Jun Zhu

发表

Nicotinic Receptor Activation Increases [3H]Dopamine Uptake and Cell Surface Expression of Dopamine Transporters in Rat Prefrontal Cortex

S. Apparsundaram, L. Dwoskin, Jun Zhu, 2009, Journal of Pharmacology and Experimental Therapeutics.

Allosteric modulatory effects of SRI-20041 and SRI-30827 on cocaine and HIV-1 Tat protein binding to human dopamine transporter

C. Zhan, S. Ananthan, Yaxia Yuan, 2017, Scientific Reports.

HIV-1 Tat Protein Decreases Dopamine Transporter Cell Surface Expression and Vesicular Monoamine Transporter-2 Function in Rat Striatal Synaptosomes

A. Gomez, Narasimha M. Midde, Jun Zhu, 2012, Journal of Neuroimmune Pharmacology.

Inhibition of the Dead Box RNA Helicase 3 Prevents HIV-1 Tat and Cocaine-Induced Neurotoxicity by Targeting Microglia Activation

Ilya Safro, E. Peña, M. Shtutman, 2019, Journal of Neuroimmune Pharmacology.

Inhibition of the Dead Box RNA Helicase 3 Prevents HIV-1 Tat and Cocaine-Induced Neurotoxicity by Targeting Microglia Activation

Ilya Safro, E. Peña, M. Shtutman, 2019, bioRxiv.

Effects of environmental enrichment on behavior and dopamine transporter function in medial prefrontal cortex in adult rats prenatally treated with cocaine.

L. Dwoskin, N. Neugebauer, L. Middleton, 2004, Brain research. Developmental brain research.

Mitochondrial toxin inhibition of [(3)H]dopamine uptake into rat striatal synaptosomes.

L. Dwoskin, W. Maragos, Jun Zhu, 2002, Biochemical pharmacology.

Inhibition of Dopamine Transporter Activity by G Protein βγ Subunits

S. Amara, W. A. Owens, L. Daws, 2013, PloS one.

Lobelane analogues as novel ligands for the vesicular monoamine transporter-2.

L. Dwoskin, P. Crooks, Guangrong Zheng, 2005, Bioorganic & medicinal chemistry.

Mutation of Tyrosine 470 of Human Dopamine Transporter is Critical for HIV-1 Tat-Induced Inhibition of Dopamine Transport and Transporter Conformational Transitions

C. Zhan, A. Gomez, Xiaoqin Huang, 2013, Journal of Neuroimmune Pharmacology.

Mutations of Human DopamineTransporter at Tyrosine88, Aspartic Acid206, and Histidine547 Influence Basal and HIV-1 Tat‐inhibited Dopamine Transport

C. Zhan, Yaxia Yuan, Pamela M Quizon, 2021, Journal of Neuroimmune Pharmacology.

SRI-32743, a novel allosteric modulator, attenuates HIV-1 Tat protein-induced inhibition of the dopamine transporter and alleviates the potentiation of cocaine reward in HIV-1 Tat transgenic mice

C. Zhan, S. Ananthan, T. Cirino, 2022, Neuropharmacology.

Mutations of tyrosine 467 in the human norepinephrine transporter attenuate HIV-1 Tat-induced inhibition of dopamine transport while retaining physiological function

C. Zhan, Yaxia Yuan, Pamela M Quizon, 2022, PloS one.

Flipped Phenyl Ring Orientations of Dopamine Binding with Human and Drosophila Dopamine Transporters: Remarkable Role of Three Nonconserved Residues.

C. Zhan, Yaxia Yuan, Jun Zhu, 2018, ACS chemical neuroscience.

Mutations at Tyrosine 88, Lysine 92 and Tyrosine 470 of Human Dopamine Transporter Result in an Attenuation of HIV-1 Tat-Induced Inhibition of Dopamine Transport

C. Zhan, Yaxia Yuan, Xiaoqin Huang, 2015, Journal of Neuroimmune Pharmacology.

Molecular Mechanism: ERK Signaling, Drug Addiction, and Behavioral Effects.

Pamela M Quizon, Wei-Lun Sun, Jun Zhu, 2016, Progress in molecular biology and translational science.

