H. Elkady

发表

Detection of some Heavy Metals Using Rhodamine B Isothiocyanate Fluoresceinated Dye

E. Kilany, A. Azab, Z. Anwar, 2016 .

Multi-Step In Silico Discovery of Natural Drugs against COVID-19 Targeting Main Protease

S. M. Abou-Seri, I. Eissa, F. Youssef, 2022, International journal of molecular sciences.

A Multistage In Silico Study of Natural Potential Inhibitors Targeting SARS-CoV-2 Main Protease

I. Eissa, A. Metwaly, H. Elkady, 2022, International journal of molecular sciences.

Modified Benzoxazole-Based VEGFR-2 Inhibitors and Apoptosis Inducers: Design, Synthesis, and Anti-Proliferative Evaluation

I. Eissa, M. S. Taghour, Ahmed B. M. Mehany, 2022, Molecules.

Design, synthesis, in vitro biological assessment and molecular modeling insights for novel 3-(naphthalen-1-yl)-4,5-dihydropyrazoles as anticancer agents with potential EGFR inhibitory activity

H. Abdel‐Aziz, T. Al-Warhi, Wagdy M. Eldehna, 2022, Scientific Reports.

Benzoxazole derivatives as new VEGFR-2 inhibitors and apoptosis inducers: design, synthesis, in silico studies, and antiproliferative evaluation

M. M. Khalifa, I. Eissa, M. S. Taghour, 2022, Journal of enzyme inhibition and medicinal chemistry.

Design, synthesis, and biological evaluation of new challenging thalidomide analogs as potential anticancer immunomodulatory agents.

I. Eissa, M. El-Zahabi, Khaled El-Adl, 2020, Bioorganic chemistry.

Design, synthesis and molecular docking of new fused 1H-pyrroles, pyrrolo[3,2-d]pyrimidines and pyrrolo[3,2-e][1, 4]diazepine derivatives as potent EGFR/CDK2 inhibitors

Nagwa M. Abdel Gawad, A. Belal, Ahmed B. M. Mehany, 2022, Journal of enzyme inhibition and medicinal chemistry.

In silico, in vitro VEGFR-2 inhibition, and anticancer activity of a 3-(hydrazonomethyl)naphthalene-2-ol derivative

Ibrahim M. Ibrahim, I. Eissa, Ahmed B. M. Mehany, 2022, Journal of biomolecular structure & dynamics.

Design, synthesis, anti-proliferative evaluation, docking, and MD simulations studies of new thiazolidine-2,4-diones targeting VEGFR-2 and apoptosis pathway

Wagdy M. Eldehna, N. El-Deeb, I. Eissa, 2022, PloS one.

Design, Synthesis, Docking, DFT, MD Simulation Studies of a New Nicotinamide-Based Derivative: In Vitro Anticancer and VEGFR-2 Inhibitory Effects

Ibrahim M. Ibrahim, I. Eissa, A. Metwaly, 2022, Molecules.

Discovery of Some Heterocyclic Molecules as Bone Morphogenetic Protein 2 (BMP-2)-Inducible Kinase Inhibitors: Virtual Screening, ADME Properties, and Molecular Docking Simulations

M. Ghoneim, A. Belal, Ahmed B. M. Mehany, 2022, Molecules.

A New Theobromine-Based EGFRWT and EGFRT790M Inhibitor and Apoptosis Inducer: Design, Semi-Synthesis, Docking, DFT, MD Simulations, and In Vitro Studies

Ibrahim M. Ibrahim, I. Eissa, A. Metwaly, 2022, Processes.

New Anticancer Theobromine Derivative Targeting EGFRWT and EGFRT790M: Design, Semi-Synthesis, In Silico, and In Vitro Anticancer Studies

Ibrahim M. Ibrahim, I. Eissa, A. Metwaly, 2022, Molecules.

