Androgen Receptor Ligand TDPQ †

C. Chignell, P. Bilski, W. Schrader, 2009, Photochemistry and photobiology.

Interaction of the chicken progesterone receptor with heat shock protein (HSP) 90.

B. O’Malley, O. Conneely, A. T. Lee, 1989, Journal of steroid biochemistry.

Selective binding of chicken progesterone receptor A subunit to a DNA fragment containing ovalbumin gene sequences.

B. O’Malley, J. Compton, W. Schrader, 1982, Biochemical and biophysical research communications.

Studies on the structure and function of the chicken progesterone receptor.

W. Grody, B. O’Malley, N. Weigel, 1981, Recent progress in hormone research.

Chicken progesterone receptor expressed in Saccharomyces cerevisiae is correctly phosphorylated at all four Ser-Pro phosphorylation sites.

B. O’Malley, N. Weigel, O. Conneely, 1993, Biochemistry.

Potent, nonsteroidal selective androgen receptor modulators (SARMs) based on 8H-[1,4]oxazino[2,3-f]quinolin-8-ones.

J. Edwards, E. Kallel, D. Karanewsky, 2007, Bioorganic & medicinal chemistry letters.

Structural analysis of chicken oviduct progesterone receptor using monoclonal antibodies to the subunit B protein.

D. Edwards, W. McGuire, B. O’Malley, 1984, Biochemistry.

The receptors of steroid hormones.

B. O’Malley, W. Schrader, 1976, Scientific American.

The A and B forms of the chicken progesterone receptor arise by alternate initiation of translation of a unique mRNA.

B. O’Malley, O. Conneely, D. Toft, 1987, Biochemical and biophysical research communications.

Differential hormone-dependent phosphorylation of progesterone receptor A and B forms revealed by a phosphoserine site-specific monoclonal antibody.

D. Edwards, N. Weigel, L. Sherman, 2000, Molecular endocrinology.

5-benzylidene-1,2-dihydrochromeno[3,4-f]quinolines as selective progesterone receptor modulators.

J. Edwards, B. Pio, T. K. Jones, 2003, Journal of medicinal chemistry.

Hormonal regulation and identification of chicken progesterone receptor phosphorylation sites.

B. O’Malley, N. Weigel, L. Denner, 1990, The Journal of biological chemistry.

The production of androgen binding protein by Sertoli Cells.

D. Tindall, A. Means, W. Schrader, 1974, Current topics in molecular endocrinology.

Activation, transformation, and subunit structure of steroid hormone receptors.

W. Grody, B. O’Malley, W. Schrader, 1982, Endocrine reviews.

The structure and function of the progesterone receptor

W. Grody, B. O’Malley, N. Weigel, 1981 .

Kinetics of progesterone binding to the chick oviduct receptor protein.

B. O’Malley, A. Johnson, W. Schrader, 1976, Journal of steroid biochemistry.

Progesterone-binding components of chick oviduct. IV. Characterization of purified subunits.

B. O’Malley, W. Schrader, 1972, The Journal of biological chemistry.

Molecular cloning of the chicken progesterone receptor

B. O’Malley, R. Cook, G. Greene, 1986, Science.

Progesterone-binding components of chick oviduct. VIII. Receptor activation and hormone-dependent binding to purified nuclei.

B. O’Malley, R. Buller, D. Toft, 1975, The Journal of biological chemistry.

DNA sequence preference of the progesterone receptor.

B. O’Malley, J. Compton, W. Schrader, 1983, Proceedings of the National Academy of Sciences of the United States of America.

Progesterone-binding components of chick oviduct. Biochemical characterization of purified oviduct progesterone receptor B subunit.

R. W. Kuhn, B. O’Malley, W. Coty, 1977, The Journal of biological chemistry.

Progesterone-binding components of chick oviduct: partial purification and characterization of a calcium-activated protease which hydrolyzes the progesterone receptor.

B. O’Malley, W. Vedeckis, W. Schrader, 1980, Biochemistry.

Progesterone-binding components of chick oviduct. IX. The kinetics of nuclear binding.

B. O’Malley, R. Buller, W. Schrader, 1975, The Journal of biological chemistry.

Structure-function properties of the chicken progesterone receptor A synthesized from complementary deoxyribonucleic acid.

M. Carson, B. O’Malley, M. Tsai, 1987, Molecular endocrinology.

Photoaffinity labeling of the chick progesterone receptor proteins. Similar hormone binding domains detected after removal of proteolytic interference.

B. O’Malley, W. Schrader, M. Birnbaumer, 1983, Journal of Biological Chemistry.

Chemical cross-linking of chick oviduct progesterone-receptor subunits by using a reversible bifunctional cross-linking agent.

