M. Rab

发表

Rapid and reproducible characterization of sickling during automated deoxygenation in sickle cell disease patients

G. Pasterkamp, M. Bartels, M. Safo, 2019, American journal of hematology.

Persistent changes in circulating white blood cell populations after splenectomy

G. Rijkers, O. de Weerdt, H. van Velzen-Blad, 2018, International Journal of Hematology.

Metabolic Fingerprint in Hereditary Spherocytosis Correlates With Red Blood Cell Characteristics and Clinical Severity

E. Nieuwenhuis, M. Bartels, J. Jans, 2021, HemaSphere.

Effects of Genotypes and Treatment on Oxygenscan Parameters in Sickle Cell Disease

Celeste K. Kanne, Y. Bertrand, V. Sheehan, 2021, Cells.

Impaired Cytoskeletal and Membrane Biophysical Properties of Acanthocytes in Hypobetalipoproteinemia – A Case Study

D. Alsteens, P. van der Smissen, Y. Larondelle, 2021, Frontiers in Physiology.

Rapid diagnosis of hereditary haemolytic anaemias using automated rheoscopy and supervised machine learning

G. Streekstra, J. Dobbe, A. Toye, 2020, British journal of haematology.

Blood rheology biomarkers in sickle cell disease

S. Shevkoplyas, V. Sheehan, M. Rab, 2020, Experimental biology and medicine.

Density, heterogeneity and deformability of red cells as markers of clinical severity in hereditary spherocytosis

R. Schiffelers, L. P. Verhagen, L. Kaestner, 2019, Haematologica.

AG-348 (mitapivat), an allosteric activator of red blood cell pyruvate kinase, increases enzymatic activity, protein stability, and adenosine triphosphate levels over a broad range of PKLR genotypes

C. Kung, J. Hixon, L. Dang, 2020, Haematologica.

Characterization of Sickling During Controlled Automated Deoxygenation with Oxygen Gradient Ektacytometry.

V. Sheehan, R. van Wijk, B. V. van Oirschot, 2019, Journal of visualized experiments : JoVE.

Safety and efficacy of mitapivat, an oral pyruvate kinase activator, in sickle cell disease: A phase 2, open‐label study

M. Bartels, B. Biemond, J. Jans, 2022, American journal of hematology.

Comparisons of oxygen gradient ektacytometry parameters between sickle cell patients with or without α‐thalassaemia

V. Sheehan, Y. Bertrand, P. Joly, 2021, British journal of haematology.

Mechanical Stress Induces Ca2+-Dependent Signal Transduction in Erythroblasts and Modulates Erythropoiesis

M. von Lindern, L. Kaestner, R. van Wijk, 2021, International journal of molecular sciences.

Ektacytometry Analysis of Post-splenectomy Red Blood Cell Properties Identifies Cell Membrane Stability Test as a Novel Biomarker of Membrane Health in Hereditary Spherocytosis

M. Bartels, W. V. van Solinge, R. van Wijk, 2021, Frontiers in Physiology.

Decreased activity and stability of pyruvate kinase in sickle cell disease: a novel target for therapy by mitapivat.

C. Kung, L. Dang, V. Chubukov, 2021, Blood.

Red blood cells from patients with sitosterolemia exhibit impaired membrane lipid composition and distribution and decreased deformability

A. Koster, P. van der Smissen, Y. Larondelle, 2023, Frontiers in Hematology.

Antibody response to pneumococcal polysaccharide vaccination in patients treated with biologicals

G. Rijkers, M. Rab, 2012 .

Pharmacodynamic Effects of AG-946, a Highly Potent Next-Generation Activator of Pyruvate Kinase, in Ex Vivo Treatment of Red Blood Cells from Sickle Cell Disease Patients

C. Kung, L. Dang, J. Jans, 2021, Blood.

Safety and Efficacy of Mitapivat (AG-348), an Oral Activator of Pyruvate Kinase R, in Subjects with Sickle Cell Disease: A Phase 2, Open-Label Study (ESTIMATE)

M. Bartels, J. Jans, W. V. van Solinge, 2021, Blood.

PIEZO1 gain-of-function mutations delay reticulocyte maturation in hereditary xerocytosis

G. Streekstra, J. Dobbe, A. Toye, 2019, Haematologica.

Oxygen gradient ektacytometry‐derived biomarkers are associated with vaso‐occlusive crises and correlate with treatment response in sickle cell disease

V. Sheehan, M. Bartels, P. Joly, 2020, American journal of hematology/oncology.

Comment on: Oxygen gradient ektacytometry does not predict pain in children with sickle cell anaemia

V. Sheehan, P. Connes, R. van Wijk, 2022, British journal of haematology.

Rheological Assessments of Sickle Cell Patients Post Allogeneic Hematopoietic Cell Transplant

S. Shevkoplyas, V. Sheehan, R. Wijk, 2019, Blood.

Methodological aspects of oxygen gradient ektacytometry in sickle cell disease: Effects of sample storage on outcome parameters in distinct patient subgroups.

V. Sheehan, P. Joly, P. Connes, 2020, Clinical hemorheology and microcirculation.

A functional spleen contributes to afucosylated IgG in humans

G. Vidarsson, C. E. van der Schoot, J. Zwaginga, 2021, Scientific Reports.

Activation of pyruvate kinase as therapeutic option for rare hemolytic anemias: Shedding new light on an old enzyme.

M. Bartels, R. van Wijk, K. Kuo, 2023, Blood reviews.

Comprehensive in silico and functional studies for classification of EPAS1/HIF2A genetic variants identified in patients with erythrocytosis

F. Girodon, H. Cario, A. Gimenez-Roqueplo, 2022, Haematologica.

A novel missense variant in ATP11C is associated with reduced red blood cell phosphatidylserine flippase activity and mild hereditary hemolytic anemia

Steffen M. Recktenwald, R. Molday, L. Kaestner, 2023, American journal of hematology.

Methodological aspects of the oxygenscan in sickle cell disease: A need for standardization

V. Sheehan, P. Joly, P. Connes, 2019, American journal of hematology.

Characterization of genetic variants in the EGLN1/PHD2 gene identified in a European collection of patients with erythrocytosis

T. Haferlach, N. Casadevall, F. Girodon, 2023, Haematologica.

Effect of Cell Age and Membrane Rigidity on Red Blood Cell Shape in Capillary Flow

Steffen M. Recktenwald, L. Kaestner, A. Darras, 2023, Cells.