D. Hoyt

发表

Sensitivity of mice to lipopolysaccharide is increased by a high saturated fat and cholesterol diet

Tongzheng Liu, Hong Huang, J. Rose, 2007, Journal of Inflammation.

Src-mediated Post-translational Regulation of Endoglin Stability and Function Is Critical for Angiogenesis*

Sanjay Kumar, K. Mythreye, L. Hawinkels, 2014, The Journal of Biological Chemistry.

The neutral cysteine protease bleomycin hydrolase is essential for epidermal integrity and bleomycin resistance.

G. Homanics, J. Lazo, E. Klein, 1999, Proceedings of the National Academy of Sciences of the United States of America.

A Specific Picomolar Hybridization-Based ELISA Assay for the Determination of Phosphorothioate Oligonucleotides in Plasma and Cellular Matrices

G. Marcucci, Kenneth K. Chan, W. Blum, 2006, Pharmaceutical Research.

Endoglin Regulation of Smad2 Function Mediates Beclin1 Expression and Endothelial Autophagy*

Sanjay Kumar, K. Mythreye, L. Hawinkels, 2015, The Journal of Biological Chemistry.

Integrins inhibit LPS-induced DNA strand breakage in cultured lung endothelial cells.

Simon C Watkins, R. Mannix, J. Lazo, 1996, The American journal of physiology.

Collagen is a survival factor against LPS-induced apoptosis in cultured sheep pulmonary artery endothelial cells.

R. Mannix, J. Lazo, B. Pitt, 1995, The American journal of physiology.

An efficient, nonenzymatic method for isolation and culture of murine aortic endothelial cells and their response to inflammatory stimuli

Hong Huang, D. Hoyt, J. Mcintosh, 2003, In Vitro Cellular & Developmental Biology - Animal.

Bleomycin: a pharmacologic tool in the study of the pathogenesis of interstitial pulmonary fibrosis.

J. Lazo, S. Sebti, B. Pitt, 1990, Pharmacology & therapeutics.

Regulation of bleomycin-induced DNA breakage and chromatin structure in lung endothelial cells by integrins and poly(ADP-ribose) polymerase.

Andrea Michele Graytock, H. Huang, Hong Huang, 2001, Molecular pharmacology.

Cellular Uptake and Intracellular Levels of the Bcl-2 Antisense G 3139 in Cultured Cells and Treated Patientswith AcuteMyeloid Leukemia

M. Caligiuri, M. Grever, J. Byrd, 2005 .

Alterations in pulmonary mRNA encoding procollagens, fibronectin and transforming growth factor-beta precede bleomycin-induced pulmonary fibrosis in mice.

J. Lazo, D. Hoyt, 1988, The Journal of pharmacology and experimental therapeutics.

CHAPTER 15 – THE USE OF BLEOMYCIN IN MODEL SYSTEMS TO STUDY THE PATHOGENESIS OF INTERSTITIAL PULMONARY FIBROSIS

J. Lazo, B. Pitt, D. Hoyt, 1993 .

Antibody-directed coupling of endoglin and MMP-14 is a key mechanism for endoglin shedding and deregulation of TGF-β signaling

S. Kumar, A. Nixon, C. Theuer, 2013, Oncogene.

Murine strain differences in acute lung injury and activation of poly(ADP-ribose) polymerase by in vitro exposure of lung slices to bleomycin.

J. Lazo, D. Hoyt, 1992, American journal of respiratory cell and molecular biology.

NAD depletion after in vitro exposure of murine lung slices to bleomycin.

J. Lazo, D. Hoyt, 1993, Biochemical pharmacology.

Integrin activation protects pulmonary endothelial cells from the genotoxic effects of bleomycin.

J. Lazo, M. Gerritsen, B. Pitt, 1997, The American journal of physiology.

Acute pneumocyte injury, poly(ADP-ribose) polymerase activity, and pyridine nucleotide levels after in vitro exposure of murine lung slices to cyclophosphamide.

J. Lazo, D. Hoyt, 1994, Biochemical pharmacology.

Angiostatic actions of capsicodendrin through selective inhibition of VEGFR2-mediated AKT signaling and disregulated autophagy

Sanjay Kumar, C. Beattie, L. Rakotondraibe, 2016, Oncotarget.

Novel phenanthridinone inhibitors of poly(adenosine 5′-diphosphate-ribose) synthetase: Potent cytoprotective and antishock agents*

F. Gallyas, E. Baloglu, É. Szabó, 2002, Critical care medicine.

Diabetic endothelial dysfunction: the role of poly(ADP-ribose) polymerase activation

K. Murthy, É. Szabó, C. Szabó, 2001, Nature Medicine.

Peptidylprolyl cis/trans isomerase, NIMA-interacting 1 (PIN1) regulates pulmonary effects of endotoxin and tumor necrosis factor-α in mice.

N. Lee, Tongzheng Liu, D. Hoyt, 2014, Biochemical and biophysical research communications.

Nitric oxide inhibits lipopolysaccharide-induced apoptosis in pulmonary artery endothelial cells.

Simon C Watkins, T. Billiar, J. Engelhardt, 1998, American journal of physiology. Lung cellular and molecular physiology.

The small molecule curcumin analog FLLL32 induces apoptosis in melanoma cells via STAT3 inhibition and retains the cellular response to cytokines with anti-tumor activity

G. Lesinski, Jiayuh Lin, D. Benson, 2010, Molecular Cancer.

A novel small molecule inhibits STAT3 phosphorylation and DNA binding activity and exhibits potent growth suppressive activity in human cancer cells

Li Lin, G. Lesinski, Jiayuh Lin, 2010, Molecular Cancer.

