E. Littler

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Diagnosis of nasopharyngeal carcinoma by means of recombinant Epstein-Barr virus proteins

Yi Zeng, J. Arrand, M. Mackett, 1991, The Lancet.

The Use of Antisera to the Human Herpesvirus 6 Major Capsid Protein to Determine the Effect of Antiviral Inhibitors on Virus Gene Expression

J. Arrand, M. Liu, E. Littler, 1990 .

Characterization of the EBV Thymidine Kinase

J. Arrand, E. Littler, 1987 .

Ganciclovir and Penciclovir, but Not Acyclovir, Induce Apoptosis in Herpes Simplex Virus Thymidine Kinasetransformed Baby Hamster Kidney Cells

P. Watts, E. Littler, M. Shaw, 2001, Antiviral chemistry & chemotherapy.

Antibodies to Epstein‐Barr virus thymidine kinase: A characteristic marker for the serological detection of nasopharyngeal carcinoma

S. Stacey, J. Arrand, Y. Connolly, 2001, International journal of cancer.

High-level expression of the Epstein-Barr virus alkaline deoxyribonuclease using a recombinant baculovirus: application to the diagnosis of nasopharyngeal carcinoma.

S. Baylis, D. Purifoy, E. Littler, 1991, Virology.

Diagnosis of Nasopharyngeal Carcinoma Using the Epstein-Barr Virus Coded Alkaline Dnase, Membrane Antigen and Thymidine Kinase

Yi Zeng, J. Arrand, M. Mackett, 1991 .

A Randomized, Placebo-Controlled, Respiratory Syncytial Virus Human Challenge Study of the Antiviral Efficacy, Safety, and Pharmacokinetics of RV521, an Inhibitor of the RSV-F Protein

Young-In Kim, L. Wilson, J. Devincenzo, 2019, Antimicrobial Agents and Chemotherapy.

7.11 – Deoxyribonucleic Acid Viruses: Antivirals for Herpesviruses and Hepatitis B Virus

X.-X. Zhou, E. Littler, 2007 .

The genome of human herpesvirus 6: maps of unit-length and concatemeric genomes for nine restriction endonucleases.

M. Craxton, U. Gompels, M. Martín, 1991, The Journal of general virology.

The cloning, sequencing and expression of a major antigenic region from the feline calicivirus capsid protein.

A. Fox, M. Guiver, E. Caul, 1992, The Journal of general virology.

Immunological conservation between Epstein-Barr virus and herpes simplex virus.

K. Powell, J. Arrand, I. Halliburton, 1988, The Journal of general virology.

Identification, Cloning, andExpression oftheMajorCapsid Protein GeneofHumanHerpesvirus 6

E. Littler, G. Lawrence, 1990 .

Herpes simplex virus non-structural proteins. III. Function of the major DNA-binding protein.

K. Powell, A. Minson, D. Purifoy, 1983, The Journal of general virology.

Antigenic and structural conservation of herpesvirus DNA-binding proteins.

R. A. Killington, K. Powell, D. Purifoy, 1981, The Journal of general virology.

Identification, cloning, and expression of the major capsid protein gene of human herpesvirus 6

B. Barrell, J. Arrand, M. Liu, 1990, Journal of virology.

Immunological response of nasopharyngeal carcinoma patients to the Epstein‐Barr‐virus‐coded thymidine kinase expressed in Escherichia coli

J. Arrand, E. Littler, W. Newman, 1990, International journal of cancer.

Immunological studies on the Epstein-Barr virus encoded alkaline deoxyribonuclease found in virus-producing lymphoblastoid cells.

L. Young, S. Baylis, D. Purifoy, 1991, The Journal of general virology.

Characterization of the Epstein-Barr virus-encoded thymidine kinase expressed in heterologous eucaryotic and procaryotic systems

J. Arrand, E. Littler, 1988, Journal of virology.

A Randomized, Placebo-Controlled, Respiratory Syncytial Virus Human Challenge Study of the Antiviral Efficacy, Safety, and Pharmacokinetics of RV521, an Inhibitor of the RSV-F Protein

Young-In Kim, L. Wilson, J. Devincenzo, 2019, Antimicrobial Agents and Chemotherapy.

Vectors with multiple insertion sites for expression of cloned genes by T7 RNA polymerase: expression of a peptide from EBV thymidine kinase (TK).

J. Arrand, M. Mackett, E. Littler, 1990, Nucleic acids research.

CHARACTERIZATION OF THE EBV ALKALINE EXONUCLEASE EXPRESSED IN A RECOMBINANT PROKARYOTIC SYSTEM

S. Baylis, D. Purifoy, E. Littler, 1989 .

Indolocarbazoles: potent, selective inhibitors of human cytomegalovirus replication.

R. Baxter, W. Snowden, M. Slater, 1999, Bioorganic & medicinal chemistry.

Nucleoside analogs as anti-HBV agents.

E. Littler, Xiao-Xiong Zhou, 2006, Current topics in medicinal chemistry.

Synthesis and anti-herpes virus activity of 2'-deoxy-4'-thiopyrimidine nucleosides.

R. T. Walker, G. Hardy, W. Snowden, 1996, Journal of medicinal chemistry.

Human cytomegalovirus UL97 open reading frame encodes a protein that phosphorylates the antiviral nucleoside analogue ganciclovir

M. Chee, A. Stuart, E. Littler, 1992, Nature.

A Comparative Study of the in vitro and in vivo Antiviral Activities of Acyclovir and Penciclovir

W. Miller, W. Snowden, P. Collins, 1995 .

Nonstructural proteins of herpes simplex virus. II. Major virus-specific DNa-binding protein

K. Powell, D. Purifoy, E. Littler, 1981, Journal of virology.

Synthesis and Anti‐Herpes Virus Activity of 2′‐Deoxy‐4′‐thiopyrimidine Nucleosides.

R. T. Walker, G. Hardy, W. Snowden, 1996 .

Achievements and Challenges in Antiviral Drug Discovery

B. Oberg, E. Littler, 2005, Antiviral chemistry & chemotherapy.

Safety and efficacy issues of herpesvirus drugs

E. Littler, 1994 .

Temporal pattern of herpes simplex virus type 1 infection and cell death in the mouse brain stem: influence of guanosine nucleoside analogues.

H. Field, M. Shaw, P. Watts, 2002, Journal of virological methods.

The characterization of the EBV alkaline deoxyribonuclease cloned and expressed in E. coli.

S. Baylis, D. Purifoy, E. Littler, 1989, Nucleic acids research.

Identification of an Epstein‐Barr virus‐coded thymidine kinase.

J. Zeuthen, K. Powell, J. Arrand, 1986, The EMBO journal.

Clostridium difficile has a single sortase, SrtB, that can be inhibited by small-molecule inhibitors

B. Wren, E. Valiente, S. Firth-Clark, 2014, BMC Microbiology.

Discovery of Sisunatovir (RV521), an Inhibitor of Respiratory Syncytial Virus Fusion.

Sara M. Johnson, C. Scott, R. Angell, 2021, Journal of medicinal chemistry.

Nonstructural Proteins ofHerpes Simplex Virus II. MajorVirus-Specific DNA-Binding Protein

E. Littler, 1981 .

Combinatorial Domain Hunting: solving problems in protein expression.

E. Littler, 2010, Drug discovery today.