D. Savery

发表

Rho-kinase-dependent actin turnover and actomyosin disassembly are necessary for mouse spinal neural tube closure

N. Greene, A. Copp, W. Witke, 2015, Journal of Cell Science.

Regulation of cell protrusions by small GTPases during fusion of the neural folds

N. Greene, A. Copp, Peter M. G. Munro, 2016, eLife.

Regulation of glycine metabolism by the glycine cleavage system and conjugation pathway in mouse models of non‐ketotic hyperglycinemia

N. Greene, A. Copp, S. Heales, 2020, Journal of inherited metabolic disease.

Spina bifida-predisposing heterozygous mutations in Planar Cell Polarity genes and Zic2 reduce bone mass in young mice

N. Greene, A. Copp, P. Stanier, 2018, Scientific Reports.

Glycine decarboxylase deficiency causes neural tube defects and features of non-ketotic hyperglycinemia in mice

M. Brosnan, J. Brosnan, N. Greene, 2015, Nature Communications.

Partitioning of One-Carbon Units in Folate and Methionine Metabolism Is Essential for Neural Tube Closure

N. Greene, A. Copp, M. Ralser, 2017, Cell reports.

A Gluten-Free Diet as an Intervention for Autism and Associated Spectrum Disorders: Preliminary Findings

P. Whiteley, P. Shattock, J. Rodgers, 1999 .

Refinement of inducible gene deletion in embryos of pregnant mice

N. Greene, A. Copp, G. Galea, 2019, Birth defects research.

Cellular mechanisms underlying Pax3-related neural tube defects and their prevention by folic acid

N. Greene, A. Copp, A. Palmer, 2019, Disease Models & Mechanisms.

The non-canonical Wnt-PCP pathway shapes the mouse caudal neural plate

L. Davidson, Deepthi S. Vijayraghavan, J. Sánchez-Alcázar, 2018, Development.

Vangl2–environment interaction causes severe neural tube defects, without abnormal neuroepithelial convergent extension

N. Greene, A. Copp, P. Stanier, 2021, Disease models & mechanisms.

Neural tube closure depends on expression of Grainyhead-like 3 in multiple tissues

N. Greene, B. Andersen, A. Copp, 2018, Developmental biology.

Over-expression of Grhl2 causes spina bifida in the Axial defects mutant mouse

N. Greene, A. Copp, W. Lamers, 2011, Human molecular genetics.

Genetic approaches in mice demonstrate that neuro-mesodermal progenitors express T/Brachyury but not Sox2

J. Martinez-Barbera, N. Greene, A. Copp, 2018 .

Impaired folate 1-carbon metabolism causes formate-preventable hydrocephalus in glycine decarboxylase–deficient mice

N. Greene, A. Copp, S. Waddington, 2019, The Journal of clinical investigation.

Overexpression of Grainyhead-like 3 causes spina bifida and interacts genetically with mutant alleles of Grhl2 and Vangl2 in mice

N. Greene, B. Andersen, A. Copp, 2018, Human molecular genetics.

Vangl2 disruption alters the biomechanics of late spinal neurulation leading to spina bifida in mouse embryos

N. Greene, A. Copp, D. Henderson, 2018, Disease Models & Mechanisms.

Mouse whole embryo culture: Evaluating the requirement for rat serum as culture medium

N. Greene, A. Copp, Lucy H Culshaw, 2019, Birth defects research.

Dynamic acetylation profile during mammalian neurulation

N. Greene, A. Copp, V. Massa, 2019, Birth defects research.

Vangl-dependent planar cell polarity signalling is not required for neural crest migration in mammals

N. Greene, A. Copp, V. Massa, 2014, Development.

Evidence of functional redundancy between MID proteins: implications for the presentation of Opitz syndrome.

J. Hazan, A. Lumsden, A. Granata, 2005, Developmental biology.

Severe neural tube defects due to failure of closure initiation can arise without abnormality of neuroepithelial convergent extension

N. Greene, A. Copp, P. Stanier, 2021, bioRxiv.

Chronic D-fenfluramine decreases serotonin transporter messenger RNA expression in dorsal raphe nucleus.

J. Priestley, M. Rattray, C. Bendotti, 1994, European journal of pharmacology.

Novel exomphalos genetic mouse model: The importance of accurate phenotypic classification

M. Lythgoe, S. Eaton, P. Scambler, 2013, Journal of pediatric surgery.

Two populations of cells that express preprocholecystokinin mRNA in ventral periaqueductal grey

J. Priestley, M. Rattray, D. Savery, 1992, Neuroscience Letters.

Genetic interaction of Pax3 mutation and canonical Wnt signaling modulates neural tube defects and neural crest abnormalities

N. Greene, A. Copp, A. Palmer, 2021, Genesis.

Biomechanical coupling facilitates spinal neural tube closure in mouse embryos

Ana Rolo, Gauden Galea, Dawn Savery, 2017, Proceedings of the National Academy of Sciences.

