H. Srinivas

发表

The structural basis of Indisulam-mediated recruitment of RBM39 to the DCAF15-DDB1-DDA1 E3 ligase complex

V. Hornak, D. Bussiere, C. Wiesmann, 2019, bioRxiv.

Human Memory B Cells Harbor Diverse Cross‐Neutralizing Antibodies against BK and JC Polyomaviruses

John M. Lindner, M. Scharenberg, C. Wiesmann, 2019, Immunity.

Orally active 7-substituted (4-benzylphthalazin-1-yl)-2-methylpiperazin-1-yl]nicotinonitriles as active-site inhibitors of sphingosine 1-phosphate lyase for the treatment of multiple sclerosis.

C. Beerli, C. Bergsdorf, A. Billich, 2014, Journal of medicinal chemistry.

Feasibility and physiological relevance of designing highly potent aminopeptidase-sparing leukotriene A4 hydrolase inhibitors

R. Wolf, A. Hofmann, C. Bergsdorf, 2017, Scientific Reports.

Discovery and Characterization of Clinical Candidate LXE408 as a Kinetoplastid-Selective Proteasome Inhibitor for the Treatment of Leishmaniases

F. Supek, D. Caridha, Yen-Liang Chen, 2020, Journal of medicinal chemistry.

Mutations in sphingosine-1-phosphate lyase cause nephrosis with ichthyosis and adrenal insufficiency

K. Schwarz, T. Giese, R. Lifton, 2017, The Journal of clinical investigation.

Identification of a Novel Allosteric Inhibitory Site on Tryptophan Hydroxylase 1 Enabling Unprecedented Selectivity Over all Related Hydroxylases

Matthew Thomas, David Rowlands, Clemens Scheufler, 2017, Front. Pharmacol..

The Structure-Function Relationship of Stathmin and EB1- Two Key Proteins Regulating Microtubule Dynamics

H. Srinivas, 2005 .

Structural basis of indisulam-mediated RBM39 recruitment to DCAF15 E3 ligase complex

V. Hornak, D. Bussiere, C. Wiesmann, 2019, Nature Chemical Biology.

ADA2 is a lysosomal DNase regulating the type-I interferon response

R. Link, G. Kochs, G. Hartmann, 2020, bioRxiv.

A small-molecule inhibitor of C5 complement protein

M. Schirle, Mitsunori Kato, G. Michaud, 2019, Nature Chemical Biology.

Feasibility and physiological relevance of designing highly potent aminopeptidase-sparing leukotriene A4 hydrolase inhibitors

R. Wolf, A. Hofmann, C. Bergsdorf, 2017, Scientific Reports.

Interactions of Substrate with Calreticulin, an Endoplasmic Reticulum Chaperone* 210

A. Helenius, M. Kapoor, A. Surolia, 2003, The Journal of Biological Chemistry.

Discovery of LYS006, a Potent and Highly Selective Inhibitor of Leukotriene A4 Hydrolase.

K. Azzaoui, R. Wolf, P. Loetscher, 2021, Journal of medicinal chemistry.

Structure-Guided Elaboration of a Fragment-Like Hit into an Orally Efficacious Leukotriene A4 Hydrolase Inhibitor.

C. Beerli, Carlos A. Penno, H. Srinivas, 2024, Journal of medicinal chemistry.

Discovery of Amino Alcohols as Highly Potent, Selective, and Orally Efficacious Inhibitors of Leukotriene A4 Hydrolase.

G. Thoma, D. Bednarczyk, C. Beerli, 2023, Journal of medicinal chemistry.