J. Brocard

发表

Preparation of enantiopure 1,4-amino alcohols derived from [3]ferrocenophanes: use in the asymmetric addition of diethylzinc to benzaldehyde

Nadège Faux, D. Razafimahefa, Sophie Picart-Goetgheluck, 2005 .

Ferroquine, an Ingenious Antimalarial Drug –Thoughts on the Mechanism of Action

C. Biot, D. Dive, J. Khalife, 2008, Molecules.

Insights into the mechanism of action of ferroquine. Relationship between physicochemical properties and antiplasmodial activity.

D. Taramelli, T. Egan, C. Biot, 2005, Molecular pharmaceutics.

Structure–activity relationships of 4-N-substituted ferroquine analogues: Time to re-evaluate the mechanism of action of ferroquine

C. Biot, D. Dive, B. Pradines, 2009 .

Synthesis and antimycobacterial activity of ferrocenyl ethambutol analogues and ferrocenyl diamines.

J. Maugein, C. Bébéar, Lydie Pelinski, 2005, Bioorganic & medicinal chemistry letters.

Synthesis and antimalarial activity in vitro and in vivo of a new ferrocene-chloroquine analogue.

C. Biot, D. Dive, A. Georges, 1997, Journal of medicinal chemistry.

Trioxaferroquines as new hybrid antimalarial drugs.

L. Vendier, B. Meunier, A. Robert, 2010, Journal of medicinal chemistry.

Selective palladium-catalysed carbonylations of dichloroquinoline and simple dichloropyridines

C. Biot, A. Mortreux, Y. Castanet, 1999 .

Probing the role of the covalent linkage of ferrocene into a chloroquine template.

C. Biot, D. Dive, B. Pradines, 2006, Journal of medicinal chemistry.

Synthesis and in vitro activities of ferrocenic aminohydroxynaphthoquinones against Toxoplasma gondii and Plasmodium falciparum.

M. Mortuaire, S. Tomavo, Lydie Pelinski, 2006, Bioorganic & medicinal chemistry.

Synthesis and chloroquine-enhancing activity of Na-deacetyl-ferrocenoyl-strychnobrasiline.

P. Rasoanaivo, D. Ramanitrahasimbola, Lydie Pelinski, 2005, Bioorganic & medicinal chemistry letters.

In vitro susceptibility to a new antimalarial organometallic analogue, ferroquine, of Plasmodium falciparum isolates from the Haut-Ogooué region of Gabon.

P. Deloron, A. Aubouy, C. Attéké, 2003, The Journal of antimicrobial chemotherapy.

Synthesis of Ferroquine Enantiomers: First Investigation of Effects of Metallocenic Chirality upon Antimalarial Activity and Cytotoxicity

C. Biot, D. Dive, L. Delhaes, 2002, Chembiochem : a European journal of chemical biology.

In vitro and in vivo antimalarial activity of ferrochloroquine, a ferrocenyl analogue of chloroquine against chloroquine-resistant malaria parasites

C. Biot, D. Dive, L. Delhaes, 2001, Parasitology Research.

Chiral ferrocenyl amino alcohols for enantioselective additions of diethylzinc to aldehydes

M. Ginj, Lydie Pelinski, Stéphanie Bastin, 2003 .

Enantioselective alkylation of benzaldehyde with diethylzinc catalyzed by 1,1′- and 1,2-disubstituted ferrocenyl amino alcohols

F. Agbossou-Niedercorn, Lydie Pelinski, Stéphanie Bastin, 2001 .

Chiral ferrocenyl amino alcohols as analogues of norephedrine catalysts for enantioselective addition of diethylzinc to benzaldehyde

Lydie Pelinski, Stéphanie Bastin, J. Brocard, 2000 .

Synthesis of chiral ferrocenyl aminoalcohols involving a diastereospecific oxidation: use in asymmetric catalysis

Sophie Picart-Goetgheluck, J. Brocard, L. Maciejewski, 1999 .

Synthesis of C2-symmetrical 1,1′-disubstituted ferrocenyl amino alcohols and use in catalytic asymmetric addition of diethylzinc to benzaldehyde

Lydie Pelinski, Stéphanie Bastin, J. Brocard, 1999 .

