T. Okamura

发表

Attempts to Image MRP1 Function in the Blood-Brain Barrier Using the Metabolite Extrusion Method

Ming-Rong Zhang, T. Okamura, T. Kikuchi, 2020 .

OAT3-Mediated Extrusion of the 99mTc-ECD Metabolite in the Mouse Brain

Atsushi B. Tsuji, Ming-Rong Zhang, Joji Yui, 2014, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

A radiotracer method to study efflux transport of iodide liberated from thyroid hormones via deiodination metabolism in the brain.

K. Fukushi, T. Irie, Y. Arano, 2009, Life sciences.

Reactivity of 6-halopurine analogs with glutathione as a radiotracer for assessing function of multidrug resistance-associated protein 1.

K. Fukushi, T. Irie, T. Okamura, 2009, Journal of medicinal chemistry.

6-[124I]Iodo-9-pentylpurine for imaging the activity of the sodium iodide symporter in the brain.

Atsushi B. Tsuji, Ming-Rong Zhang, H. Ishii, 2020, Journal of medicinal chemistry.

Development of Purine-Derived 18F-Labeled Pro-drug Tracers for Imaging of MRP1 Activity with PET

M. Lythgoe, Ming-Rong Zhang, M. Koepp, 2014, Journal of medicinal chemistry.

Noninvasive and Quantitative Assessment of the Function of Multidrug Resistance-Associated Protein 1 in the Living Brain

K. Fukushi, T. Irie, M. Takei, 2009, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

An approach for measuring in vivo cerebral redox states using the oxidative conversion of dihydropyridine to pyridinium ion and the metabolic trapping principle.

K. Fukushi, T. Irie, Y. Arano, 2005, Free radical biology & medicine.

Imaging of activity of multidrug resistance-associated protein 1 in the lungs.

Ming-Rong Zhang, H. Wakizaka, Maki Okada, 2013, American journal of respiratory cell and molecular biology.

A 11C-Labeled 1,4-Dihydroquinoline Derivative as a Potential PET Tracer for Imaging of Redox Status in Mouse Brain

Ming-Rong Zhang, H. Wakizaka, Maki Okada, 2015, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Efficient synthesis and chiral separation of 11C-labeled ibuprofen assisted by DMSO for imaging of in vivo behavior of the individual isomers by positron emission tomography.

Ming-Rong Zhang, Kenji Furutsuka, N. Nengaki, 2011, Bioorganic & medicinal chemistry.

PET imaging of MRP1 function in the living brain: method development and future perspectives.

T. Irie, T. Okamura, T. Kikuchi, 2010, Current topics in medicinal chemistry.

PET probes for imaging brain acetylcholinesterase.

Ming-Rong Zhang, T. Irie, T. Okamura, 2013, Journal of labelled compounds & radiopharmaceuticals.

N-[18F]fluoroethylpiperidin-4-ylmethyl butyrate: a novel radiotracer for quantifying brain butyrylcholinesterase activity by positron emission tomography.

Ming-Rong Zhang, Kazutoshi Suzuki, K. Fukushi, 2004, Bioorganic & medicinal chemistry letters.

Kinetics and metabolism of apocynin in the mouse brain assessed with positron-emission tomography.

Ming-Rong Zhang, H. Wakizaka, Maki Okada, 2018, Phytomedicine : international journal of phytotherapy and phytopharmacology.

N-[18F] fluoroethylpiperidin-4ylmethyl acetate, a novel lipophilic acetylcholine analogue for PET measurement of brain acetylcholinesterase activity.

Ming-Rong Zhang, Kazutoshi Suzuki, K. Fukushi, 2005, Journal of medicinal chemistry.

Rapid ‘on-column’ preparation of hydrogen [11C]cyanide from [11C]methyl iodide via [11C]formaldehyde

Ming-Rong Zhang, A. Gee, Masanao Ogawa, 2022, Chemical science.

A novel noninvasive method for assessing glutathione-conjugate efflux systems in the brain.

K. Fukushi, T. Irie, Y. Arano, 2007, Bioorganic & medicinal chemistry.

11C-Labeled Radiotracer for Noninvasive and Quantitative Assessment of the Thiocyanate Efflux System in the Brain.

Ming-Rong Zhang, Satoshi Tsukamoto, N. Nengaki, 2022, Bioconjugate chemistry.

Effects of halogenation on tyrosine phosphorylation and peptide binding to the SRC homology 2 domain of lymphocyte-specific protein tyrosine kinase.

K. Fukushi, T. Irie, K. Odaka, 2012, Biological & pharmaceutical bulletin.

Cerebral acetylcholinesterase imaging: development of the radioprobes.

Ming-Rong Zhang, K. Fukushi, T. Irie, 2007, Current topics in medicinal chemistry.

In vivo evaluation of N‐[18F]fluoroethylpiperidin‐4ylmethyl acetate in rats compared with MP4A as a probe for measuring cerebral acetylcholinesterase activity

Ming-Rong Zhang, K. Fukushi, T. Irie, 2010, Synapse.

Acetate in Rats Compared With MP 4 A as a Probe for Measuring Cerebral Acetylcholinesterase Activity

Ming-Rong Zhang, K. Fukushi, T. Irie, 2009 .

Effect of radiolabeled metabolite elimination from the brain on the accuracy of cerebral enzyme activity estimation using positron emission tomography with substrate tracers

Tomoyuki Ohya, Yuji Nagai, Tatsuya Kikuchi, 2011, NeuroImage.

Use of a novel radiometric method to assess the inhibitory effect of donepezil on acetylcholinesterase activity in minimally diluted tissue samples

T. Obata, K. Fukushi, T. Irie, 2010, British journal of pharmacology.

Piperidine-4-methanthiol ester derivatives for a selective acetylcholinesterase assay.

K. Fukushi, T. Irie, T. Okamura, 2010, Biological & pharmaceutical bulletin.

In-vivo imaging of blood–brain barrier permeability using positron emission tomography with 2-amino-[3-11C]isobutyric acid

I. Aoki, Y. Ikoma, T. Kamakura, 2015, Nuclear medicine communications.

Benzyl [(11)C]Hippurate as an Agent for Measuring the Activities of Organic Anion Transporter 3 in the Brain and Multidrug Resistance-Associated Protein 4 in the Heart of Mice.

A. Gee, Joji Yui, T. Fukumura, 2016, Journal of medicinal chemistry.

Improvement of brain uptake for in vivo PET imaging of astrocytic oxidative metabolism using benzyl [1-(11)C]acetate.

O. Inoue, R. Nakao, H. Wakizaka, 2013, Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine.

Mechanisms of glutathione-conjugate efflux from the brain into blood: Involvement of multiple transporters in the course

H. Wakizaka, Maki Okada, T. Okamura, 2018, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.