B. O’Malley, W. Schrader, M. Birnbaumer, 1979, The Biochemical journal.

Progesterone-binding components of chick oviduct. In vitro effect of receptor subunits on gene transcription.

R. Schwartz, B. O’Malley, R. Buller, 1976, The Journal of biological chemistry.

Progesterone receptors of chick oviduct: identification of 6S receptor dimers.

B. O’Malley, W. Schrader, S. Heuer, 1975, Biology of reproduction.

Progesterone-binding protein of chick oviduct. VI. Interaction of purified progesterone-receptor components with nuclear constituents.

B. O’Malley, D. Toft, W. Schrader, 1972, The Journal of biological chemistry.

High level expression of a truncated chicken progesterone receptor in Escherichia coli.

B. O’Malley, T. Butt, O. Conneely, 1990, The Journal of biological chemistry.

Protein kinases of the chick oviduct: a study of the cytoplasmic and nuclear enzymes.

B. O’Malley, T. Chandra, R. Keller, 1976, Biochemistry.

[17] Methods for extraction and quantification of receptors

W. Schrader, 1975 .

Hormone-induced changes in the in vitro DNA-binding activity of the chicken progesterone receptor.

M. Carson, B. O’Malley, N. Weigel, 1989, Molecular endocrinology.

Assessment of structural similarities in chick oviduct progesterone receptor subunits by partial proteolysis of photoaffinity-labeled proteins.

B. O’Malley, W. Schrader, M. Birnbaumer, 1983, The Journal of biological chemistry.

Chemical and antigenic properties of pure 108,000 molecular weight chick progesterone receptor.

B. O’Malley, R. Cook, W. Schrader, 1987, Molecular endocrinology.

Hormone-dependent regulation of chicken progesterone receptor deoxyribonucleic acid binding and phosphorylation.

B. O’Malley, N. Weigel, L. Denner, 1989, Endocrinology.

The chicken progesterone receptor A and B isoforms are products of an alternate translation initiation event.

B. O’Malley, M. Tsai, O. Conneely, 1989, The Journal of biological chemistry.

Purification and characterization of the chick oviduct progesterone receptor A subunit.

B. O’Malley, W. Coty, W. Schrader, 1979, Journal of steroid biochemistry.

Progesterone-binding components of chick oviduct. Receptor B subunit protein purified to apparent homogeneity from laying hen oviducts.

R. W. Kuhn, B. O’Malley, W. Schrader, 1977, The Journal of biological chemistry.

Novel series of potent, nonsteroidal, selective androgen receptor modulators based on 7H-[1,4]oxazino[3,2-g]quinolin-7-ones.

Dale E Mais, James P Edwards, J. Edwards, 2007, Journal of medicinal chemistry.

Regulation of progesterone receptor-mediated transcription by phosphorylation.

B. O’Malley, N. Weigel, L. Denner, 1990, Science.

Preparation, resolution, and biological evaluation of 5-aryl-1, 2-dihydro-5H-chromeno[3,4-f]quinolines: potent, orally active, nonsteroidal progesterone receptor agonists.

J. Edwards, M. Gottardis, C. Pathirana, 1998, Journal of medicinal chemistry.

An orally active selective androgen receptor modulator is efficacious on bone, muscle, and sex function with reduced impact on prostate.

Russell Turner, William Schrader, R. Turner, 2007, Endocrinology.

Discovery of 6-N,N-bis(2,2,2-trifluoroethyl)amino- 4-trifluoromethylquinolin-2(1H)-one as a novel selective androgen receptor modulator.

Arjan van Oeveren, Mehrnouch Motamedi, Neelakandha S Mani, 2006, Journal of medicinal chemistry.

Synthesis and biological activity of 5-methylidene 1,2-dihydrochromeno[3,4-f]quinoline derivatives as progesterone receptor modulators.

J. Edwards, B. Pio, T. K. Jones, 2003, Bioorganic & medicinal chemistry letters.

Development of progesterone receptor antagonists from 1,2-dihydrochromeno[3,4-f]quinoline agonist pharmacophore.

J. Edwards, B. Pio, T. K. Jones, 2003, Bioorganic & medicinal chemistry letters.

Sequence and expression of a functional chicken progesterone receptor.

B. O’Malley, M. Tsai, O. Conneely, 1987, Molecular endocrinology.

Structural relationships between the chick oviduct progesterone receptor A and B proteins.

B. O’Malley, W. Vedeckis, W. Schrader, 1979, Advances in Experimental Medicine and Biology.

Progesterone binding components of chick oviduct. X. Purification by affinity chromatography.

