K. R. Ledesma

发表

Effect of multidrug resistance-conferring mutations on the fitness and virulence of Pseudomonas aeruginosa.

V. Tam, K. Poole, S. Kabbara, 2011, The Journal of antimicrobial chemotherapy.

Assessment of Minocycline and Polymyxin B Combination against Acinetobacter baumannii

V. Tam, Dongxu Sun, Jian Zhou, 2015, Antimicrobial Agents and Chemotherapy.

Simultaneous in vitro simulation of multiple antimicrobial agents with different elimination half-lives in a pre-clinical infection model

Brianna M. Eales, Paul R. Merlau, M. Nikolaou, 2020, bioRxiv.

Determining &bgr;-lactam exposure threshold to suppress resistance development in Gram-negative bacteria

A. Oliver, V. Tam, R. Cantón, 2017, The Journal of antimicrobial chemotherapy.

In vivo dynamics of carbapenem-resistant Pseudomonas aeruginosa selection after suboptimal dosing.

V. Tam, R. Ghose, A. Schilling, 2009, Diagnostic microbiology and infectious disease.

Temporal Interplay between Efflux Pumps and Target Mutations in Development of Antibiotic Resistance in Escherichia coli

V. Tam, Renu Singh, Michelle C. Swick, 2012, Antimicrobial Agents and Chemotherapy.

Novel Modeling Framework To Guide Design of Optimal Dosing Strategies for β-Lactamase Inhibitors

M. Nikolaou, V. Tam, Pratik Bhagunde, 2012, Antimicrobial Agents and Chemotherapy.

Clinical and genomic analysis of virulence-related genes in bloodstream infections caused by Acinetobacter baumannii

Brianna M. Eales, Paul R. Merlau, V. Tam, 2022, Virulence.

Quantitative Impact of Neutrophils on Bacterial Clearance in a Murine Pneumonia Model

M. Nikolaou, V. Tam, Kamilia Abdelraouf, 2011, Antimicrobial Agents and Chemotherapy.

Characterization of Amikacin Drug Exposure and Nephrotoxicity in an Animal Model

Katrina Chan, V. Tam, K. R. Ledesma, 2020, Antimicrobial Agents and Chemotherapy.

A robust LC-MS/MS method for amikacin: application to cellular uptake and pharmacokinetic studies.

Katrina Chan, V. Tam, Taijun Yin, 2020, Bioanalysis.

Modelling biphasic killing of fluoroquinolones: guiding optimal dosing regimen design.

M. Nikolaou, V. Tam, Renu Singh, 2011, The Journal of antimicrobial chemotherapy.

In Vitro Activity of MK-7655, a Novel β-Lactamase Inhibitor, in Combination with Imipenem against Carbapenem-Resistant Gram-Negative Bacteria

V. Tam, M. Motyl, Elizabeth B. Hirsch, 2012, Antimicrobial Agents and Chemotherapy.

Assessment of antimicrobial combinations for Klebsiella pneumoniae carbapenemase-producing K. pneumoniae.

V. Tam, Elizabeth B. Hirsch, Manisha Singh, 2013, The Journal of infectious diseases.

Pharmacokinetics and Pharmacodynamics of Minocycline against Acinetobacter baumannii in a Neutropenic Murine Pneumonia Model

V. Tam, Song Gao, Jian Zhou, 2017, Antimicrobial Agents and Chemotherapy.

Killing of Escherichia coli by beta-lactams at different inocula.

J. Quinn, V. Tam, K. R. Ledesma, 2009, Diagnostic microbiology and infectious disease.

Variability of polymyxin B major components in commercial formulations.

V. Tam, D. Chow, K. R. Ledesma, 2010, International journal of antimicrobial agents.

Characterization of Polymyxin B Biodistribution and Disposition in an Animal Model

L. Truong, V. Tam, J. Eriksen, 2015, Antimicrobial Agents and Chemotherapy.

Pharmacokinetics and efficacy of liposomal polymyxin B in a murine pneumonia model.

V. Tam, Kamilia Abdelraouf, D. Chow, 2013, International journal of antimicrobial agents.

Pharmacodynamics of moxifloxacin against a high inoculum of Escherichia coli in an in vitro infection model.

Renu Singh, Vincent H Tam, V. Tam, 2009, The Journal of antimicrobial chemotherapy.

Pharmacokinetics and Renal Disposition of Polymyxin B in an Animal Model

V. Tam, Kamilia Abdelraouf, K. R. Ledesma, 2012, Antimicrobial Agents and Chemotherapy.

In Vitro Potency of Various Polymyxin B Components

V. Tam, K. R. Ledesma, Henry Cao, 2011, Antimicrobial Agents and Chemotherapy.

An evaluation of multiple phenotypic screening methods for Klebsiella pneumoniae carbapenemase (KPC)-producing Enterobacteriaceae.

V. Tam, P. Zucchi, Elizabeth B. Hirsch, 2014, Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy.

Quantitative assessment of combination antimicrobial therapy against multidrug-resistant bacteria in a murine pneumonia model.

V. Tam, Renu Singh, R. Prince, 2010, The Journal of infectious diseases.

Pharmacodynamic Modeling of Aminoglycosides against Pseudomonas aeruginosa and Acinetobacter baumannii: Identifying Dosing Regimens To Suppress Resistance Development

Michael Nikolaou, Vincent H. Tam, Kimberly R. Ledesma, 2008, Antimicrobial Agents and Chemotherapy.

Predicting bacterial fitness cost associated with drug resistance.

M. Nikolaou, V. Tam, Kamilia Abdelraouf, 2012, The Journal of antimicrobial chemotherapy.

Transcriptional profiles of pulmonary innate immune responses to isogenic antibiotic‐susceptible and multidrug‐resistant Pseudomonas aeruginosa

V. Tam, K. R. Ledesma, R. Lewis, 2018, Microbiology and immunology.

Local Tissue Response to Subcutaneous Administration of Ceftriaxone in an Animal Model

Katrina Chan, V. Tam, K. Garey, 2019, Antimicrobial Agents and Chemotherapy.

Pharmacokinetics and Renal Disposition of Polymyxin B in an Animal Model

V. Tam, Kamilia Abdelraouf, K. R. Ledesma, 2012, Antimicrobial Agents and Chemotherapy.

Role of Renal Drug Exposure in Polymyxin B-Induced Nephrotoxicity

Pooja Manchandani, Vincent H. Tam, Kimberly R. Ledesma, 2017, Antimicrobial Agents and Chemotherapy.

Kidney Injury Associated with Telavancin Dosing Regimen in an Animal Model

L. Truong, V. Tam, Jian Zhou, 2015, Antimicrobial Agents and Chemotherapy.

Optimizing pharmacokinetics/pharmacodynamics of β-lactam/β-lactamase inhibitor combinations against high inocula of ESBL-producing bacteria.

Paul R. Merlau, M. Nikolaou, Katrina Chan, 2020, The Journal of antimicrobial chemotherapy.