Genetically expressed HIV-1 viral proteins attenuate nicotine-induced behavioral sensitization and alter mesocorticolimbic ERK and CREB signaling in rats

A. Gomez, Narasimha M. Midde, S. B. Harrod, 2011, Pharmacology Biochemistry and Behavior.

Intra-ventral tegmental area HIV-1 Tat1–86 attenuates nicotine-mediated locomotor sensitization and alters mesocorticolimbic ERK and CREB signaling in rats

A. Gomez, Narasimha M. Midde, Wei-Lun Sun, 2015, Front. Microbiol..

HIV-1 Tat Protein Decreases Dopamine Transporter Cell Surface Expression and Vesicular Monoamine Transporter-2 Function in Rat Striatal Synaptosomes

A. Gomez, Narasimha M. Midde, Jun Zhu, 2012, Journal of Neuroimmune Pharmacology.

HIV-1 Tat Protein-Induced Rapid and Reversible Decrease in [3H]Dopamine Uptake: Dissociation of [3H]Dopamine Uptake and [3H]2β-Carbomethoxy-3-β-(4-fluorophenyl)tropane (WIN 35,428) Binding in Rat Striatal Synaptosomes

D. Wallace, C. Mactutus, R. Booze, 2009, Journal of Pharmacology and Experimental Therapeutics.

HIV-1 Tat Protein-Induced Rapid and Reversible Decrease in [ 3 H]Dopamine Uptake: Dissociation of [ 3 H]Dopamine Uptake and [ 3 H]2 (cid:1) -Carbomethoxy-3- (cid:1) -(4-fluorophenyl)tropane (WIN 35,428) Binding in Rat Striatal Synaptosomes

D. Wallace, C. Mactutus, R. Booze, 2009 .

Prefrontal microRNA-221 Mediates Environmental Enrichment-Induced Increase of Locomotor Sensitivity to Nicotine

M. Shtutman, K. Creek, A. Gomez, 2015, The international journal of neuropsychopharmacology.

Novel allosteric modulator SRI-32743 reverses HIV-1 Tat-induced increase in dopamine release in the caudate putamen of inducible Tat transgenic mice.

S. Ananthan, M. Ferris, C. Augelli-Szafran, 2022, The Journal of pharmacology and experimental therapeutics.

Substance abuse and neurotransmission

Jun Zhu, S. Davis, 2022, Advances in pharmacology.

Binding Mode of Human Norepinephrine Transporter Interacting with HIV-1 Tat.

C. Zhan, Yaxia Yuan, Jun Zhu, 2021, ACS chemical neuroscience.

The role of human dopamine transporter in NeuroAIDS☆

C. Zhan, S. Ananthan, Jun Zhu, 2017, Pharmacology & therapeutics.

Role of Histidine 547 of Human Dopamine Transporter in Molecular Interaction with HIV-1 Tat and Dopamine Uptake

C. Zhan, Yaxia Yuan, Jianzhuang Yao, 2016, Scientific Reports.

Molecular mechanism of HIV-1 Tat interacting with human dopamine transporter.

C. Zhan, Yaxia Yuan, Xiaoqin Huang, 2015, ACS chemical neuroscience.

Recombinant human immunodeficiency virus‐1 transactivator of transcription1–86 allosterically modulates dopamine transporter activity

S. Ananthan, C. Mactutus, R. Booze, 2011, Synapse.

HIV-1 Tat protein-induced rapid and reversible decrease in [ 3 H ] dopamine uptake : dissociation of [ 3 H ] dopamine uptake and [ 3 H ] WIN 35 , 428 binding in rat striatal synaptosomes

D. Wallace, C. Mactutus, R. Booze, 2009 .

Behavioral recovery following sub-chronic paeoniflorin administration in the striatal 6-OHDA lesion rodent model of Parkinson's disease.

Xing-zu Zhu, Chunping Tang, X. Ji, 2007, Journal of ethnopharmacology.

Gestational IV nicotine produces elevated brain‐derived neurotrophic factor in the mesocorticolimbic dopamine system of adolescent rat offspring

Jun Zhu, Ryan T Lacy, Steven B Harrod, 2011, Synapse.

Effects of environmental enrichment on ERK1/2 phosphorylation in the rat prefrontal cortex following nicotine‐induced sensitization or nicotine self‐administration

A. Gomez, Narasimha M. Midde, Wei-Lun Sun, 2015, The European journal of neuroscience.

RACK1 upregulation induces neuroprotection by activating the IRE1-XBP1 signaling pathway following traumatic brain injury in rats

Fan Gao, H. Ni, Gang Chen, 2018, Experimental Neurology.

Subtype-selective nicotinic receptor antagonists: potential as tobacco use cessation agents.

L. Dwoskin, P. Crooks, A. Deaciuc, 2004, Bioorganic & medicinal chemistry letters.

Chronic nicotine treatment delays the developmental increase in brain muscarinic receptors in rat neonate

Y. Konishi, I. Muramatsu, Jun Zhu, 1996, Brain Research.

Introduction of unsaturation into theN-n-alkyl chain of the nicotinic receptor antagonists, NONI and NDNI: Effect on affinity and selectivity

L. Dwoskin, P. Crooks, A. Deaciuc, 2005, The AAPS Journal.

Effect of environmental enrichment on methylphenidate-induced locomotion and dopamine transporter dynamics

L. Dwoskin, M. Bardo, A. Gomez, 2011, Behavioural Brain Research.

Nicotine dynamically modulates dopamine clearance in rat striatum in vivo

Zhuan Zhou, Xinjiang Kang, Jun Zhu, 2012, Neurochemistry International.

