E. Ruben

发表

Ground state destabilization from a positioned general base in the ketosteroid isomerase active site.

D. Herschlag, J. Schwans, M. Sonnett, 2013, Biochemistry.

The active site cysteine of arginine kinase: structural and functional analysis of partially active mutants.

M. S. Chapman, W. Ellington, M. O. Fenley, 2004, Biochemistry.

Sclerotiamide: The First Non-Peptide-Based Natural Product Activator of Bacterial Caseinolytic Protease P.

A. Duerfeldt, J. Coker, E. Ruben, 2016, Journal of natural products.

The J-elongated conformation of β2-glycoprotein I predominates in solution: implications for our understanding of antiphospholipid syndrome

Zhiwei Chen, X. Zuo, V. De Filippis, 2020, The Journal of Biological Chemistry.

19F NMR reveals the conformational properties of free thrombin and its zymogen precursor prethrombin-2

E. Di Cera, P. S. Gandhi, Zhiwei Chen, 2020, The Journal of Biological Chemistry.

Anomeric effect in "high energy" phosphate bonds. Selective destabilization of the scissile bond and modulation of the exothermicity of hydrolysis.

Joshua A. Plumley, M. S. Chapman, J. Evanseck, 2008, Journal of the American Chemical Society.

Determination of Hydrogen Bond Structure in Water versus Aprotic Environments To Test the Relationship Between Length and Stability.

T. Martínez, D. Herschlag, Corey W. Liu, 2015, Journal of the American Chemical Society.

In silico investigation of FOXM1 binding and novel inhibitors in epithelial ovarian cancer.

J. Rajadas, N. Teng, E. Ruben, 2015, Bioorganic & medicinal chemistry.

Testing geometrical discrimination within an enzyme active site: constrained hydrogen bonding in the ketosteroid isomerase oxyanion hole.

Daniel Herschlag, Gregory A Petsko, Jose M M Caaveiro, 2008, Journal of the American Chemical Society.

X-ray and solution structures of human beta-2 glycoprotein I reveal a new mechanism of autoantibody recognition

Zhiwei Chen, X. Zuo, V. Filippis, 2020, bioRxiv.

Cryo-EM structures of human coagulation factors V and Va.

E. Di Cera, J. Fitzpatrick, M. Rau, 2021, Blood.

Exploring purine N7 interactions via atomic mutagenesis: the group I ribozyme as a case study.

D. Herschlag, Tara L. Benz-Moy, M. Forconi, 2012, RNA.

Annexin-directed &bgr;-glucuronidase for the targeted treatment of solid tumors

R. Harrison, N. Virani, Katrin P. Guillen, 2017, Protein engineering, design & selection : PEDS.

Cryo-EM structure of the prothrombin-prothrombinase complex

E. Di Cera, B. Summers, M. Rau, 2022, Blood.

Cryo-EM structures of Uba7 reveal the molecular basis for ISG15 activation and E1-E2 thioester transfer

S. Olsen, E. Wasmuth, Lijia Jia, 2023, Nature communications.

Structural insights into BCDX2 complex function in homologous recombination

E. Greene, S. Burma, Alexander B. Taylor, 2023, Nature.

Generalized anomeric interpretation of the "high-energy" N-P bond in N-methyl-N'-phosphorylguanidine: importance of reinforcing stereoelectronic effects in "high-energy" phosphoester bonds.

M. S. Chapman, J. Evanseck, E. Ruben, 2005, Journal of the American Chemical Society.