Novel mouse model of encephalocele: post-neurulation origin and relationship to open neural tube defects

N. Greene, A. Copp, A. Rolo, 2019, Disease Models & Mechanisms.

Convergent extension analysis in mouse whole embryo culture.

N. Greene, A. Copp, V. Massa, 2012, Methods in molecular biology.

Apoptosis is not required for mammalian neural tube closure

N. Greene, A. Copp, R. Flavell, 2009, Proceedings of the National Academy of Sciences.

Gene-environment interactions in the causation of neural tube defects: folate deficiency increases susceptibility conferred by loss of Pax3 function.

Katie A. Burren, N. Greene, H. Blom, 2008, Human molecular genetics.

Gene – environment interactions in the causation of neural tube defects : folate deficiency increases susceptibility conferred by loss of Pax 3 function

Katie A. Burren, N. Greene, H. Blom, 2008 .

Convergent extension, planar-cell-polarity signalling and initiation of mouse neural tube closure

N. Greene, A. Copp, D. Gerrelli, 2007, Development.

Urinary compounds in autism.

T. Berney, P. Shattock, K. Bretherton, 2004, Journal of intellectual disability research : JIDR.

Rapid analysis of low levels of indolyl-3-acryloylglycine in human urine by high-performance liquid chromatography.

P. Shattock, D. Savery, M. Mills, 1998, Journal of chromatography. B, Biomedical sciences and applications.

Neural tube defects induced by folate deficiency in mutant curly tail (Grhl3) embryos are associated with alteration in folate one-carbon metabolism but are unlikely to result from diminished methylation.

Katie A. Burren, N. Greene, R. Rozen, 2010, Birth defects research. Part A, Clinical and molecular teratology.

Mechanical loading of cranial joints minimizes the craniofacial phenotype in Crouzon syndrome

Dominic Jones, A. Alazmani, M. Moazen, 2022, Scientific Reports.

The mechanobiology of craniosynostosis in Crouzon syndrome

Dominic Jones, A. Alazmani, M. Moazen, 2021 .

Integrin-Mediated Focal Anchorage Drives Epithelial Zippering during Mouse Neural Tube Closure

N. Greene, A. Copp, R. Fässler, 2020, Developmental cell.

A combined in situ hybridization and immunofluorescence procedure allowing visualisation of peptide mRNA and serotonin in single sections

J. Priestley, M. Rattray, S. Averill, 1993, Journal of Neuroscience Methods.

Planar Cell Polarity Aligns Osteoblast Division in Response to Substrate Strain

Gary S Stein, Dawn Savery, L. Lanyon, 2015, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Cellular basis of neuroepithelial bending during mouse spinal neural tube closure

N. Greene, A. Copp, P. Tam, 2015, Developmental biology.

Distribution of messenger RNAs encoding enkephalin, substance P, somatostatin, galanin, vasoactive intestinal polypeptide, neuropeptide Y, and calcitonin gene‐related peptide in the midbrain periaqueductal grey in the rat

J. Priestley, M. Rattray, C. Marden, 1994, The Journal of comparative neurology.

Spina bifida-predisposing heterozygous mutations in Planar Cell Polarity genes and Zic2 reduce bone mass in young mice

N. Greene, A. Copp, P. Stanier, 2018, Scientific Reports.

Use of high‐frequency ultrasound to study the prenatal development of cranial neural tube defects and hydrocephalus in Gldc‐deficient mice

Anna L David, Mark F Lythgoe, Dawn Savery, 2017, Prenatal diagnosis.

Repeated administration of MDMA down-regulates preprocholecystokinin mRNA expression but not tyrosine hydroxylase mRNA expression in neurones of the rat substantia nigra.

J. Priestley, M. Rattray, D. Savery, 1994, Brain research. Molecular brain research.

In Amnio MRI of Mouse Embryos

M. Lythgoe, S. Eaton, P. Scambler, 2014, PloS one.

Nucleotide precursors prevent folic acid-resistant neural tube defects in the mouse

N. Greene, A. Copp, K. Leung, 2013, Brain : a journal of neurology.

Identification of indolyl‐3‐acryloylglycine in the urine of people with autism

Rosaleen J. Anderson, W. J. Lough, P. Groundwater, 2002, The Journal of pharmacy and pharmacology.

Dual mechanism underlying failure of neural tube closure in the Zic2 mutant mouse.

N. Greene, A. Copp, G. Galea, 2023, Disease models & mechanisms.