Enantioselective synthesis and use in catalytic asymmetric addition of diethylzinc to benzaldehyde of new chiral cyclic hydroxyamino ferrocene and chromium complexes: influence of the complexation on the enantioselectivity

Lydie Pelinski, J. Brocard, Stéphane Malfait, 1998 .

Chiral ferrocenyl amino alcohols as catalysts for the enantioselective borane reduction of ketones

Lydie Pelinski, Stéphanie Bastin, J. Brocard, 2002 .

Chiral tricarbonyl(η6-arene)chromium complexed diphosphanes. Highly enantioselective rhodium-mediated hydrogenation of ketones

A. Mortreux, F. Agbossou-Niedercorn, Lydie Pelinski, 2001 .

In Vitro Antimalarial Activity of a New Organometallic Analog, Ferrocene-Chloroquine

C. Biot, A. Georges, P. Millet, 1998, Antimicrobial Agents and Chemotherapy.

Competitive nucleophilic aromatic substitution and palladium-catalyzed alkoxycarbonylation of (substituted chloroarene)Cr(CO)3 complexes

A. Mortreux, Y. Castanet, J. Carpentier, 1994 .

Palladium-Catalysed Alkoxycarbonylation of Tricarbonyl(η6- mono and dichloroarene)chromium Complexes under Mild Conditions using HCO2R / MOR System

A. Mortreux, Y. Castanet, J. Carpentier, 1992 .

A novel and convenient method for palladium-catalysed alkoxycarbonylation of aryl and vinyl halides using HCO2R/NaOR system

A. Mortreux, Y. Castanet, J. Carpentier, 1991 .

Synthesis and antifungal activity of a ferrocene-fluconazole analogue.

C. Biot, D. Poulain, N. François, 2000, Bioorganic & medicinal chemistry letters.

Synthetic ferrocenic mefloquine and quinine analoguesas potential antimalarial agents.

C. Biot, D. Dive, M. Mortuaire, 2000, European journal of medicinal chemistry.

Synthesis and antimalarial activity in vitro of potential metabolites of ferrochloroquine and related compounds.

C. Biot, D. Dive, L. Delhaes, 1999, Bioorganic & medicinal chemistry.

Influence of the Tricarbonyl Chromium Complexation of Cyclic Alcohols and of the Planar Chirality on the Kinetic Resolution by Candida Cylindracea Lipase

Lydie Pelinski, J. Brocard, Stéphane Malfait, 1998 .

Stereoselective synthesis and use in catalytic asymmetric addition of diethylzinc to benzaldehyde of new chiral amino alcohol complexes: Influence of the chromium complexation on the enantioselectivity

Lydie Pelinski, J. Brocard, Stéphane Malfait, 1996 .

Kinetic resolution of racemic tricarbonyl(2-chloroanisole)chromium via palladium-catalysed asymmetric alkoxycarbonylation

A. Mortreux, Y. Castanet, J. Carpentier, 1996 .

Highly regio- and stereo-controlled hydroformylation of ortho-substituted (η6-styrene)chromium complexes

A. Mortreux, H. Bricout, S. Naili, 1994 .

Diastereocontrol of η4-α,β-unsaturated ketone–Fe(CO)3 complexation by an adjacent metal-complexed chiral centre

F. Baert, J. Brocard, L. Maciejewski, 1990 .

Reaction de Reformatsky diastrospcifique sur un aldhyde arne chrome tricarbonyle chiral

J. Brocard, 1987 .

Fonctionnalisation benzylique en serie arene chrome tricarbonyle. Influence des substituants diakylamino et chloro sur la régiospécificité et la stéréospécificité de la réaction

J. Lébibi, Lydie Pelinski, J. Brocard, 1986 .

Regiospecific and stereospecific functionalization of benzylic sites by tricarbonylchromium arene complexation

G. Jaouen, S. Top, D. Couturier, 1984 .

Benzylic functionalization of arene(tricarbonyl)chromium complexes

J. Lébibi, D. Couturier, J. Brocard, 1981 .

Novel ferrocenic artemisinin derivatives: synthesis, in vitro antimalarial activity and affinity of binding with ferroprotoporphyrin IX.

