S. Inglott

发表

Genome-edited, donor-derived allogeneic anti-CD19 chimeric antigen receptor T cells in paediatric and adult B-cell acute lymphoblastic leukaemia: results of two phase 1 studies

Matthew J. Frigault, G. Lucchini, Jackie Chappell, 2020, The Lancet.

Identification of a c-MYB-directed therapeutic for acute myeloid leukemia

J. Bartram, S. Samarasinghe, J. de Boer, 2022, Leukemia.

PAX5 alterations in genetically unclassified childhood Precursor B‐cell acute lymphoblastic leukaemia

H. Kempski, A. Ford, P. Ancliff, 2015, British journal of haematology.

Abstract CT145: A Cancer Research UK phase I trial of anti-GD2 chimeric antigen receptor (CAR) transduced T-cells (1RG-CART) in patients with relapsed or refractory neuroblastoma

John Anderson, G. Barone, K. Straathof, 2018, Clinical Trials.

GATA2 mutations in sporadic and familial acute myeloid leukaemia patients with CEBPA mutations

J. Fitzgibbon, R. Hills, D. Linch, 2013, British journal of haematology.

Topoisomerase 2 b mutation impairs early B cell development

A. Fischer, K. Okkenhaug, C. Picard, 2020 .

Clinical benefit of a high‐throughput sequencing approach for minimal residual disease in acute lymphoblastic leukemia

J. Bartram, T. Brooks, S. Adams, 2019, Pediatric blood & cancer.

Antitumor activity without on-target off-tumor toxicity of GD2–chimeric antigen receptor T cells in patients with neuroblastoma

K. McHugh, I. Dragoni, A. Akarca, 2020, Science Translational Medicine.

Molecular remission of infant B-ALL after infusion of universal TALEN gene-edited CAR T cells

Adrian J. Thrasher, Waseem Qasim, Stuart Adams, 2017, Science Translational Medicine.

Enhanced CAR T cell expansion and prolonged persistence in pediatric patients with ALL treated with a low-affinity CD19 CAR

G. Lucchini, A. Hackshaw, P. Veys, 2019, Nature Medicine.

CD1a is rarely expressed in pediatric or adult relapsed/refractory T-ALL: implications for immunotherapy.

A. Khwaja, D. O’Connor, J. Bartram, 2020, Blood advances.

Discovery of a CD10 negative B-progenitor in human fetal life identifies unique ontogeny-related developmental programs.

B. Povinelli, P. Vyas, A. Mead, 2019, Blood.

Heterogeneous disease-propagating stem cells in juvenile myelomonocytic leukemia

Supat Thongjuea, B. Povinelli, R. Norfo, 2019, bioRxiv.

Single-cell transcriptomics reveals a distinct developmental state of KMT2A-rearranged infant B-cell acute lymphoblastic leukemia

Matthew D. Young, S. Teichmann, S. Behjati, 2022, Nature Medicine.

ARHGEF4 Regulates an Essential Oncogenic Program in t(12;21)-Associated Acute Lymphoblastic Leukemia

J. Bartram, S. Samarasinghe, A. Vora, 2020, HemaSphere.

H3K79me2/3 controls enhancer–promoter interactions and activation of the pan-cancer stem cell marker PROM1/CD133 in MLL-AF4 leukemia cells

P. Vyas, G. Buck, D. Knapp, 2020, Leukemia.

Single cell mRNA signals reveal a distinct developmental state of KMT2A-rearranged infant B-cell acute lymphoblastic leukemia

Matthew D. Young, S. Behjati, M. Haniffa, 2021, bioRxiv.

Chemotherapy induces canalization of cell state in childhood B-cell precursor acute lymphoblastic leukemia

I. Macaulay, N. Potter, P. Van Loo, 2021, Nature Cancer.

A human fetal liver-derived infant MLL-AF4 acute lymphoblastic leukemia model reveals a distinct fetal gene expression program

A. Mead, J. Bartram, T. Milne, 2021, Nature Communications.

A novel human fetal liver-derived model reveals that MLL-AF4 drives a distinct fetal gene expression program in infant ALL

A. Mead, J. Bartram, T. Milne, 2020, bioRxiv.

Blinatumomab for paediatric mixed phenotype acute leukaemia

J. Bartram, A. Vora, S. Adams, 2021, British journal of haematology.

A Novel Low Affinity CD19CAR Results in Durable Disease Remissions and Prolonged CAR T Cell Persistence without Severe CRS or Neurotoxicity in Patients with Paediatric ALL

G. Lucchini, A. Hackshaw, P. Veys, 2017 .

Engineering γδT cells limits tonic signaling associated with chimeric antigen receptors

D. Pe’er, Roshan Sharma, John Anderson, 2019, Science Signaling.

The Clinicogenomic Landscape of Induction Failure in Childhood and Young Adult T-Cell Acute Lymphoblastic Leukemia

P. Van Loo, J. Herrero, D. O’Connor, 2023, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Enhanced CAR T cell expansion and prolonged persistence in pediatric patients with ALL treated with a low-affinity CD19 CAR

G. Lucchini, A. Hackshaw, P. Veys, 2019, Nature Medicine.

Recalcitrant transient abnormal myelopoiesis in neonatal Down syndrome

J. Bartram, J. Chalker, S. Inglott, 2022, Pediatric blood & cancer.

High‐throughput sequencing of peripheral blood for minimal residual disease monitoring in childhood precursor B‐cell acute lymphoblastic leukemia: A prospective feasibility study

M. Hubank, J. Bartram, J. Hancock, 2021, Pediatric blood & cancer.

Flow cytometry of bone marrow aspirates from neuroblastoma patients is a highly sensitive technique for quantification of low-level neuroblastoma

S. Burchill, A. Serban, G. Barone, 2021, F1000Research.

Flow cytometry of bone marrow aspirates from neuroblastoma patients is a highly sensitive technique for quantification of low-level neuroblastoma.

S. Burchill, A. Serban, G. Barone, 2021, F1000Research.

Topoisomerase 2β mutation impairs early B cell development.

A. Fischer, K. Okkenhaug, S. Nejentsev, 2020, Blood.

High throughput sequencing in acute lymphoblastic leukemia reveals clonal architecture of central nervous system and bone marrow compartments

M. Hubank, J. Bartram, C. Halsey, 2017, Haematologica.

Therapy of Paediatric B-ALL with a Fast Off Rate CD19 CAR Leads to Enhanced Expansion and Prolonged CAR T Cell Persistence in Patients with Low Bone Marrow Tumour Burden, and Is Associated with a Favourable Toxicity Profile

G. Lucchini, A. Hackshaw, P. Veys, 2019, Blood.

PAX5 alterations in genetically unclassified childhood Precursor B‐cell acute lymphoblastic leukaemia

H. Kempski, A. Ford, P. Ancliff, 2015, British journal of haematology.