Bret M. Benton

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Further Insights into the Mode of Action of the

C. S. Lunde, Yang Song, Bret M. Benton, 2012 .

Telavancin, a Multifunctional Lipoglycopeptide, Disrupts both Cell Wall Synthesis and Cell Membrane Integrity in Methicillin-Resistant Staphylococcus aureus

Deborah L. Higgins, K. Krause, J. Leung, 2005, Antimicrobial Agents and Chemotherapy.

Intrapulmonary Distribution of Intravenous Telavancin in Healthy Subjects and Effect of Pulmonary Surfactant on In Vitro Activities of Telavancin and Other Antibiotics

J. Shaw, M. Goldberg, K. Krause, 2007, Antimicrobial Agents and Chemotherapy.

Optimization of CoaD Inhibitors against Gram-Negative Organisms through Targeted Metabolomics.

Brian Y Feng, Lisha Wang, Mei Geng, 2017, ACS infectious diseases.

Fluorescence Microscopy Demonstrates Enhanced Targeting of Telavancin to the Division Septum of Staphylococcus aureus

Stephanie R Hartouni, C. S. Lunde, C. Rexer, 2010, Antimicrobial Agents and Chemotherapy.

Studies on the mechanism of telavancin decreased susceptibility in a laboratory-derived mutant.

B. Wilkinson, C. S. Lunde, Yang Song, 2013, Microbial drug resistance.

In vitro activity of telavancin against Gram-positive isolates from complicated skin and skin structure infections: results from 2 phase 3 (ATLAS) clinical studies.

K. Krause, S. Barriere, M. Kitt, 2010, Diagnostic microbiology and infectious disease.

Telavancin Disrupts the Functional Integrity of the Bacterial Membrane through Targeted Interaction with the Cell Wall Precursor Lipid II

M. Mammen, J. Janc, Stephanie R Hartouni, 2009, Antimicrobial Agents and Chemotherapy.

In vitro activity of telavancin against recent Gram-positive clinical isolates: results of the 2004-05 Prospective European Surveillance Initiative.

K. Krause, D. Sahm, C. Thornsberry, 2008, The Journal of antimicrobial chemotherapy.

In Vitro Activity of Telavancin against Resistant Gram-Positive Bacteria

K. Krause, D. Debabov, Terry Wu, 2008, Antimicrobial Agents and Chemotherapy.

Comparative Surveillance Study of Telavancin Activity against Recently Collected Gram-Positive Clinical Isolates from across the United States

K. Krause, D. Sahm, C. Thornsberry, 2008, Antimicrobial Agents and Chemotherapy.

Topoisomerase Inhibitors Addressing Fluoroquinolone Resistance in Gram-Negative Bacteria.

Sarah L. Williams, D. Bussiere, Sylvia Ma, 2020, Journal of medicinal chemistry.

In vitro activity of telavancin and occurrence of vancomycin heteroresistance in isolates from patients enrolled in phase 3 clinical trials of hospital-acquired pneumonia.

K. Krause, S. Barriere, C. S. Lunde, 2012, Diagnostic microbiology and infectious disease.

Further Insights into the Mode of Action of the Lipoglycopeptide Telavancin through Global Gene Expression Studies

B. Wilkinson, C. S. Lunde, Yang Song, 2012, Antimicrobial Agents and Chemotherapy.

Two Distinct Mechanisms of Inhibition of LpxA Acyltransferase Essential for Lipopolysaccharide Biosynthesis.

S. Subramanian, E. Ornelas, Sylvia Ma, 2020, Journal of the American Chemical Society.

Two distinct mechanisms of small molecule inhibition of LpxA acyltransferase essential for lipopolysaccharide biosynthesis

C. Ho, M. Li, S. Subramanian, 2019, bioRxiv.

Synthesis of ciprofloxacin dimers for evaluation of bacterial permeability in atypical chemical space.

D. Chin, J. Leeds, M. LaMarche, 2015, Bioorganic & medicinal chemistry letters.

Application of Virtual Screening to the Identification of New LpxC Inhibitor Chemotypes, Oxazolidinone and Isoxazoline.

W. Shu, C. Bellamacina, G. Tonn, 2018, Journal of medicinal chemistry.

Activity of telavancin against heterogeneous vancomycin-intermediate Staphylococcus aureus (hVISA) in vitro and in an in vivo mouse model of bacteraemia.

K. Krause, S. Hegde, J. Blais, 2010, The Journal of antimicrobial chemotherapy.

In vitro activity of telavancin and comparator antimicrobial agents against a panel of genetically defined staphylococci.

D. Farrell, K. Krause, Bret M. Benton, 2011, Diagnostic microbiology and infectious disease.

Efficacy of telavancin in a murine model of bacteraemia induced by methicillin-resistant Staphylococcus aureus.

K. Krause, S. Hegde, Bret M. Benton, 2006, The Journal of antimicrobial chemotherapy.

Specificity of Induction of the vanA and vanB Operons in Vancomycin-Resistant Enterococci by Telavancin

M. Mammen, J. Janc, K. Krause, 2010, Antimicrobial Agents and Chemotherapy.

O258 Telavancin inhibits peptidoglycan biosynthesis through preferential targeting of transglycosylation: evidence for a multivalent interaction between telavancin and lipid II

M. Mammen, J. Janc, E. Breukink, 2007 .

Antistaphylococcal Activity of TD-1792, a Multivalent Glycopeptide-Cephalosporin Antibiotic

K. Krause, J. Blais, Bret M. Benton, 2011, Antimicrobial Agents and Chemotherapy.

In Vitro Activity of Telavancin against Resistant Gram-Positive Bacteria

K. Krause, D. Debabov, Bret M. Benton, 2008, Antimicrobial Agents and Chemotherapy.