Y. Lai

发表

Phosphoproteomic screening identifies Rab GTPases as novel downstream targets of PINK1

J. Corvol, D. Campbell, M. Peggie, 2015, The EMBO journal.

Resource Phosphoproteomic screening identifies Rab GTPases as novel downstream targets of PINK 1

J. Corvol, D. Campbell, M. Peggie, 2015 .

Regulatory Roles of PINK1-Parkin and AMPK in Ubiquitin-Dependent Skeletal Muscle Mitophagy

Y. Lai, A. Seabright, Alex P. Seabright, 2020, Frontiers in Physiology.

Effects of hiking at altitude on body composition and insulin sensitivity in recovering drug addicts.

Y. Liao, C. Kuo, Y. Lai, 2004, Preventive medicine.

properties in epitrochlearis muscles from lean and obese Zucker rats Effect of insulin and contraction on glycogen synthase phosphorylation and kinetic

R. Eckel, E. Melanson, James O. Hill, 2015 .

Effects of adrenaline on whole-body glucose metabolism and insulin-mediated regulation of glycogen synthase and PKB phosphorylation in human skeletal muscle.

J. Eriksson, J. Jensen, T. Ruge, 2011, Metabolism: clinical and experimental.

Regulation of muscle glycogen synthase phosphorylation and kinetic properties by insulin, exercise, adrenaline and role in insulin resistance

J. Jensen, Y. Lai, 2009, Archives of physiology and biochemistry.

Insulin action and signalling in fat and muscle from dexamethasone-treated rats.

J. Burén, J. Eriksson, Jenny Casey Eriksson, 2008, Archives of biochemistry and biophysics.

Characteristics of glycemic control in elite power and endurance athletes.

S. Chou, C. Kuo, Y. Lai, 2005, Preventive medicine.

glycogen contents uptake and glycogen synthase in muscle with different Additive effect of contraction and insulin on glucose

P. Poulsen, A. Vaag, H. Beck-Nielsen, 2015 .

Additive effect of contraction and insulin on glucose uptake and glycogen synthase in muscle with different glycogen contents.

Elham Zarrinpashneh, J. Jensen, Y. Lai, 2010, Journal of applied physiology.

Exercise mediates ubiquitin signalling in human skeletal muscle

Y. Lai, Samuel O. Lord, 2022, FASEB bioAdvances.

Glycogen loading alters muscle glycogen resynthesis

G. Heigenhauser, K. Petersen, D. Rothman, 2015 .

Insulin-stimulated glycogen synthesis and glycogen synthase activation after electrical stimulation of epitrochlearis muscles with different initial glycogen contents

J. Jensen, C. Kuo, Y. Lai, 2010, Archives of physiology and biochemistry.

Ubiquitin E3 ligase Atrogin-1 protein is regulated via the rapamycin-sensitive mTOR-S6K1 signaling pathway in C2C12 muscle cells.

Y. Lai, Samuel O. Lord, Yusuke Nishimura, 2022, American journal of physiology. Cell physiology.

The Effect of Ex Vivo Human Serum from Liver Disease Patients on Cellular Protein Synthesis and Growth

J. Lord, C. Greig, A. Dhaliwal, 2022, Cells.

Global Deletion of 11β-HSD1 Prevents Muscle Wasting Associated with Glucocorticoid Therapy in Polyarthritis

Simon W. Jones, M. Cooper, A. Filer, 2021, International journal of molecular sciences.

Glycogen content and contraction regulate glycogen synthase phosphorylation and affinity for UDP-glucose in rat skeletal muscles.

J. Jensen, C. Kuo, Y. Lai, 2007, American journal of physiology. Endocrinology and metabolism.

University of Dundee Kinetin Riboside and Its ProTides Activate the Parkinson ’ s Disease Associated PTEN-Induced Putative Kinase 1 ( PINK 1 ) Independent of Mitochondrial Depolarization

M. Muqit, Y. Mehellou, J. H. Tucker, 2017 .

β‐Adrenoceptor stimulation potentiates insulin‐stimulated PKB phosphorylation in rat cardiomyocytes via cAMP and PKA

J. Jensen, E. Sudar, Y. Lai, 2010, British journal of pharmacology.

Effect of insulin and contraction on glycogen synthase phosphorylation and kinetic properties in epitrochlearis muscles from lean and obese Zucker rats.

J. Ivy, K. Cumming, J. Jensen, 2012, American journal of physiology. Cell physiology.

Role of glycogen content on glucose uptake and glycogen synthase in skeletal muscles: The effect of contraction and insulin

Y. Lai, 2010 .

Glycogen content regulates insulin‐ but not contraction‐mediated glycogen synthase activation in the rat slow‐twitch soleus muscles

J. Jensen, Y. Lai, F. Lin, 2009, Acta physiologica.

AMPK activation induces mitophagy and promotes mitochondrial fission while activating TBK1 in a PINK1‐Parkin independent manner

D. Hardie, D. Hardie, D. Hodson, 2020, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

The Role of UBE2-Conjugating Enzymes in the Mechanism of MuRF1 Ubiquitylation

S. Bodine, Leslie M. Baehr, T. Knowles, 2022, bioRxiv.

but not insulin receptor signaling in obese Zucker rats Exercise training improves muscle insulin resistance

L. Mandarino, Wanyi Wang, J. Ivy, 2015 .

The role of dehydroepiandrosterone levels on physiologic acclimatization to chronic mountaineering activity.