D. Dive, L. Delhaes, C. Blot, 2000, Bioorganic & medicinal chemistry.

Novel metallocenic compounds as antimalarial agents. Study of the position of ferrocene in chloroquine

C. Biot, D. Dive, M. Mortuaire, 1999 .

Free and Cr(CO)3-Complexed Aminophosphine Phosphinite Ligands for Highly Enantioselective Hydrogenation of α-Functionalized Ketones

A. Mortreux, J. Martens, S. Naili, 2000 .

Chiral Ferrocenyl Amino Alcohols as Catalysts for the Enantioselective Borane Reduction of Ketones.

Lydie Pelinski, Stéphanie Bastin, J. Brocard, 2002 .

Assessment of Plasmodium falciparum resistance to ferroquine (SSR97193) in field isolates and in W2 strain under pressure

C. Biot, D. Dive, B. Pradines, 2006, Malaria Journal.

Chiral ferrocenyl diphosphines for asymmetric transfer hydrogenation of acetophenone

Lydie Pelinski, J. Brocard, J. Cabou, 2005 .

Highly stereoselective alkylation through asymmetric intramolecular autoactivation; synthesis and use of a new chiral ligand

J. Brocard, L. Maciejewski, O. Delacroix, 1996 .

Chiral Tricarbonyl(η6‐arene)chromium Complexed Diphosphanes. Highly Enantioselective Rhodium‐Mediated Hydrogenation of Ketones.

A. Mortreux, F. Agbossou-Niedercorn, Lydie Pelinski, 2001 .

SYNTHESIS AND APPLICATION IN ENANTIOSELECTIVE HYDROGENATION OF NEW FREE AND CHROMIUM COMPLEXED AMINOPHOSPHINE-PHOSPHINITE LIGANDS

A. Mortreux, S. Naili, Lydie Pelinski, 1998 .

Molecular modelling of (η6-arene)–Cr(CO)3 complex systems

G. Vergoten, G. Surpateanu, A. Elass, 1999 .

Molecular modelling of the polysubstitued (η6-arene)-Cr(CO)3 complex systems: application to the (η6-arene)-Cr(CO)3 systems reactivity

G. Vergoten, G. Surpateanu, A. Elass, 1999 .

Molecular modelling of (η6-arene)–Cr(CO)3 complex systems: force field development of the monosubstituted complexes

G. Vergoten, G. Surpateanu, A. Elass, 1999 .

Oxidative addition of cationic (η6-chloroarene)tricarbonylmanganese compounds to palladium(0) complexes. Synthesis, characterisation and reactivity

E. Rose, A. Mortreux, Y. Castanet, 1995 .

A Convenient Route to Norpyrenophorin

G. Ricart, J. Brocard, L. Maciejewski, 1988 .

1H NMR conformational analysis of disubstituted arene tricarbonyl chromium complexes

D. Couturier, J. Brocard, Alain Laconi, 1984 .

IN VITRO METABOLISM OF FERROQUINE (SSR97193) IN ANIMAL AND HUMAN HEPATIC MODELS AND ANTIMALARIAL ACTIVITY OF MAJOR METABOLITES ON PLASMODIUM FALCIPARUM

Christophe Biot, Laurent Fraisse, C. Biot, 2006, Drug Metabolism and Disposition.

Enantioselective synthesis of (R)- and (S)-1-ferrocenylalkylamines. Reduction of enantiopure ferrocenylimines obtained from valinol and phenylglycinol

J. Brocard, Francine Agbossou, L. Maciejewski, 1997 .

Synthesis and characterisation of a double deuterium‐labelled ferrochloroquine

C. Biot, J. Brocard, L. Maciejewski, 1998 .

Analysis of immune response patterns in naïve and Plasmodium berghei-infected young rats following a ferroquine treatment.

D. Dive, L. Fraisse, J. Khalife, 2005, International journal for parasitology.

Synthetic Ferrocenic Mefloquine and Quinine Analogues as Potential Antimalarial Agents.

C. Biot, D. Dive, M. Mortuaire, 2000 .

High Yield Synthesis of 2-Substituted (N,N-Dimethylaminomethyl)ferrocenes

Sophie Picart-Goetgheluck, J. Brocard, L. Maciejewski, 2000 .

Malaria Journal Assessment of Plasmodium Falciparum Resistance to Ferroquine (ssr97193) in Field Isolates and in W2 Strain under Pressure

C. Biot, D. Dive, B. Pradines, 2022 .