Discovery of new quinoline and isatine derivatives as potential VEGFR-2 inhibitors: design, synthesis, antiproliferative, docking and MD simulation studies.

Wagdy M. Eldehna, N. El-Deeb, I. Eissa, 2023, Journal of biomolecular structure & dynamics.

Modified pyrido[2,3-d]pyrimidin-4(3H)-one derivatives as EGFRWT and EGFRT790M inhibitors: Design, synthesis, and anti-cancer evaluation

Ibrahim M. Ibrahim, I. Eissa, M. El‐Manawaty, 2022, Journal of Molecular Structure.

Design and synthesis of thiazolidine-2,4-diones hybrids with 1,2-dihydroquinolones and 2-oxindoles as potential VEGFR-2 inhibitors: in-vitro anticancer evaluation and in-silico studies

Wagdy M. Eldehna, N. El-Deeb, I. Eissa, 2022, Journal of enzyme inhibition and medicinal chemistry.

Discovery of new quinoxaline-based derivatives as anticancer agents and potent VEGFR-2 inhibitors: Design, synthesis, and in silico study

Wael A Alanazi, M. Alanazi, I. Eissa, 2021, Journal of Molecular Structure.

New quinoxaline-based VEGFR-2 inhibitors: design, synthesis, and antiproliferative evaluation with in silico docking, ADMET, toxicity, and DFT studies

H. Alkahtani, M. Alanazi, I. Eissa, 2021, RSC advances.

New quinoxaline derivatives as VEGFR-2 inhibitors with anticancer and apoptotic activity: Design, molecular modeling, and synthesis.

M. Alanazi, Ahmad J. Obaidullah, Nawaf A. Alsaif, 2021, Bioorganic chemistry.

Discovery of thieno[2,3-d]pyrimidine-based derivatives as potent VEGFR-2 kinase inhibitors and anti-cancer agents.

I. Eissa, Ahmed B. M. Mehany, H. Elkady, 2021, Bioorganic chemistry.

Design, synthesis, docking, ADMET studies, and anticancer evaluation of new 3-methylquinoxaline derivatives as VEGFR-2 inhibitors and apoptosis inducers

Wael A Alanazi, M. Alanazi, I. Eissa, 2021, Journal of enzyme inhibition and medicinal chemistry.

Phthalazine-1,4-dione derivatives as non-competitive AMPA receptor antagonists: design, synthesis, anticonvulsant evaluation, ADMET profile and molecular docking

Khaled El-Adl, Abdel-Ghany A. El-Helby, R. Ayyad, 2018, Molecular Diversity.

Design, synthesis, in silico ADMET profile and GABA‐A docking of novel phthalazines as potent anticonvulsants

Khaled El-Adl, Abdel-Ghany A. El-Helby, Hamada S. Abulkhair, 2019, Archiv der Pharmazie.

A New Anticancer Semisynthetic Theobromine Derivative Targeting EGFR Protein: CADDD Study

Ibrahim M. Ibrahim, I. Eissa, A. Metwaly, 2023, Life.

New benzoxazole derivatives as potential VEGFR-2 inhibitors and apoptosis inducers: design, synthesis, anti-proliferative evaluation, flowcytometric analysis, and in silico studies

M. M. Khalifa, I. Eissa, M. S. Taghour, 2021, Journal of enzyme inhibition and medicinal chemistry.

Design, synthesis, and biological evaluation of novel bioactive thalidomide analogs as anticancer immunomodulatory agents

I. Eissa, M. El-Zahabi, M. S. Taghour, 2022, RSC advances.

Anticancer derivative of the natural alkaloid, theobromine, inhibiting EGFR protein: Computer-aided drug discovery approach

Ibrahim M. Ibrahim, I. Eissa, A. Metwaly, 2023, PloS one.

The Assessment of Anticancer and VEGFR-2 Inhibitory Activities of a New 1H-Indole Derivative: In Silico and In Vitro Approaches

Ibrahim M. Ibrahim, I. Eissa, A. Metwaly, 2022, Processes.