R. W. Kuhn, B. O’Malley, R. Smith, 1975, The Journal of biological chemistry.

Mechanisms of Interaction of a Hormone—Receptor Complex with the Genome of a Eukaryotic Target Cell

B. O’Malley, F. Chytil, T. Spelsberg, 1972, Nature.

Steroid Receptor Subunit Structure

B. O’Malley, W. Vedeckis, W. Schrader, 1980 .

CHAPTER 8 – The Chick Oviduct Progesterone Receptor

B. O’Malley, W. Vedeckis, W. Schrader, 1978 .

Phosphorylation of hen progesterone receptor by cAMP dependent protein kinase.

B. O’Malley, N. Weigel, J. Tash, 1981, Biochemical and biophysical research communications.

Dimerization of the chicken progesterone receptor in vitro can occur in the absence of hormone and DNA.

B. O’Malley, N. Weigel, W. Schrader, 1990, Molecular endocrinology.

A Specific Oviduct Target-Tissue Receptor For Progesterone: Identification, Characterization, Partial Purification, Inter-Compartmental Transfer Kinetics and Specific Interaction with the Genome

B. O’Malley, D. Toft, T. Spelsberg, 1971 .

Molecular mechanism of action of a steroid hormone receptor.

B. O’Malley, M. Tsai, S. Tsai, 1991, Recent progress in hormone research.

An alternative ligand-independent pathway for activation of steroid receptors.

B. O’Malley, Carolyn L. Smith, N. Weigel, 1995, Recent progress in hormone research.

The progesterone receptor stimulates cell-free transcription by enhancing the formation of a stable preinitiation complex

B. O’Malley, L. Klein-Hitpass, S. Tsai, 1990, Cell.

Endocrinology: New model for steroid hormone receptors?

W. Schrader, 1984, Nature.

Progesterone receptor interaction in the 5'-flanking regulatory region of the ovalbumin gene.

B. O’Malley, W. Schrader, J. G. Comptom, 1986, Advances in experimental medicine and biology.

Progesterone receptor binding to DNA: studies by sedimentation velocity methods.

B. O’Malley, J. Compton, W. Schrader, 1984, Journal of steroid biochemistry.

Steroid receptor family: structure and functions.

B. O’Malley, W. Schrader, M. A. Carson-Jurica, 1990, Endocrine reviews.

Covalent attachment of a progestational steroid to chick oviduct progesterone receptor by photoaffinity labelling

B. O’Malley, L. Dure, W. Schrader, 1980, Nature.

Androgen receptor-mediated apoptosis is regulated by photoactivatable androgen receptor ligands.

P. Bilski, A. Rice, W. Schrader, 2008, Molecular endocrinology.

Identification of the DNA-Binding Domain of the Chicken Progesterone Receptor A Subunit

B. O’Malley, N. Weigel, W. Schrader, 1983 .

Oviduct progesterone receptor: physical and chemical studies.

W. Schrader, 1982, Metabolism: clinical and experimental.

Structure of chick progesterone receptors.

B. O’Malley, W. Schrader, 1978, Cancer research.

Steroids and the practical aspects of performing binding studies.

R. Buller, W. Schrader, B. W. O'Maller, 1976, Journal of steroid biochemistry.

Purification of chick oviduct progesterone receptor apoprotein.

B. O’Malley, A. Maggi, M. Fahnestock, 1981, Journal of steroid biochemistry.

Laboratory methods manual for hormone action and molecular endocrinology

B. O’Malley, W. Schrader, 1978 .

Molecular Structure and Analysis of Progesterone Receptors

B. O’Malley, W. Schrader, 1978 .

Hormone-receptor interactions with the genome of eucaryotic target cells.

B. O’Malley, T. Spelsberg, W. Schrader, 1973, Advances in experimental medicine and biology.

[27] Steroid hormone-receptor interactions with nuclear constituents

R. Buller, S. H. Socher, W. Schrader, 1975 .

Progesterone receptor components: identification of subunits binding to the target-cell genome.

B. O’Malley, W. Schrader, 1972, Journal of steroid biochemistry.

High-yield high-performance liquid chromatographic analysis of steroid hormone receptors on glass columns.

B. O’Malley, N. Weigel, L. Denner, 1987, Analytical biochemistry.

New model for steroid hormone receptors?

W. Schrader, 1984, Nature.

A review of regulation of gene expression by steroid hormone receptors.

R. Schwartz, B. O’Malley, W. Schrader, 1976, Journal of steroid biochemistry.

EFFECT OF PROGESTERONE RECEPTORS ON TRANSCRIPTION *

R. Schwartz, B. O’Malley, W. Schrader, 1977, Annals of the New York Academy of Sciences.

Progesterone-binding components of chick oviduct. In vitro effects of purified hormone-receptor complexes on the initiation of RNA synthesis in chromatin.

