U. Galli

发表

Aryl azides as forgotten electrophiles in the Van Leusen reaction: a multicomponent transformation affording 4-tosyl-1-arylimidazoles.

E. Novellino, F. Meneghetti, G. Tron, 2019, The Journal of organic chemistry.

Identification of a sirtuin 3 inhibitor that displays selectivity over sirtuin 1 and 2.

P. Canonico, G. Tron, G. Sorba, 2012, European journal of medicinal chemistry.

Reciprocal Potentiation of the Antitumoral Activities of FK866, an Inhibitor of Nicotinamide Phosphoribosyltransferase, and Etoposide or Cisplatin in Neuroblastoma Cells

P. Canonico, N. Kaludercic, F. Di Lisa, 2011, Journal of Pharmacology and Experimental Therapeutics.

Replacement of the lactone moiety on podophyllotoxin and steganacin analogues with a 1,5-disubstituted 1,2,3-triazole via ruthenium-catalyzed click chemistry.

P. Canonico, G. Tron, G. Sorba, 2007, Bioorganic & medicinal chemistry.

Nicotinamide Phosphoribosyltransferase Acts as a Metabolic Gate for Mobilization of Myeloid-Derived Suppressor Cells.

A. Sica, M. Colombo, L. Rimassa, 2019, Cancer research.

Synthesis and Biological Evaluation of Isosteric Analogues of FK866, an Inhibitor of NAD Salvage

P. Canonico, R. Billington, G. Tron, 2008, ChemMedChem.

Design, synthesis, and biological evaluation of new (2E,6E)-10-(dimethylamino)-3,7-dimethyl-2,6-decadien-1-ol ethers as inhibitors of human and Trypanosoma cruzi oxidosqualene cyclase.

S. Oliaro-Bosso, F. Viola, G. Tron, 2007, Bioorganic & medicinal chemistry letters.

Biochemical and structural analysis of a cytosolic sulfotransferase of the malaria vector Anopheles gambiae overexpressed in the reproductive tissues

R. Miggiano, F. Rossi, M. Rizzi, 2022, Current research in structural biology.

Characterization of NAD Uptake in Mammalian Cells*

P. Canonico, R. Billington, F. Condorelli, 2008, Journal of Biological Chemistry.

Identification of potent triazolylpyridine nicotinamide phosphoribosyltransferase (NAMPT) inhibitors bearing a 1,2,3-triazole tail group.

E. Scanziani, G. Tron, S. Terrazzino, 2019, European journal of medicinal chemistry.

A nicotinamide phosphoribosyltransferase–GAPDH interaction sustains the stress-induced NMN/NAD+ salvage pathway in the nucleus

C. Angeletti, E. Aronica, J. Wohlschlegel, 2020, The Journal of Biological Chemistry.

Identification of Novel Triazole-Based Nicotinamide Phosphoribosyltransferase (NAMPT) Inhibitors Endowed with Antiproliferative and Antiinflammatory Activity.

S. Cuzzocrea, R. Di Paola, P. Canonico, 2017, Journal of medicinal chemistry.

Nicotinamide phosphoribosyltransferase (NAMPT) is over‐expressed in melanoma lesions

P. Ostano, A. Caldarelli, G. Chiorino, 2013, Pigment cell & melanoma research.

Identification of a novel NAMPT inhibitor by combinatorial click chemistry and chemical refinement

A. Caldarelli, A. Massarotti, G. Tron, 2015 .

Synthesis and antimalarial activities of some furoxan sulfones and related furazans.

S. Parapini, D. Taramelli, L. Lazzarato, 2005, European journal of medicinal chemistry.

The Guareschi Pyridine Scaffold as a Valuable Platform for the Identification of Selective PI3K Inhibitors

E. Hirsch, E. Ciraolo, A. Massarotti, 2015, Molecules.

Reaction between (Z)-arylchlorooximes and α-isocyanoacetamides: a procedure for the synthesis of aryl-α-ketoamide amides.

E. Novellino, S. Di Maro, G. Tron, 2014, The Journal of organic chemistry.

Water soluble furoxan derivatives as NO prodrugs.