(E)-N-(3-(1-(2-(4-(2,2,2-Trifluoroacetamido)benzoyl)hydrazono)ethyl)phenyl)nicotinamide: A Novel Pyridine Derivative for Inhibiting Vascular Endothelial Growth Factor Receptor-2: Synthesis, Computational, and Anticancer Studies

Ibrahim M. Ibrahim, I. Eissa, A. Metwaly, 2022, Molecules.

Design, synthesis, anticancer evaluation, in silico docking and ADMET analysis of novel indole-based thalidomide analogs as promising immunomodulatory agents.

M. El-Zahabi, Khaled El-Adl, Helmy M. Sakr, 2023, Journal of biomolecular structure & dynamics.

Design and synthesis of new 4-(2-nitrophenoxy)benzamide derivatives as potential antiviral agents: molecular modeling and in vitro antiviral screening

Sara H Mahmoud, E. El‐Fakharany, A. A. Al-karmalawy, 2021, New Journal of Chemistry.

New apoptotic anti-triple-negative breast cancer theobromine derivative inhibiting EGFRWT and EGFRT790M: in silico and in vitro evaluation.

Ibrahim M. Ibrahim, Wagdy M. Eldehna, N. El-Deeb, 2023, Molecular diversity.

Semi-synthesized anticancer theobromine derivatives targeting VEGFR-2: in silico and in vitro evaluations.

Ibrahim M. Ibrahim, I. Eissa, M. S. Taghour, 2023, Journal of biomolecular structure & dynamics.

In vitro and in silico evaluation of new thieno[2,3-d]pyrimidines as anti-cancer agents and apoptosis inducers targeting VEGFR-2

Ibrahim M. Ibrahim, I. Eissa, M. S. Taghour, 2023, Comput. Biol. Chem..

Identification of new theobromine-based derivatives as potent VEGFR-2 inhibitors: design, semi-synthesis, biological evaluation, and in silico studies

Ibrahim M. Ibrahim, I. Eissa, A. Metwaly, 2023, RSC advances.

New theobromine derivative as apoptotic anti-triple-negative breast cancer targeting EGFR protein: CADD story

N. El-Deeb, I. Eissa, A. Metwaly, 2023, Journal of Molecular Structure.

Design, synthesis, in vitro biological assessment and molecular modeling insights for novel 3-(naphthalen-1-yl)-4,5-dihydropyrazoles as anticancer agents with potential EGFR inhibitory activity

H. Abdel‐Aziz, T. Al-Warhi, Wagdy M. Eldehna, 2022, Scientific Reports.

New thiazolidine-2,4-diones as effective anti-proliferative and anti-VEGFR-2 agents: Design, synthesis, in vitro, docking, MD simulations, DFT, ADMET, and toxicity studies

I. Eissa, A. Metwaly, Dalal Z. Husein, 2023, Computational Biology and Chemistry.

Design, synthesis, anti-proliferative evaluation, docking, and MD simulation studies of new thieno[2,3-d]pyrimidines targeting VEGFR-2

Ibrahim M. Ibrahim, I. Eissa, A. Metwaly, 2023, RSC advances.

Novel promising benzoxazole/benzothiazole‐derived immunomodulatory agents: Design, synthesis, anticancer evaluation, and in silico ADMET analysis

M. El-Zahabi, Khaled El-Adl, Helmy M. Sakr, 2023, Archiv der Pharmazie.

Design, synthesis, anticancer evaluation, and in silico ADMET analysis of novel thalidomide analogs as promising immunomodulatory agents

I. Eissa, M. El-Zahabi, H. Elkady, 2023, RSC advances.

Discovery of new VEGFR-2 inhibitors based on bis([1, 2, 4]triazolo)[4,3-a:3',4'-c]quinoxaline derivatives as anticancer agents and apoptosis inducers

M. Alanazi, Ahmad J. Obaidullah, Nawaf A. Alsaif, 2021, Journal of enzyme inhibition and medicinal chemistry.

Design, semi-synthesis, anti-cancer assessment, docking, MD simulation, and DFT studies of novel theobromine-based derivatives as VEGFR-2 inhibitors and apoptosis inducers.

