L. Atangan

发表

GIPR antagonist antibodies conjugated to GLP-1 peptide are bispecific molecules that decrease weight in obese mice and monkeys

J. Harrold, M. Stolina, Shu-Chen Lu, 2021, Cell reports. Medicine.

JPET # 157685 1 Long-term Inhibition of the Glucagon Receptor with a Monoclonal Antibody in Mice Causes Sustained Improvement in Glycemic Control , with Reversibility of Alpha-Cell Hyperplasia and Hyperglucagonemia

Katherine A. Winters, T. Boone, R. Lindberg, 2009 .

Long-Term Inhibition of the Glucagon Receptor with a Monoclonal Antibody in Mice Causes Sustained Improvement in Glycemic Control, with Reversible α-Cell Hyperplasia and Hyperglucagonemia

Katherine A. Winters, T. Boone, R. Lindberg, 2009, Journal of Pharmacology and Experimental Therapeutics.

An apoA-I mimetic peptibody generates HDL-like particles and increases alpha-1 HDL subfraction in mice[S]

Shu-Chen Lu, M. Véniant, W. Gu, 2012, Journal of Lipid Research.

Integrities of A/B and C domains of RXR are required for rexinoid-induced caspase activations and apoptosis

S. Qin, Geoffrey Brown, Yi Zhao, 2008, The Journal of Steroid Biochemistry and Molecular Biology.

Resveratrol is Not a Direct Activator of SIRT1 Enzyme Activity

Shu-Chen Lu, Minghan Wang, D. Beher, 2009, Chemical biology & drug design.

An antagonist of retinoic acid receptors more effectively inhibits growth of human prostate cancer cells than normal prostate epithelium

S. Qin, R. Chandraratna, Y. Zhao, 2004, British Journal of Cancer.

A retinoid-related molecule that does not bind to classical retinoid receptors potently induces apoptosis in human prostate cancer cells through rapid caspase activation.

S. Qin, Geoffrey Brown, Yi Zhao, 2004, Cancer research.

Strategy for the identification of GPR23/LPA4 receptor agonists and inverse agonists.

Shu-Chen Lu, W. Gu, Xiaoning Zhao, 2010, Assay and drug development technologies.

Casein Kinase 1α Interacts with Retinoid X Receptor and Interferes with Agonist-induced Apoptosis*

S. Qin, Geoffrey Brown, Yi Zhao, 2004, Journal of Biological Chemistry.

Anti-obesity effects of GIPR antagonists alone and in combination with GLP-1R agonists in preclinical models

D. Bates, C. Murawsky, Zhulun Wang, 2018, Science Translational Medicine.

Chronic glucose-dependent insulinotropic polypeptide receptor (GIPR) agonism desensitizes adipocyte GIPR activity mimicking functional GIPR antagonism

Yuan Cheng, M. Véniant, J. Falsey, 2020, Nature Communications.