Environmental enrichment enhances sensitization to GBR 12935-induced activity and decreases dopamine transporter function in the medial prefrontal cortex

L. Dwoskin, M. Bardo, T. Green, 2004, Behavioural Brain Research.

Computational modeling of human dopamine transporter structures, mechanism and its interaction with HIV-1 transactivator of transcription.

C. Zhan, Yaxia Yuan, Xiaoqin Huang, 2016, Future medicinal chemistry.

Mutational effects of human dopamine transporter at tyrosine88, lysine92, and histidine547 on basal and HIV-1 Tat-inhibited dopamine transport

C. Zhan, Yaxia Yuan, Wei-Lun Sun, 2019, Scientific Reports.

Mutation of Tyrosine 470 of Human Dopamine Transporter is Critical for HIV-1 Tat-Induced Inhibition of Dopamine Transport and Transporter Conformational Transitions

C. Zhan, A. Gomez, Xiaoqin Huang, 2013, Journal of Neuroimmune Pharmacology.

Nicotine increases dopamine clearance in medial prefrontal cortex in rats raised in an enriched environment

L. Dwoskin, M. Bardo, T. Green, 2007, Journal of neurochemistry.

Mutations at Tyrosine 88, Lysine 92 and Tyrosine 470 of Human Dopamine Transporter Result in an Attenuation of HIV-1 Tat-Induced Inhibition of Dopamine Transport

C. Zhan, Yaxia Yuan, Xiaoqin Huang, 2015, Journal of Neuroimmune Pharmacology.

bis-azaaromatic quaternary ammonium analogues: Ligands for α4β2* and α7* subtypes of neuronal nicotinic receptors

L. Dwoskin, P. Crooks, A. Deaciuc, 2002 .

Environmental enrichment decreases cell surface expression of the dopamine transporter in rat medial prefrontal cortex

S. Apparsundaram, L. Dwoskin, M. Bardo, 2005, Journal of neurochemistry.

HIV-1 transgenic rats display an increase in [3H]dopamine uptake in the prefrontal cortex and striatum

C. Zhan, Yaxia Yuan, A. Gomez, 2016, Journal of NeuroVirology.

Environmental Enrichment Alters Nicotine-Mediated Locomotor Sensitization and Phosphorylation of DARPP-32 and CREB in Rat Prefrontal Cortex

A. Gomez, C. Mactutus, R. Booze, 2012, PloS one.

Individual differences in response to novelty predict prefrontal cortex dopamine transporter function and cell surface expression

L. Dwoskin, M. Bardo, Jun Zhu, 2007, The European journal of neuroscience.

Molecular mechanism: the human dopamine transporter histidine 547 regulates basal and HIV-1 Tat protein-inhibited dopamine transport

C. Zhan, Yaxia Yuan, Narasimha M. Midde, 2016, Scientific Reports.

Distinct effects of enriched environment on dopamine clearance in nucleus accumbens shell and core following systemic nicotine administration

L. Dwoskin, M. Bardo, Jun Zhu, 2013, Synapse.

[3H]Dopamine Uptake through the Dopamine and Norepinephrine Transporters is Decreased in the Prefrontal Cortex of Transgenic Mice Expressing HIV-1 Transactivator of Transcription Protein

M. Bardo, J. McLaughlin, P. Ortinski, 2020, The Journal of Pharmacology and Experimental Therapeutics.

N‐n‐alkylnicotinium and N‐n‐alkylpyridinium analogs inhibit the dopamine transporter: Selectivity as nicotinic receptor antagonists

L. Dwoskin, P. Crooks, P. Crooks, 2003 .

Gestational IV nicotine produces elevated brain‐derived neurotrophic factor in the mesocorticolimbic dopamine system of adolescent rat offspring

Ryan T Lacy, Marla K. Perna, Russell W. Brown, 2011, Synapse.

Inhibition of the Dead Box RNA Helicase 3 Prevents HIV-1 Tat and Cocaine-Induced Neurotoxicity by Targeting Microglia Activation

Edsel A. Peña, Ilya Safro, M. Shtutman, 2019, Journal of Neuroimmune Pharmacology.

Nicotine dynamically modulates dopamine clearance in rat striatum in vivo

Zhuan Zhou, Xinjiang Kang, Jun Zhu, 2012, Neurochemistry International.

HIV-1 transgenic rats display an increase in [3H]dopamine uptake in the prefrontal cortex and striatum

C. Zhan, Yaxia Yuan, A. Gomez, 2015, Journal of NeuroVirology.