Ibrahim M. Ibrahim, I. Eissa, A. Metwaly, 2023, Computational biology and chemistry.

New theobromine derivatives inhibiting VEGFR-2: design, synthesis, antiproliferative, docking and molecular dynamics simulations.

Ibrahim M. Ibrahim, I. Eissa, A. Metwaly, 2023, Future medicinal chemistry.

Multi-Phase In Silico Discovery of Potential SARS-CoV-2 RNA-Dependent RNA Polymerase Inhibitors among 3009 Clinical and FDA-Approved Related Drugs

Reem K. Arafa, I. Eissa, A. Belal, 2022, Processes.

Anti-breast cancer potential of a new xanthine derivative: in silico, antiproliferative, selectivity, VEGFR-2 inhibition, apoptosis induction and migration inhibition studies

I. Eissa, A. Metwaly, Dalal Z. Husein, 2023, Pathology - Research and Practice.

Synthesis, biological evaluation and computer-aided discovery of new thiazolidine-2,4-dione derivatives as potential antitumor VEGFR-2 inhibitors

Ibrahim M. Ibrahim, A. Darwish, I. Eissa, 2023, RSC Advances.

Computer-assisted drug discovery of potential natural inhibitors of the SARS-CoV-2 RNA-dependent RNA polymerase through a multi-phase in silico approach

Ibrahim M. Ibrahim, Reem K. Arafa, I. Eissa, 2023, Antiviral therapy.

A Theobromine Derivative with Anticancer Properties Targeting VEGFR‐2: Semisynthesis, in silico and in vitro Studies

Ibrahim M. Ibrahim, I. Eissa, A. Metwaly, 2023, ChemistryOpen.

Screening a Panel of Topical Ophthalmic Medications against MMP-2 and MMP-9 to Investigate Their Potential in Keratoconus Management

A. Belal, Ahmed B. M. Mehany, E. Santali, 2022, Molecules.

Novel Thiazolidine‐2,4‐Dione Derivatives as Potential VEGFR‐2 Inhibitors: Synthesis, Biological Testing, and in Silico Studies

I. Eissa, A. Metwaly, Dalal Z. Husein, 2024, ChemistrySelect.

Biological and computational assessment of new synthesized nicotinamides as potential immunomodulatory VEGFR-2 inhibitors

M. El-Zahabi, Ahmed B. M. Mehany, H. Elkady, 2024, Journal of Molecular Structure.

New modified thieno[2,3-d]pyrimidine derivatives as VEGFR-2 inhibitors: Design, synthesis, in vitro anti-cancer evaluation and divers in silico studies

I. Eissa, A. Metwaly, Dalal Z. Husein, 2024, Journal of Molecular Structure.

Computer-Assisted Drug Discovery of a Novel Theobromine Derivative as an EGFR Protein-Targeted Apoptosis Inducer

I. Eissa, A. Metwaly, Dalal Z. Husein, 2023, Evolutionary bioinformatics online.

Discovery of new thiazolidine-2,4-dione derivatives as potential VEGFR-2 inhibitors: In vitro and in silico studies

A. Metwaly, Dalal Z. Husein, H. Elkady, 2024, Heliyon.

Computer-assisted drug discovery (CADD) of an anti-cancer derivative of the theobromine alkaloid inhibiting VEGFR-2

I. Eissa, A. Metwaly, Dalal Z. Husein, 2023, Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society.

New vatalanib analogs: design, synthesis, in silico study and biological evaluation for anticancer activity

H. Elkady, Alaa Elwan, A. E. Abdallah, 2024, Journal of Molecular Structure.