I. Kovach

发表

NMR evidence for a short, strong hydrogen bond at the active site of a cholinesterase.

T. Harris, M. Massiah, A. Mildvan, 2000, Biochemistry.

Short, strong hydrogen bonds at the active site of human acetylcholinesterase: proton NMR studies.

M. Massiah, A. Mildvan, T. Rosenberry, 2001, Biochemistry.

Janus Emulsions from a One-Step Process; Optical Microscopy Images

J. Koetz, S. Friberg, H. Hasinovic, 2014 .

Modulation of human α-thrombin activity with phosphonate ester inhibitors

E. J. Enyedy, I. Kovach, 1997 .

Equilibrium topology and partial inversion of Janus drops: a numerical analysis.

J. Koetz, S. Friberg, I. Kovach, 2013, Chemphyschem : a European journal of chemical physics and physical chemistry.

Reaction progress at the transition state for nucleophilic attack on esters

R. Schowen, I. Kovach, J. Elrod, 1980 .

Completely engulfed olive/silicone oil Janus emulsions with gelatin and chitosan

J. Koetz, S. Friberg, J. Won, 2016, Colloid and Polymer Science.

Reversible modification of tissue-type plasminogen activator by methylphosphonate esters.

I. Kovach, O. Zhao, 1996, Bioorganic & medicinal chemistry.

Active-Site-Dependent Elimination of 4-Nitrophenol from 4-Nitrophenyl Alkylphosphonyl Serine Protease Adducts

E. J. Enyedy, I. Kovach, 1998 .

Reversible modulation of human factor Xa activity with phosphonate esters: media effects.

E. J. Enyedy, I. Kovach, 2000, Bioorganic & Medicinal Chemistry.

Janus emulsion mediated porous scaffold bio-fabrication.

Jens Rumschöttel, J. Koetz, S. Friberg, 2016, Colloids and surfaces. B, Biointerfaces.

Locating the rate-determining step(s) for three-step hydrolase-catalyzed reactions with DYNAFIT.

Daoning Zhang, J. Sheehy, I. Kovach, 2008, Biochimica et biophysica acta.

Alternate Pathways for Acetic Acid and Acetate ion Release from Acetylcholinesterase: a Molecular Dynamics Study

B. Brooks, I. Enyedy, I. Kovach, 1998 .

Alternate Pathways for Acetic Acid and Acetate Ion Release from Acetylcholinesterase

I. Enyedy, I. Kovach, 1998 .

Proton bridging in the interactions of thrombin with small inhibitors.

F. Jordan, A. Baykal, I. Kovach, 2009, Biochemistry.

Proton Bridging in Catalysis by and Inhibition of Serine Proteases of the Blood Cascade System

I. Kovach, 2021, Life.

Small molecular products of dealkylation in soman-inhibited electric eel acetylcholinesterase.

L. Pannell, C. Viragh, I. Kovach, 1999, Biochemistry.

Synthesis of chiral 4-nitrophenyl alkyl methylphosphonothioates: BF3·Et2O-catalyzed alcoholysis of phosphonamidothioates

I. Kovach, P. M. Reddy, 2002 .

Rate-determining carbonyl hydration in the intramolecular hydrolysis of phenacyl phosphonate esters : isotopic probes and activation parameters

Qinjian Zhao, I. Kovach, M. Keane, 1993 .

Measurement of acid-base equilibrium constants in acetonitrile/18-crown-6 solutions

I. Kovach, 1983 .

Catalytic recruitment in the inactivation of acetylcholinesterase by soman: temperature dependence of the solvent isotope effect

R. Schowen, I. Kovach, J. Huber, 1988 .

Proton bridging in the interactions of thrombin with hirudin and its mimics.

Daoning Zhang, F. Jordan, I. Kovach, 2013, Biochemistry.

Amino Acid Esters of Phenols as Prodrugs: Synthesis and Stability of Glycine, β-Aspartic acid, and α-Aspartic Acid Esters of p-Acetamidophenol

T. Higuchi, I. Kovach, I. H. Pitman, 1981 .

Nucleophilic and protolytic catalysis of phosphonate hydrolysis : isotope effects and activation parameters

Qinjian Zhao, A. J. Bennet, Jeffrey A. Bibbs, 1993 .

Transition-state structures for ester aminolysis with and without rate-limiting proton transfer

R. Schowen, M. Belz, I. Kovach, 1985 .

One-proton catalysis in the deacetylation of acetylcholinesterase

R. Schowen, I. Kovach, M. Larson, 1986 .

Identification of amino acid residues involved in the binding of Huperzine A to cholinesterases

P. Taylor, B. P. Doctor, Y. Pang, 1994, Protein science : a publication of the Protein Society.

Structure and dynamics of serine hydrolase-organophosphate adducts.

