T. Hosaka

发表

Isolation and structure determination of a new cytotoxic peptide, curacozole, from Streptomyces curacoi based on genome mining

H. Komaki, T. Oyoshi, S. Kodani, 2018, The Journal of Antibiotics.

Dramatic Activation of Antibiotic Production in Streptomyces coelicolor by Cumulative Drug Resistance Mutations

Guojun Wang, K. Ochi, Guojun Wang, 2008, Applied and Environmental Microbiology.

A possible mechanism for lincomycin induction of secondary metabolism in Streptomyces coelicolor A3(2)

K. Ochi, Y. Imai, T. Hosaka, 2018, Antonie van Leeuwenhoek.

Lincomycin at Subinhibitory Concentrations Potentiates Secondary Metabolite Production by Streptomyces spp

K. Ochi, S. Sato, Y. Imai, 2015 .

Lincomycin at Subinhibitory Concentrations Potentiates Secondary Metabolite Production by Streptomyces spp

K. Ochi, S. Sato, Y. Imai, 2015, Applied and Environmental Microbiology.

Development of the ability to produce secondary metabolites in Streptomyces through the acquisition of erythromycin resistance

K. Ochi, Y. Imai, T. Hosaka, 2012, The Journal of Antibiotics.

Rare earth elements activate the secondary metabolite–biosynthetic gene clusters in Streptomyces coelicolor A3(2)

K. Ochi, Yukinori Tanaka, T. Hosaka, 2010, The Journal of Antibiotics.

EshA Accentuates ppGpp Accumulation and Is Conditionally Required for Antibiotic Production in Streptomyces coelicolor A3(2)

M. Bibb, H. Aoki, K. Ochi, 2006, Journal of bacteriology.

Characterization of the NADH-linked acetylacetoin reductase/2,3-butanediol dehydrogenase gene from Bacillus cereus YUF-4.

T. Ohtsuki, T. Kudo, M. Ohkuma, 2001, Journal of bioscience and bioengineering.

Discovery of a new mechanism of 2,3-butanediol stereoisomer formation in Bacillus cereus YUF-4

S. Ui, A. Mimura, Kazuhide Watanabe, 1998 .

Purification and properties of acetylacetoin synthase from Bacillus sp. YUF-4.

S. Ui, A. Mimura, T. Hosaka, 1998, Bioscience, biotechnology, and biochemistry.

Separation and properties of two acetylacetoin reductases from Bacillus cereus YUF-4.

S. Ui, A. Mimura, T. Hosaka, 1999, Bioscience, biotechnology, and biochemistry.

Acetylacetoin synthase as a marker enzyme for detecting the 2,3-butanediol cycle.

T. Ohtsuki, S. Ui, A. Mimura, 2002, Journal of bioscience and bioengineering.

Enhanced Expression of S-Adenosylmethionine Synthetase Causes Overproduction of Actinorhodin in Streptomyces coelicolor A3(2)

A. Lezhava, K. Ochi, S. Okamoto, 2003, Journal of bacteriology.

Unique Physiological and Genetic Features of Ofloxacin-Resistant Streptomyces Mutants

H. Nakagawa, S. Kodani, Kanata Hoshino, 2021, Applied and environmental microbiology.

Lincomycin-Induced Secondary Metabolism in Streptomyces lividans 66 with a Mutation in the Gene Encoding the RNA Polymerase Beta Subunit

Momoko Kobayashi, T. Maruyama, Kanata Hoshino, 2020, Current Microbiology.

Improvement of α-Amylase Production by Modulation of Ribosomal Component Protein S12 in Bacillus subtilis 168

K. Ochi, K. Kurosawa, N. Tamehiro, 2006, Applied and Environmental Microbiology.

Antibacterial discovery in actinomycetes strains with mutations in RNA polymerase or ribosomal protein S12

Mitsuru Yoshida, Hideyuki Muramatsu, Yasuhisa Tsurumi, 2009, Nature Biotechnology.

Structural Basis for Transcription Regulation by Alarmone ppGpp

S. Yokoyama, V. Patlan, D. Vassylyev, 2004, Cell.

Ribosome engineering and secondary metabolite production.

K. Ochi, K. Kurosawa, Y. Tozawa, 2004, Advances in applied microbiology.

Innovative Approach for Improvement of an Antibiotic-Overproducing Industrial Strain of Streptomyces albus

Noboru Otake, K. Ochi, Haifeng Hu, 2003, Applied and Environmental Microbiology.

New strategies for drug discovery: activation of silent or weakly expressed microbial gene clusters

K. Ochi, Takeshi Hosaka, Kozo Ochi, 2012, Applied Microbiology and Biotechnology.

Effects of Escherichia coli ribosomal protein S12 mutations on cell-free protein synthesis.

T. Kigawa, S. Yokoyama, M. Shirouzu, 2004, European journal of biochemistry.

The novel mutation K87E in ribosomal protein S12 enhances protein synthesis activity during the late growth phase in Escherichia coli

S. Yokoyama, M. Shirouzu, K. Ochi, 2004, Molecular Genetics and Genomics.

An aberrant protein synthesis activity is linked with antibiotic overproduction in rpsL mutants of Streptomyces coelicolor A3(2).

K. Ochi, T. Hosaka, Y. Okamoto-Hosoya, 2003, Microbiology.

Mutations in rsmG, Encoding a 16S rRNA Methyltransferase, Result in Low-Level Streptomycin Resistance and Antibiotic Overproduction in Streptomyces coelicolor A3(2)

K. Ochi, S. Tokuyama, S. Okamoto, 2007, Journal of bacteriology.

A putative mechanism underlying secondary metabolite overproduction by Streptomyces strains with a 23S rRNA mutation conferring erythromycin resistance

K. Ochi, Y. Imai, Kanata Hoshino, 2020, Applied Microbiology and Biotechnology.

New strategies for drug discovery: activation of silent or weakly expressed microbial gene clusters

K. Ochi, T. Hosaka, 2012, Applied Microbiology and Biotechnology.

Isolation and structure determination of a new cytotoxic peptide, curacozole, from Streptomyces curacoi based on genome mining

H. Komaki, T. Oyoshi, S. Kodani, 2018, The Journal of Antibiotics.

Heterologous expression of a plant RelA-SpoT homologue results in increased stress tolerance in Saccharomyces cerevisiae by accumulation of the bacterial alarmone ppGpp.

Y. Ozeki, K. Ochi, S. Okamoto, 2012, Microbiology.

Increased expression of ribosome recycling factor is responsible for the enhanced protein synthesis during the late growth phase in an antibiotic‐overproducing Streptomyces coelicolor ribosomal rpsL mutant

K. Ochi, Takeshi Hosaka, Jun Xu, 2006, Molecular microbiology.

Physiological Analysis of the Stringent Response Elicited in an Extreme Thermophilic Bacterium, Thermus thermophilus

H. Aoki, K. Ochi, Kosaku Takahashi, 2006, Journal of bacteriology.

Combined Drug Resistance Mutations Substantially Enhance Enzyme Production in Paenibacillus agaridevorans

Yuh Shiwa, H. Yoshikawa, Ken Kasahara, 2018, Journal of bacteriology.