Kristen John

发表

A Cell-Free Fluorometric High-Throughput Screen for Inhibitors of Rtt109-Catalyzed Histone Acetylation

Jayme L. Dahlin, Junhong Han, Zhiguo Zhang, 2013, PloS one.

Development of WEE2 kinase inhibitors as novel non-hormonal female contraceptives that target meiosis†

E. Schönbrunn, G. Georg, J. Hawkinson, 2020, Biology of Reproduction.

Post-HTS case report and structural alert: Promiscuous 4-aroyl-1,5-disubstituted-3-hydroxy-2H-pyrrol-2-one actives verified by ALARM NMR.

Jayme L. Dahlin, Michael A. Walters, J. Willem M. Nissink, 2015, Bioorganic & medicinal chemistry letters.

The anti-parasitic agent suramin and several of its analogues are inhibitors of the DNA binding protein Mcm10

W. Chazin, B. Eichman, G. Georg, 2019, Open Biology.

High-Throughput Screening for Growth Inhibitors Using a Yeast Model of Familial Paraganglioma

J. Bida, E. Poeschla, G. Georg, 2013, PloS one.

Development of allosteric, selective cyclin-dependent kinase 2 (CDK2) inhibitors that are negatively cooperative with cyclin binding and show potential as contraceptive agents

N. Levinson, E. Schönbrunn, V. Chennathukuzhi, 2022, bioRxiv.

7-Methylation of Chenodeoxycholic Acid Derivatives Yields a Substantial Increase in TGR5 Receptor Potency.

Elizabeth A Ambrose, A. Khoruts, A. Nakhi, 2019, Journal of medicinal chemistry.

Quantifying the Selectivity of Protein-Protein and Small Molecule Interactions with Fluorinated Tandem Bromodomain Reader Proteins.

A. Pandey, J. Hawkinson, J. Solberg, 2020, ACS chemical biology.

Screening through Lead Optimization of High Affinity, Allosteric Cyclin-Dependent Kinase 2 (CDK2) Inhibitors as Male Contraceptives That Reduce Sperm Counts in Mice.

Nan Wang, N. Levinson, E. Schönbrunn, 2023, Journal of medicinal chemistry.

Discovery of a Pan-Melanocortin Receptor Antagonist [Ac-DPhe(pI)-Arg-Nal(2')-Orn-NH2] at the MC1R, MC3R, MC4R, and MC5R that Mediates an Increased Feeding Response in Mice and a 40-Fold Selective MC1R Antagonist [Ac-DPhe(pI)-DArg-Nal(2')-Arg-NH2].

Mark D. Ericson, M. M. Lunzer, K. Freeman, 2023, Journal of medicinal chemistry.

Post-HTS case report and structural alert: Promiscuous 4-aroyl-1,5-disubstituted-3-hydroxy-2H-pyrrol-2-one actives verified by ALARM NMR.

Jayme L. Dahlin, Zhiguo Zhang, M. Walters, 2015, Bioorganic & Medicinal Chemistry Letters.

Development of allosteric and selective CDK2 inhibitors for contraception with negative cooperativity to cyclin binding

N. Levinson, E. Schönbrunn, J. Hawkinson, 2023, Nature communications.