Niyada Hin

发表

Design, synthesis, and pharmacological evaluation of glutamate carboxypeptidase II (GCPII) inhibitors based on thioalkylbenzoic acid scaffolds.

D. Ferraris, T. Tsukamoto, B. Slusher, 2012, Journal of medicinal chemistry.

Thieno[2,3-d]pyrimidine-Based Positive Allosteric Modulators of Human Mas-Related G Protein-Coupled Receptor X1 (MRGPRX1).

Shaoqiu He, S. Raja, Xinzhong Dong, 2022, Journal of medicinal chemistry.

D-Amino-Acid Oxidase Inhibition Increases D-Serine Plasma Levels in Mouse But not in Monkey or Dog

D. Ferraris, T. Tsukamoto, B. Slusher, 2016, Neuropsychopharmacology.

Neutral sphingomyelinase 2 inhibitors based on the 4-(1H-imidazol-2-yl)-2,6-dialkoxyphenol scaffold.

Ondřej Štěpánek, T. Tsukamoto, B. Slusher, 2019, European journal of medicinal chemistry.

Synthesis of kojic acid derivatives as secondary binding site probes of D-amino acid oxidase.

D. Ferraris, T. Tsukamoto, B. Slusher, 2013, Bioorganic & medicinal chemistry letters.

Synthesis and SAR of 1-hydroxy-1H-benzo[d]imidazol-2(3H)-ones as Inhibitors of D-Amino Acid Oxidase.

K. Hashimoto, D. Ferraris, T. Tsukamoto, 2012, ACS medicinal chemistry letters.

Unprecedented Binding Mode of Hydroxamate-Based Inhibitors of Glutamate Carboxypeptidase II: Structural Characterization and Biological Activity.

J. Vávra, C. Bařinka, D. Ferraris, 2016, Journal of medicinal chemistry.

DPTIP, a newly identified potent brain penetrant neutral sphingomyelinase 2 inhibitor, regulates astrocyte-peripheral immune communication following brain inflammation

M. Ferrer, Noel Southall, Xin Hu, 2018, Scientific Reports.

D-Amino acid oxidase inhibitors based on the 5-hydroxy-1,2,4-triazin-6(1H)-one scaffold.

D. Ferraris, T. Tsukamoto, B. Slusher, 2016, Bioorganic & medicinal chemistry letters.

DPTIP, a newly identified potent brain penetrant neutral sphingomyelinase 2 inhibitor, regulates astrocyte-peripheral immune communication following brain inflammation

M. Ferrer, Noel Southall, Xin Hu, 2018, Scientific Reports.

6-Hydroxy-1,2,4-triazine-3,5(2H,4H)-dione Derivatives as Novel d-Amino Acid Oxidase Inhibitors

D. Ferraris, T. Tsukamoto, B. Slusher, 2015, Journal of medicinal chemistry.

Structural basis of interactions between human glutamate carboxypeptidase II and its substrate analogs.

J. Konvalinka, J. Lubkowski, M. Dauter, 2008, Journal of molecular biology.

Discovery of Benzamidine- and 1-Aminoisoquinoline-Based Human MAS-Related G-Protein-Coupled Receptor X1 (MRGPRX1) Agonists.

Xinzhong Dong, Tomoki Nishioka, T. Tsukamoto, 2019, Journal of medicinal chemistry.

Peptidomimetics of Arg-Phe-NH2 as small molecule agonists of Mas-related gene C (MrgC) receptors.

Xinzhong Dong, D. Ferraris, T. Tsukamoto, 2014, Bioorganic & medicinal chemistry.

Activation of MrgC receptor inhibits N-type calcium channels in small-diameter primary sensory neurons in mice

Qian Xu, Shaoqiu He, V. Tiwari, 2014, PAIN®.

MrgC agonism at central terminals of primary sensory neurons inhibits neuropathic pain

Qian Xu, Shaoqiu He, V. Tiwari, 2014, PAIN®.

Inhibition of xc⁻ transporter-mediated cystine uptake by sulfasalazine analogs.

D. Ferraris, T. Tsukamoto, B. Slusher, 2011, Bioorganic & medicinal chemistry letters.

High Throughput Screening Cascade To Identify Human Aspartate N-Acetyltransferase (ANAT) Inhibitors for Canavan Disease.

T. Tsukamoto, B. Slusher, C. Rojas, 2021, ACS Chemical Neuroscience.

Oral administration of D-alanine in monkeys robustly increases plasma and cerebrospinal fluid levels but experimental D-amino acid oxidase inhibitors had minimal effect

T. Tsukamoto, B. Slusher, R. Rais, 2016, Journal of psychopharmacology.

Structural and computational basis for potent inhibition of glutamate carboxypeptidase II by carbamate-based inhibitors.

L. Rulíšek, C. Bařinka, D. Ferraris, 2019, Bioorganic & medicinal chemistry.

Structural basis for potent inhibition of d-amino acid oxidase by thiophene carboxylic acids.

T. Tsukamoto, Y. Kato, B. Slusher, 2018, European journal of medicinal chemistry.

Neutral sphingomyelinase 2 inhibitors based on the pyrazolo[1,5-a]pyrimidin-3-amine scaffold.

K. Novotná, Ondřej Štěpánek, A. Pal, 2023, European journal of medicinal chemistry.