R. W. Kuhn, R. Schwartz, B. O’Malley, 1976, The Journal of biological chemistry.

The mechanism of RU486 antagonism is dependent on the conformation of the carboxy-terminal tail of the human progesterone receptor

B. O’Malley, M. Tsai, G. Allan, 1992, Cell.

Interaction of the chick oviduct progesterone receptor with deoxyribonucleic acid.

B. O’Malley, J. Compton, M. Hughes, 1981, Biochemistry.

Monoclonal antibody to the hen oviduct progesterone receptor produced following in vitro immunization.

B. O’Malley, M. Tsai, S. Tsai, 1984, Journal of steroid biochemistry.

Progesterone-binding components of chick oviduct: analysis of receptor structure by limited proteolysis.

B. O’Malley, W. Vedeckis, W. Schrader, 1980, Biochemistry.

Differential sensitivity of chicken progesterone receptor forms to sulfhydryl reactive reagents.

B. O’Malley, S. Peleg, W. Schrader, 1989, Biochemistry.

Sulfhydryl group content of chicken progesterone receptor: effect of oxidation on DNA binding activity.

B. O’Malley, S. Peleg, W. Schrader, 1988, Biochemistry.

Chicken progesterone receptor is phosphorylated by a DNA-dependent protein kinase during in vitro transcription assays.

B. O’Malley, N. Weigel, T. Carter, 1992, Molecular endocrinology.

Expression of functional chicken oviduct progesterone receptors in yeast (Saccharomyces cerevisiae).

B. O’Malley, N. Weigel, P. Mak, 1989, The Journal of biological chemistry.

A novel, highly regulated, rapidly inducible system for the expression of chicken progesterone receptor, cPRA, in Saccharomyces cerevisiae.

B. O’Malley, N. Weigel, O. Conneely, 1992, Gene.

Mutational analysis of the chicken progesterone receptor.

B. O’Malley, M. Tsai, O. Conneely, 1989, The Journal of biological chemistry.

Progesterone-binding sites of the chick oviduct receptor. Presence of a weaker ligand site which is destroyed by phosphatase treatment.

B. O’Malley, A. Maggi, W. Schrader, 1984, The Journal of biological chemistry.

Inactivation of chick oviduct progesterone receptors.

W. Grody, B. O’Malley, J. Compton, 1980, Journal of steroid biochemistry.

Progesterone receptors of chick oviduct.

B. O’Malley, W. Schrader, 1978, Advances in experimental medicine and biology.

Antibodies to chicken progesterone receptor peptide 523-536 recognize a site exposed in receptor-deoxyribonucleic acid complexes but not in receptor-heat shock protein-90 complexes.

B. O’Malley, N. Weigel, W. Schrader, 1989, Endocrinology.

Immunologic detection of a protein homologous to chicken progesterone receptor B subunit.

D. Edwards, W. McGuire, B. O’Malley, 1985, The Journal of biological chemistry.

Reversible dissociation of chick oviduct progesterone receptor subunits.

W. Grody, B. O’Malley, W. Schrader, 1986, Advances in experimental medicine and biology.

Progesterone Receptor Binding to the Ovalbumin Gene

B. O’Malley, J. Compton, W. Schrader, 1984 .

MECHANISM OF STEROID HORMONE ACTION: IN VITRO CONTROL OF GENE EXPRESSION IN CHICK OVIDUCT CHROMATIN BY PURIFIED STEROID RECEPTOR COMPLEXES

R. Schwartz, B. O’Malley, W. Schrader, 1976 .

Structure-function relationships of the chicken progesterone receptor.

M. Carson, B. O’Malley, M. Tsai, 1988, Biochemical Society transactions.

Purification and Properties of Progesterone Receptors from Chick Oviduct *

B. O’Malley, Roy G. Smith, W. Coty, 1977, Annals of the New York Academy of Sciences.

Methods for extraction and quantification of receptors.

W. Schrader, 1975, Methods in enzymology.

Cooperative Interactions of Steroid Receptors at Their Target Enhancers

B. O’Malley, M. Tsai, S. Tsai, 1989 .

Amino acid sequence of a chicken heat shock protein derived from the complementary DNA nucleotide sequence.

M. Kulomaa, B. O’Malley, C. March, 1986, Biochemistry.

Molecular cloning of a cDNA for the chicken progesterone receptor B antigen.

D. Edwards, W. McGuire, M. Kulomaa, 1984, Proceedings of the National Academy of Sciences of the United States of America.

Androgen receptor-mediated apoptosis is regulated by photoactivatable androgen receptor ligands.

P. Bilski, A. Rice, W. Schrader, 2008, Molecular endocrinology.