I. Kovach, 1988, Journal of enzyme inhibition.

Molecular dynamics study of active-site interactions with tetracoordinate transients in acetylcholinesterase and its mutants.

I. Enyedy, Á. Bencsura, I. Kovach, 2001, The Biochemical journal.

The Push-Pull Mechanism of Dealkylation in Soman-Inhibited Cholinesterases and Their Mutants

I. Kovach, 1998 .

Origins and diversity of the aging reaction in phosphonate adducts of serine hydrolase enzymes: what characteristics of the active site do they probe?

I. Enyedy, Á. Bencsura, I. Kovach, 1995, Biochemistry.

Phosphonate Ester Active Site Probes of Acetylcholinesterase, Trypsin and Chymotrypsin

I. Enyedy, Á. Bencsura, C. Viragh, 1995 .

Comparative study of the charge distribution in tetravalent carbonyl transients and organophosphorus adducts of trypsin

I. Kovach, D. Huhta, 1991 .

Kinetic isotope-effect probes of transition-state structure. Vibrational analysis of model transition states for carbonyl addition

R. Schowen, J. Rodgers, J. Hogg, 1980 .

β‐Secondary deuterium isotope effect and solvent isotope effects in catalysis by subtilisin BPN′

R. Schowen, I. Kovach, S. Do, 1990 .

Transition states of some acyl transfer reactions in acetonitrile 1

I. Kovach, 1980 .

Competitive irreversible inhibition of enzymes in the presence of a substrate: scope and limitations.

I. Kovach, 1991, Journal of enzyme inhibition.

Catalytic recruitment by phosphonyl derivatives as inactivators of acetylcholinesterase and substrates for imidazole-catalyzed hydrolysis: .beta.-deuterium isotope effects

A. J. Bennet, Jeffrey A. Bibbs, I. Kovach, 1989 .

Rate-limiting phosphorus-oxygen fission in the self-stimulated inactivation of acetylcholinesterase by 4-nitrophenyl 2-propyl methylphosphonate

R. Schowen, A. J. Bennet, I. Kovach, 1988 .

Efficient product clearance through exit channels in substrate hydrolysis by acetylcholinesterase

I M Kovach, N Qian, A Bencsura, 1994, FEBS letters.

Solution Dynamics of Phosphonate Ester Hydrolysis

I. Kovach, 1993 .

Reversible modulation of serine protease activity by phosphonate esters

I. Kovach, L. Mckay, 1992 .

Active site interactions in hydrated trypsin-organophosphate adducts: a yeti molecular mechanics study

I. Kovach, D. Huhta, S. Baptist, 1991 .

Comparative Study of Nucleophilic am) Enzymic Reactions of 2-Propyl Methylphosphonate Derivatives

A. J. Bennet, I. Kovach, 1990 .

Key active site residues in the inhibition of acetylcholinesterases by soman

I. Kovach, Ildiko M. Kovach, Naifeng Qian, 1993, FEBS letters.

Serine hydrolase-phosphyl ester interactions: Molecular modeling

I. Kovach, 1988 .

Short, strong hydrogen bonds on enzymes: NMR and mechanistic studies

G. T. Marks, T. Harris, M. Massiah, 2002 .

Deuterium solvent isotope effect and proton-inventory studies of factor Xa-catalyzed reactions.

Daoning Zhang, I. Kovach, 2006, Biochemistry.

Probing the Active Site of Acetylcholinesterase by Molecular Dynamics of Its Phosphonate Ester Adducts

I. Enyedy, Á. Bencsura, I. Kovach, 1996 .

pH Dependence of Dealkylation in Soman-Inhibited Cholinesterases and Their Mutants

B. P. Doctor, O. Lockridge, A. Saxena, 1998 .

Synthesis of Phenyl or 4-Nitrophenyl Methyl β-Ketophosphonate Esters

C. Viragh, I. Kovach, P. M. Reddy, 2002 .

The Deviant ATP-binding Site of the Multidrug Efflux Pump Pdr5 Plays an Active Role in the Transport Cycle*

S. Ambudkar, C. Furman, J. Mehla, 2013, The Journal of Biological Chemistry.

Stereochemistry and secondary reactions in the irreversible inhibition of serine hydrolases by organophosphorus compounds

I. Kovach, 2004 .

The pH dependence of dealkylation in soman-inhibited cholinesterases and their mutants: further evidence for a push-pull mechanism.

B. P. Doctor, O. Lockridge, A. Saxena, 1998, Biochemistry.

Unique push-pull mechanism of dealkylation in soman-inhibited cholinesterases.

C. Broomfield, C. Viragh, I. Kovach, 1997, Biochemistry.

A self-consistent mechanism for dealkylation in soman-inhibited acetylcholinesterase.

I. Enyedy, C. Viragh, I. Kovach, 1997, The Biochemical journal.