J. Roberts

发表

Isolation, crystallization, and properties of Achromobacteraceae glutaminase-asparaginase with antitumor activity.

W. Dolowy, J. Holcenberg, J. Roberts, 1972, The Journal of biological chemistry.

Ion binding induces closed conformation in Pseudomonas 7A glutaminase-asparaginase (PGA): crystal structure of the PGA-SO4(2-)-NH4+ complex at 1.7 A resolution.

L. Lebioda, C. Jakob, K. Lewiński, 1997, Biochemistry.

[13N]Ammonia and L-[amide-13N]glutamine metabolism in glutaminase-sensitive and glutaminase-resistant murine tumors.

K. Rosenspire, A. Gelbard, A. Cooper, 1985, Biochimica et biophysica acta.

Purification andcharacterization oftheMsplDNA methyltransferas e cloned andoverexpressed inE.coli

J. Roberts, 1992 .

Loss of fimbrial adhesion with the addition of Vaccinum macrocarpon to the growth medium of P-fimbriated Escherichia coli.

J. Roberts, B. Kaack, J. Roberts, 1998, The Journal of urology.

Glutaminase (PEG-PGA) increases antitumoral efficacy of cytotoxic agents.

J. Drevs, C. Unger, R. Harzmann, 2004, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Cell cycle phase perturbations by 6-diazo-5-oxo-L-norleucine and acivicin in normal and neoplastic human cell lines.

K. R. Huber, D. F. Mitchell, J. Roberts, 1987, British Journal of Cancer.

Structures of amidohydrolases. Amino acid sequence of a glutaminase-asparaginase from Acinetobacter glutaminasificans and preliminary crystallographic data for an asparaginase from Erwinia chrysanthemi.

A. Wlodawer, E. Appella, I. Weber, 1988, The Journal of biological chemistry.

Characterization of crystals of L-glutaminase-asparaginase from Acinetobacter glutaminasificans and Pseudomonas 7A.

A. Wlodawer, J. Holcenberg, J. Roberts, 1977, Journal of molecular biology.

Enhancement of antitumor activity of glutamine antagonists 6-diazo-5-oxo-L-norleucine and acivicin in cell culture by glutaminase-asparaginase.

H. Rosenfeld, J. Roberts, 1981, Cancer research.

Purification and properties of a highly potent antitumor glutaminase-asparaginase from Pseudomonas 7Z.

J. Roberts, 1976, The Journal of biological chemistry.

Isolation, crystallization, and properties of indolyl-3-alkane alpha-hydroxylase. A novel tryptophan-metabolizing enzyme.

H. Rosenfeld, J. Roberts, 1977, The Journal of biological chemistry.

Therapeutic properties of a new glutaminase-asparaginase preparation and the influence of the lactate dehydrogenase-elevating virus.

W. Dolowy, J. Holcenberg, D. Spackman, 1974, Cancer research.

Biologic and antineoplastic effects of enzyme-mediated in vivo depletion of L-glutamine, L-tryptophan, and L-histidine.

H. Rosenfeld, J. Roberts, F. Schmid, 1979, Cancer treatment reports.

Metabolism of nephrotoxic isopropylcyclohexane in male Fischer 344 rats.

G. Henningsen, J. Roberts, K. Yu, 1988, Journal of toxicology and environmental health.

The metabolism of t-butylcyclohexane in Fischer-344 male rats with hyaline droplet nephropathy.

G. Henningsen, J. Roberts, K. Yu, 1987, Toxicology letters.

Amino acid sequence of the diazooxonorleucine binding site of Acinetobacter and Pseudomonas 7A glutaminase--asparaginase enzymes.

J. Holcenberg, J Roberts, J S Holcenberg, 1978, Biochemistry.

Inhibition of mouse retroviral disease by bioactive glutaminase-asparaginase.

W. Mcgregor, J Roberts, W G McGregor, 1991, The Journal of general virology.

Phase I evaluation of succinylated Acinetobacter glutaminase-asparaginase in adults.

R. Warrell, T. Chou, S. Sternberg, 1980, Cancer research.

Kinetics of uptake and activity in mouse liver of glutaminase coupled to desialated orosomucoid.

J. Holcenberg, J. Roberts, G. Schmer, 1978, Biochimica et biophysica acta.

The antitumor activity of Escherichia coli L-asparaginase.

M. Prager, J. Roberts, N. Bachynsky, 1966, Cancer research.

Arginine decarboxylase from a Pseudomonas species

H. Rosenfeld, J. Roberts, 1976, Journal of bacteriology.

Response to highly purified L-asparaginase during therapy of acute leukemia.

A. Khan, N. Hill, J. Roberts, 1969, Cancer research.

Properties of a novel periplasmic catalase-peroxidase from Escherichia coli O157:H7.

D. Goodwin, Robert J. Thomas, J. Roberts, 2004, Archives of biochemistry and biophysics.

New Procedures for Purification of l-Asparaginase with High Yield from Escherichia coli

J. Roberts, J. Hill, G. Burson, 1968, Journal of bacteriology.

Preliminary crystal structure of Acinetobacter glutaminasificans glutaminase-asparaginase.

A Wlodawer, G L Gilliland, A. Wlodawer, 1994, The Journal of biological chemistry.

Antineoplastic and toxic effects of Acinetobacter and Pseudomonas glutaminase-asparaginases.

J. Roberts, F. Schmid, 1974, Cancer chemotherapy reports.

Cytotoxic effects of methionine alkyl esters and amides in normal and neoplastic cell lines.

J. Chapman, J. Roberts, M. Clement, 1989, Journal of pharmaceutical sciences.

Glutaminase induced prolonged regression of established Ehrlich carcinoma.

W. Dolowy, J. Holcenberg, J. Roberts, 1971, Life sciences. Pt. 2: Biochemistry, general and molecular biology.

The metabolism of ethylcyclohexane in Fischer 344 rats

D. Mattie, Kyung O. Yu, M. Parnell, 1990 .

Clinical evaluation of succinylated Acinetobacter glutaminase-asparaginase in adult leukemia.

R. Warrell, T. Chou, Z. Arlin, 1982, Cancer treatment reports.

The metabolism of 2, 5-dimethylhexane in male Fischer 344 rats

David R Mattie, D. Mattie, D. Bombick, 1991 .

Results from a phase I dose escalation study of PEGylated glutaminase in combination with 6-diazo-5-oxo-L-norleucine (DON) in advanced malignant solid tumors.

C. Unger, S. Al-Batran, E. Jäger, 2016, Journal of Clinical Oncology.

Stereochemistry and mechanism of reactions catalyzed by indolyl-3-alkane alpha-hydroxylase.

M. Tsai, H. Floss, H. Rosenfeld, 1979, The Journal of biological chemistry.

N-methyl-N-nitrosourea-induced transformation of rat urothelial cells in vitro is not mediated by activation of ras oncogenes.

M. Knowles, A. Proctor, R. Padua, 1987, Oncogene.

Kinetic properties and inhibition of Acinetobacter glutaminase-asparaginase.

T. Chou, T C Chou, J Roberts, 1983, Biochemical pharmacology.

The molecular symmetry of glutaminase‐asparaginases: rotation function studies of the Pseudomonas 7A and Acinetobacter enzymes

A. Wlodawer, H. Ammon, K. Murphy, 1983 .

The in vivo effects of leucine dehydrogenase from Bacillus sphaericus

J. Roberts, F. Schmid, K. Takai, 1974, FEBS letters.