K. M. Rahman

发表

Biaryl polyamides as a new class of DNA quadruplex-binding ligands.

S. Neidle, M. Gunaratnam, A. Reszka, 2009, Chemical communications.

The pyrrolobenzodiazepine dimer SJG-136 forms sequence-dependent intrastrand DNA cross-links and monoalkylated adducts in addition to interstrand cross-links.

A. Thompson, D. Thurston, C. James, 2009, Journal of the American Chemical Society.

Effect of base sequence on the DNA cross-linking properties of pyrrolobenzodiazepine (PBD) dimers

D. Thurston, C. James, K. M. Rahman, 2011, Nucleic acids research.

The minor groove-binding agent ELB-21 forms multiple interstrand and intrastrand covalent cross-links with duplex DNA and displays potent bactericidal activity against methicillin-resistant Staphylococcus aureus

J. Hinds, P. Taylor, D. Thurston, 2011, The Journal of antimicrobial chemotherapy.

Observation of the reversibility of a covalent pyrrolobenzodiazepine (PBD) DNA adduct by HPLC/MS and CD spectroscopy.

D. Thurston, C. James, K. M. Rahman, 2011, Organic & biomolecular chemistry.

DNA Sequence Preference and Adduct Orientation of Pyrrolo[2,1-c][1,4]benzodiazepine Antitumor Agents.

D. Thurston, C. James, K. M. Rahman, 2010, ACS medicinal chemistry letters.

Observation of unphosphorylated STAT3 core protein binding to target dsDNA by PEMSA and X‐ray crystallography

G. Parkinson, T. Bui, A. Drake, 2013, FEBS letters.

Adsorption of Poly(amidoamine) Dendrimers on Gold

N. Turro, D. Tomalia, C. Durning, 2000 .

Effect of microwave irradiation on covalent ligand-DNA interactions.

D. Thurston, K. M. Rahman, 2009, Chemical communications.

Observation of a dynamic equilibrium between DNA hairpin and duplex forms of covalent adducts of a minor groove binding agent.

P. Howard, D. Thurston, C. James, 2009, Chemical communications.

Methylene-linked bis-phenylbenzimidazoles - a new scaffold to target telomeric DNA/RNA hybrid duplex.

K. M. Rahman, Mohammad Kaisarul Islam, Paul J. M. Jackson, 2018, Organic & biomolecular chemistry.

DNA Sequence Preference and Adduct Orientation of Pyrrolo[2,1-c][1,4]benzodiazepine Antitumor Agents.

D. Thurston, C. James, K. M. Rahman, 2010, ACS medicinal chemistry letters.

The pyrrolobenzodiazepine dimer SJG-136 forms sequence-dependent intrastrand DNA cross-links and monoalkylated adducts in addition to interstrand cross-links.

A. Thompson, D. Thurston, C. James, 2009, Journal of the American Chemical Society.

GC-targeted C8-linked pyrrolobenzodiazepine-biaryl conjugates with femtomolar in vitro cytotoxicity and in vivo antitumor activity in mouse models.

P. Jackson, R. B. Pedley, J. Hartley, 2013, Journal of medicinal chemistry.