J. Downing

发表

A multiplex RT-PCR assay for the detection of chimeric transcripts encoded by the risk-stratifying translocations of pediatric acute lymphoblastic leukemia

W. Williams, J. Kane, S. Shurtleff, 1998, Leukemia.

Genetic studies of childhood acute lymphoblastic leukemia with emphasis on p16, MLL, and ETV6 gene abnormalities: results of St Jude Total Therapy Study XII

F. Behm, M. Relling, C. Pui, 1997, Leukemia.

Increased risk for CNS relapse in pre-B cell leukemia with the t(1;19)/TCF3-PBX1

J. Downing, S. Raimondi, M. Relling, 2009, Leukemia.

IDH1 and IDH2 mutations in pediatric acute leukemia

S. Shurtleff, I. Radtke, C. Mullighan, 2011, Leukemia.

AML1/CBFβ transcription complex: its role in normal hematopoiesis and leukemia

J. Downing, 2001, Leukemia.

Significance of the TEL-AML1 fusion gene in childhood AML

C. Pui, J. Rubnitz, J. Downing, 1999, Leukemia.

The role of TEL fusion genes in pediatric leukemias

C. Pui, J. Rubnitz, J. Downing, 1999, Leukemia.

TEL/AML1 fusion resulting from a cryptic t(12;21) is the most common genetic lesion in pediatric ALL and defines a subgroup of patients with an excellent prognosis.

S. Shurtleff, F. Behm, S. Raimondi, 1995, Leukemia.

Characteristics and outcome of t(8;21)-positive childhood acute myeloid leukemia: a single institution's experience

J. Downing, F. Behm, S. Raimondi, 2002, Leukemia.

11q23 rearrangements in acute leukemia.

F. Behm, J. Rubnitz, J. Downing, 1996, Leukemia.

MN1 overexpression is an important step in the development of inv(16) AML

S. Shurtleff, E. Zwarthoff, G. Grosveld, 2007, Leukemia.

A Revised Definition for Cure of Childhood Acute Lymphoblastic Leukemia

J. Downing, S. Raimondi, M. Relling, 2014, Leukemia.

Long-term results of St. Jude Total Therapy studies 11, 12, 13A, 13B and 14 for childhood acute lymphoblastic leukemia

J. Downing, D. Campana, C. Pui, 2009, Leukemia.

Low frequency of TEL-AML1 in relapsed acute lymphoblastic leukemia supports a favorable prognosis for this genetic subgroup

J. Downing, F. Behm, M. Relling, 1999, Leukemia.

Genome-wide approach to identify risk factors for therapy-related myeloid leukemia

M. Relling, C. Pui, A. Bogni, 2006, Leukemia.

Identification of acquired copy number alterations and uniparental disomies in cytogenetically normal acute myeloid leukemia using high-resolution single-nucleotide polymorphism analysis

K Holzmann, I. Radtke, L. Bullinger, 2010, Leukemia.

TET1, a member of a novel protein family, is fused to MLL in acute myeloid leukemia containing the t(10;11)(q22;q23)

S. Mathew, S. Mukatira, S. Raimondi, 2003, Leukemia.

Multicolor spectral karyotyping identifies novel translocations in childhood acute lymphoblastic leukemia

J. Downing, S. Raimondi, P. Rao, 2001, Leukemia.

Comparison of genome sequencing and clinical genotyping for pharmacogenes

J. Downing, M. Relling, C. Mullighan, 2016, Clinical pharmacology and therapeutics.

Pediatric acute myeloid leukemia with NPM1 mutations is characterized by a gene expression profile with dysregulated HOX gene expression distinct from MLL-rearranged leukemias

J. Downing, S. Shurtleff, Xiaodong Zhou, 2007, Leukemia.

Coding polymorphisms in CD33 and response to gemtuzumab ozogamicin in pediatric patients with AML: a pilot study

S Pounds, D. Campana, C. Pui, 2009, Leukemia.

Rearrangement of the MLL gene confers a poor prognosis in childhood acute lymphoblastic leukemia, regardless of presenting age.

J. Downing, F. Behm, S. Raimondi, 1996, Blood.

TEL gene rearrangement in acute lymphoblastic leukemia: a new genetic marker with prognostic significance.

J. Downing, S. Shurtleff, F. Behm, 1997, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Rationale and design of Total Therapy Study XV for newly diagnosed childhood acute lymphoblastic leukemia.

D. Campana, W. Evans, M. Relling, 2004, Annals of hematology.