Nitric oxide inhibits lipopolysaccharide-induced apoptosis in pulmonary artery endothelial cells.

Simon C Watkins, T. Billiar, J. Engelhardt, 1998, The American journal of physiology.

Early increases in pulmonary mRNA encoding procollagens and transforming growth factor-beta in mice sensitive to cyclophosphamide-induced pulmonary fibrosis.

J. Lazo, D. Hoyt, 1989, The Journal of pharmacology and experimental therapeutics.

Protein Never in Mitosis Gene A Interacting-1 regulates calpain activity and the degradation of cyclooxygenase-2 in endothelial cells

Yongcheng Huang, Vaibhav B. Shah, L. Keshvara, 2009, Journal of Inflammation.

Enhanced apoptosis in metallothionein null cells.

J. Lazo, B. Pitt, Y. Kondo, 1997, Molecular pharmacology.

Vascular endothelial toxicity induced by HIV protease inhibitor

R. Baliga, J. Bauer, Cynthia Liu, 2007, Cardiovascular Toxicology.

The molecular basis of interstitial pulmonary fibrosis caused by antineoplastic agents.

J. Lazo, D. Hoyt, 1990, Cancer treatment reviews.

Integrin activation suppresses etoposide-induced DNA strand breakage in cultured murine tumor-derived endothelial cells.

R. Mannix, J. Lazo, R. Modzelewski, 1996, Cancer research.

Cellular Uptake and Intracellular Levels of the Bcl-2 Antisense G3139 in Cultured Cells and Treated Patients with Acute Myeloid Leukemia

M. Caligiuri, M. Grever, J. Byrd, 2005, Clinical Cancer Research.

p38 Mitogen-Activated Protein Kinase Mediates Synergistic Induction of Inducible Nitric-Oxide Synthase by Lipopolysaccharide and Interferon-γ through Signal Transducer and Activator of Transcription 1 Ser727 Phosphorylation in Murine Aortic Endothelial Cells

Hong Huang, J. Rose, D. Hoyt, 2004 .

p38 Mitogen-activated protein kinase mediates synergistic induction of inducible nitric-oxide synthase by lipopolysaccharide and interferon-gamma through signal transducer and activator of transcription 1 Ser727 phosphorylation in murine aortic endothelial cells.

Hong Huang, J. Rose, D. Hoyt, 2004, Molecular pharmacology.

Effects of angiotensin II on vascular endothelial cells: formation of receptor-mediated reactive nitrogen species.

J. Bauer, S. Wattanapitayakul, D. Hoyt, 2003, Biochemical pharmacology.

A novel small molecule inhibits STAT 3 phosphorylation and DNA binding activity and exhibits potent growth suppressive activity in human cancer cells

Li Lin, G. Lesinski, Jiayuh Lin, 2010 .

Genesis of discrete higher order DNA fragments in apoptotic human prostatic carcinoma cells.

J. Lazo, T. Calmels, J. Yalowich, 1996, Molecular pharmacology.

Nucleophilic distribution of metallothionein in human tumor cells.

Simon C Watkins, J. Lazo, E. S. Woo, 1996, Experimental Cell Research.

Integrin Engagement Increases Histone H3 Acetylation and Reduces Histone H1 Association with DNA in Murine Lung Endothelial Cells

Hong Huang, J. Rose, D. Hoyt, 2005, Molecular Pharmacology.

Calpastatin is regulated by protein never in mitosis gene A interacting-1 (PIN1) in endothelial cells.

Tongzheng Liu, D. Hoyt, Ryan A. Schneider, 2011, Biochemical and biophysical research communications.

Protein Never in Mitosis Gene A Interacting-1 (PIN1) regulates degradation of inducible nitric oxide synthase in endothelial cells.

Yongcheng Huang, L. Keshvara, Tongzheng Liu, 2008, American journal of physiology. Cell physiology.

Acute pulmonary toxicity of bleomycin: DNA scission and matrix protein mRNA levels in bleomycin-sensitive and -resistant strains of mice.

J. Lazo, J. Harrison, D. Hoyt, 1989, Molecular pharmacology.

Base Excision Repair Proteins Are Required for Integrin-Mediated Suppression of Bleomycin-Induced DNA Breakage in Murine Lung Endothelial Cells

J. Rose, D. Hoyt, Rostislav I. Likhotvorik, 2007, Journal of Pharmacology and Experimental Therapeutics.

Characterization of cholestasis induced by 1,3-bis-(2-chloroethyl)-1-nitrosourea in rats

D. Hoyt, 1984 .

Journal of Inflammation Sensitivity of Mice to Lipopolysaccharide Is Increased by a High Saturated Fat and Cholesterol Diet

Tongzheng Liu, Hong Huang, Rachel L. Stevens, 2022 .

The small molecule curcumin analog FLLL32 induces apoptosis in melanoma cells via STAT3 inhibition and retains the cellular response to cytokines with anti-tumor activity

G. Lesinski, Jiayuh Lin, W. Carson, 2010 .

The small molecule curcumin analog FLLL32 induces apoptosis in melanoma cells via STAT3 inhibition and retains the cellular response to cytokines with anti-tumor activity

G. Lesinski, Jiayuh Lin, D. Benson, 2010 .

Integrin-mediated suppression of endotoxin-induced DNA damage in lung endothelial cells is sensitive to poly(ADP-ribose) polymerase-1 gene deletion.

C. Szabó, Hong Huang, D. Hoyt, 2003, International journal of molecular medicine.