Donna W. Lee

发表

Evaluation and use of an anti‐cynomolgus monkey CD79b surrogate antibody–drug conjugate to enable clinical development of polatuzumab vedotin

D. Danilenko, S. Prabhu, M. Go, 2019, British journal of pharmacology.

Pre‐clinical and translational pharmacology of a human interleukin‐22 IgG fusion protein for potential treatment of infectious or inflammatory diseases

D. Danilenko, W. Ouyang, L. Diehl, 2018, Biochemical pharmacology.

Antibody-Drug Conjugates Derived from Cytotoxic seco-CBI-Dimer Payloads Are Highly Efficacious in Xenograft Models and Form Protein Adducts In Vivo.

Jeffrey T. Lau, R. Rowntree, B. Vollmar, 2019, Bioconjugate chemistry.

Nonclinical safety assessment of a human interleukin‐22FC IG fusion protein demonstrates in vitro to in vivo and cross‐species translatability

D. Danilenko, W. Ouyang, B. Harder, 2018, Pharmacology research & perspectives.

Nonclinical Development of Multi-targeting Biopharmaceuticals

Wendy G. Halpern, Rodney A. Prell, Donna W. Lee, 2013 .

The use of recovery animals in nonclinical safety assessment studies with monoclonal antibodies: further 3Rs opportunities remain.

M. Leach, P. van Meer, L. de Haan, 2023, Regulatory toxicology and pharmacology : RTP.

Toxicologic Pathology Forum: Opinion on Not Euthanizing Control Animals in the Recovery Phase of Non-Rodent Toxicology Studies

Binod Jacob, Bhanu P. Singh, X. Palazzi, 2022, Toxicologic pathology.

An Anti–CD22-seco-CBI-Dimer Antibody–Drug Conjugate (ADC) for the Treatment of Non-Hodgkin Lymphoma That Provides a Longer Duration of Response than Auristatin-Based ADCs in Preclinical Models

R. Rowntree, P. Dragovich, Fiona Zhong, 2020, Molecular Cancer Therapeutics.

Re-evaluating the need for chronic toxicity studies with therapeutic monoclonal antibodies, using a weight of evidence approach.

M. Leach, P. van Meer, L. de Haan, 2022, Regulatory toxicology and pharmacology : RTP.

Multiplexed Quantitative Analysis of Antibody-Drug Conjugates with Labile CBI-Dimer Payloads In Vivo Using Immunoaffinity LC-MS/MS.

Suk-Joon Hyung, D. Leipold, Ola M. Saad, 2021, Analytical chemistry.

An IQ Consortium Perspective on The Scientific Committee on Health, Environmental and Emerging Risks Final Opinion on the Need for Nonhuman Primates in Biomedical Research, Production and Testing of Products and Devices (Update 2017)

M. Wright, R. Schulingkamp, Donna W. Lee, 2019, Toxicologic pathology.

Re-evaluating the need for chronic toxicity studies with therapeutic monoclonal antibodies, using a weight of evidence approach.

M. Leach, P. van Meer, L. de Haan, 2022, Regulatory toxicology and pharmacology : RTP.