C. Kuo, Y. Lai, Shu-Man Chen, 2006, High altitude medicine & biology.

Effects of pharmacological AMP deaminase inhibition and Ampd1 deletion on nucleotide levels and AMPK activation in contracting skeletal muscle.

D. Vertommen, M. Bohlooly-y, M. Rider, 2014, Chemistry & biology.

Mature and immature β-cells both contribute to islet function and insulin release

G. Rutter, Ildem Akerman, L. Piemonti, 2020 .

Phosphatidylinositol 3-phosphate 5-kinase (PIKfyve) is an AMPK target participating in contraction-stimulated glucose uptake in skeletal muscle.

B. Viollet, D. Vertommen, F. Dequiedt, 2013, The Biochemical journal.

Kinetin Riboside and Its ProTides Activate the Parkinson’s Disease Associated PTEN-Induced Putative Kinase 1 (PINK1) Independent of Mitochondrial Depolarization

M. Muqit, Y. Mehellou, J. H. Tucker, 2017, Journal of medicinal chemistry.

PDX1LOW MAFALOW β-cells contribute to islet function and insulin release

G. Rutter, L. Piemonti, D. Hodson, 2021, Nature Communications.

A novel PKB/Akt inhibitor, MK-2206, effectively inhibits insulin-stimulated glucose metabolism and protein synthesis in isolated rat skeletal muscle.

M. Rider, Y. Lai, R. Jacobs, 2012, The Biochemical journal.

Benzimidazole derivative small-molecule 991 enhances AMPK activity and glucose uptake induced by AICAR or contraction in skeletal muscle

M. Foretz, M. Rider, K. Sakamoto, 2016, American journal of physiology. Endocrinology and metabolism.

Consumption of carbohydrate solutions enhances energy intake without increased body weight and impaired insulin action in rat skeletal muscles.

J. Ruzzin, J. Jensen, Y. Lai, 2005, Diabetes & metabolism.

Mammalian target of rapamycin-independent S6K1 and 4E-BP1 phosphorylation during contraction in rat skeletal muscle.

D. Vertommen, M. Rider, Y. Lai, 2013, Cellular signalling.

Nicotinamide Riboside Augments the Aged Human Skeletal Muscle NAD+ Metabolome and Induces Transcriptomic and Anti-inflammatory Signatures

Mark S. Schmidt, N. Jenkinson, C. Brenner, 2019, Cell reports.

PINK1-dependent phosphorylation of Serine111 within the SF3 motif of Rab GTPases impairs effector interactions and LRRK2-mediated phosphorylation at Threonine72

M. Sattler, M. Groll, R. Toth, 2019, bioRxiv.

stimulated electrically with different protocols Glucose uptake and metabolic stress in rat muscles

D. Vertommen, F. Dequiedt, J. Ivy, 2015 .

A small-molecule benzimidazole derivative that potently activates AMPK to increase glucose transport in skeletal muscle: comparison with effects of contraction and other AMPK activators.

B. Viollet, D. Vertommen, M. Foretz, 2014, The Biochemical journal.

Nicotinamide riboside augments the human skeletal muscle NAD+ metabolome and induces transcriptomic and anti-inflammatory signatures in aged subjects: a placebo-controlled, randomized trial

Mark S. Schmidt, N. Jenkinson, C. Brenner, 2019, bioRxiv.

The Role of Skeletal Muscle Glycogen Breakdown for Regulation of Insulin Sensitivity by Exercise

A. Kolnes, J. Jensen, P. I. Rustad, 2011, Front. Physio..

AMPK antagonizes hepatic glucagon-stimulated cyclic AMP signalling via phosphorylation-induced activation of cyclic nucleotide phosphodiesterase 4B

Ming‐Fei Hsu, B. Viollet, D. Vertommen, 2016, Nature Communications.

Probes of ubiquitin E3 ligases enable systematic dissection of parkin activation.

Cong Han, J. Corvol, M. Muqit, 2016, Nature chemical biology.

Probes of Ubiquitin E3 ligases distinguish different stages of Parkin activation

Cong Han, J. Corvol, M. Muqit, 2016, Nature chemical biology.

Author Correction: PDX1LOW MAFALOW β-cells contribute to islet function and insulin release

G. Rutter, L. Piemonti, D. Hodson, 2021, Nature Communications.

Ubiquitin E3 ligases Atrogin-1 and MuRF1 protein contents are differentially regulated in the rapamycin-sensitive mTOR-S6K1 signaling pathway in C2C12 myotubes

L. Holm, Y. Lai, I. Musa, 2021, bioRxiv.

Probes of Ubiquitin E3 ligases distinguish different stages of Parkin activation

Cong Han, J. Corvol, M. Muqit, 2016, Nature chemical biology.

GSK-3beta regulation in skeletal muscles by adrenaline and insulin: evidence that PKA and PKB regulate different pools of GSK-3.

P. Shepherd, J. Jensen, Y. Lai, 2007, Cellular signalling.

Mammalian target of rapamycin-independent S6K1 and 4E-BP1 phosphorylation during contraction in rat skeletal muscle.

D. Vertommen, M. Rider, Y. Lai, 2013, Cellular signalling.

Recent advances in measuring and understanding the regulation of exercise-mediated protein degradation in skeletal muscle.

L. Holm, Y. Lai, I. Musa, 2021, American journal of physiology. Cell physiology.