C. Cena, R. Fruttero, A. Gasco, 1997, Journal of medicinal chemistry.

Unsymmetrically substituted furoxans. Part 16 . Reaction of benzenesulfonyl substituted furoxans with ethanol and ethanethiol in basic medium

R. Fruttero, A. Gasco, G. Ermondi, 1996 .

A fast route for the synthesis of tetrazolyl oximes by a novel multicomponent reaction between Z-chlorooximes, isocyanides and trimethylsilyl azide

E. Novellino, Michele Pavone, B. Pagano, 2017 .

The metabolic fate of the isocyanide moiety. Are isocyanides pharmacophore groups neglected by medicinal chemists?

G. Tron, S. Aprile, G. Grosa, 2020, Chemical research in toxicology.

Exploiting the Nucleophilicity of the Nitrogen Atom of Imidazoles: One-Pot Three-Component Synthesis of Imidazo-Pyrazines

E. Novellino, F. Meneghetti, G. Tron, 2019, Molecules.

A New Furoxan NO‐Donor Rabeprazole Derivative and Related Compounds

G. Coruzzi, M. Adami, C. Cena, 2003, Chembiochem : a European journal of chemical biology.

Synthesis and anti‐Helicobacter pylori properties of NO‐donor/metronidazole hybrids and related compounds

M. Bertinaria, R. Fruttero, A. Gasco, 2003 .

Recent Advances in NAMPT Inhibitors: A Novel Immunotherapic Strategy

G. Tron, A. Genazzani, G. Colombo, 2020, Frontiers in Pharmacology.

Drug Discovery for Soft Drugs on TRPV1 and TRPM8 Channels Using the Passerini Reaction.

G. Tron, T. Pirali, A. Genazzani, 2019, Methods in molecular biology.

Design, synthesis, and biological evaluation of combretabenzodiazepines: a novel class of anti-tubulin agents.

P. Canonico, A. Massarotti, G. Tron, 2015, Journal of medicinal chemistry.

Study of Anopheles gambiae 3-hydroxykynurenine transaminase activity and inhibition by LC-MS/MS method.

R. Miggiano, F. Rossi, M. Rizzi, 2019, Journal of pharmaceutical and biomedical analysis.

A Successful Replacement of Phenols with Isocyanides in the Bargellini Reaction: Synthesis of 3-Carboxamido-Isobutyric Acids.

E. Novellino, G. Tron, M. Giustiniano, 2016, The Journal of organic chemistry.

A novel potent nicotinamide phosphoribosyltransferase inhibitor synthesized via click chemistry.

Giuseppe Bifulco, Maria Giovanna Chini, Giovanni Sorba, 2010, Journal of medicinal chemistry.

Gene polymorphisms and risk of acute renal graft rejection: A field synopsis of meta-analyses and genome-wide association studies.

S. Terrazzino, S. Cargnin, J. Shin, 2020, Transplantation reviews.

Medicinal chemistry of nicotinamide phosphoribosyltransferase (NAMPT) inhibitors.

A. Massarotti, G. Tron, R. Rahimian, 2013, Journal of medicinal chemistry.

CTLA-4 rs231775 and risk of acute renal graft rejection: an updated meta-analysis with trial sequential analysis

S. Terrazzino, S. Cargnin, J. Shin, 2020, Scientific Reports.

α-Amino Acids as Synthons in the Ugi-5-Centers-4-Components Reaction: Chemistry and Applications

Ettore Novellino, Gian Cesare Tron, Sveva Pelliccia, 2019, Symmetry.

Synthesis and Characterization of Bis-Triazolyl-Pyridine Derivatives as Noncanonical DNA-Interacting Compounds

B. Pagano, D. Brancaccio, A. Carotenuto, 2021, International journal of molecular sciences.

Pyrtriazoles, a Novel Class of Store-Operated Calcium Entry Modulators: Discovery, Biological Profiling, and in Vivo Proof-of-Concept Efficacy in Acute Pancreatitis.

S. Cuzzocrea, D. Lim, R. Di Paola, 2018, Journal of medicinal chemistry.

Multicomponent Reaction Between (Z)-Chloroximes, Isocyanides And NH-Heterocyclic Rings

Francesca Brunelli, Camilla Russo, U. Galli, 2021, Tetrahedron Letters.

Identification of novel aza-analogs of TN-16 as disrupters of microtubule dynamics through a multicomponent reaction.

M. Corazzari, G. Tron, A. Genazzani, 2022, European journal of medicinal chemistry.